Showing Protein Coagulation factor VII (BMDBP01306)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01306 |
| Secondary Accession Numbers |
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| Name | Coagulation factor VII |
| Synonyms | Not Available |
| Gene Name | F7 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 12 |
| Locus | Not Available |
| SNPs | F7 |
| Gene Sequence |
>1344 bp ATGCTGTCCCAGGCCTGGGCTCTGGCCCTCCTCTGCTTTCTGCTCAGCCTGTGGGGGTCC CTGCCGGCAGTCTTCCTGCCCCAGGAGCAGGCCCTCAGCATCCTGCATCGGCCTCGGCGT GCCAACGGGTTCCTGGAGGAGCTGCTGCCGGGCTCGCTGGAGCGGGAGTGCAGGGAGGAG CTCTGCTCCTTCGAGGAAGCCCACGAGATCTTCCGCAACGAGGAGAGGACGAGGCAGTTC TGGGTTTCCTACAATGACGGGGACCAGTGCGCCTCCAGCCCCTGCCAGAACGGGGGCTCC TGTGAGGACCAGCTCCGGTCCTACATCTGCTTCTGCCCCGACGGCTTCGAGGGCCGGAAC TGTGAGACCGACAAGCAGAGCCAGCTGATCTGCGCCAACGACAATGGCGGCTGTGAGCAG TACTGTGGGGCTGACCCGGGGGCCGGGCGCTTCTGCTGGTGCCATGAGGGCTACGCGCTC CAGGCAGACGGGGTGTCCTGCGCACCCACAGTGGAATATCCGTGCGGGAAAATACCTGTT CTGGAAAAAAGAAATGGCAGCAAGCCCCAAGGGCGAATTGTGGGGGGCCACGTCTGCCCC AAAGGGGAATGCCCCTGGCAGGCCATGCTGAAGCTGAACGGGGCGCTGCTGTGCGGGGGC ACCCTGGTCGGCCCGGCCTGGGTGGTCTCCGCCGCCCACTGCTTCGAAAGGCTCCGGAGC AGGGGGAACCTGACGGCTGTGCTGGGCGAGCACGACCTCAGCCGCGTGGAGGGCCCAGAG CAGGAGCGGCGGGTGGCGCAGATCATTGTCCCCAAGCAGTACGTGCCGGGCCAGACGGAC CACGACGTGGCCCTGCTGCAGCTGGCCCAGCCCGTGGCCCTGGGCGACCACGTGGCACCC CTCTGTCTGCCCGACCCGGACTTCGCGGACCAGACGCTGGCCTTCGTGCGCTTCTCGGCC GTCAGCGGCTGGGGCCAGCTCCTGGAGCGCGGGGTCACCGCCCGCAAGCTCATGGTGGTG CTGGTGCCCCGGCTGCTAACCCAGGACTGCCTGCAGCAGTCGCGCCAGAGGCCCGGCGGG CCTGTGGTCACGGACAACATGTTCTGCGCTGGCTATAGCGACGGCAGCAAGGATGCCTGC AAGGGGGACAGTGGGGGCCCGCACGCCACACGCTTCCGGGGCACCTGGTTCCTGACCGGC GTCGTCAGCTGGGGCGAGGGCTGCGCGGCAGCCGGCCACTTTGGGATCTACACGCGGGTC TCCCGCTACACGGCCTGGCTGCGGCAGCTGATGGGCCACCCGCCGTCCAGGCAGGGCTTC TTCCAGGTCCCGCTGCTGCCCTAG |
| Protein Properties | |
| Number of Residues | 447 |
| Molecular Weight | 48961.0 |
| Theoretical pI | 6.42 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions | Not Available |
| Protein Sequence |
>Coagulation factor VII MLSQAWALALLCFLLSLWGSLPAVFLPQEQALSILHRPRRANGFLEELLPGSLERECREE LCSFEEAHEIFRNEERTRQFWVSYNDGDQCASSPCQNGGSCEDQLRSYICFCPDGFEGRN CETDKQSQLICANDNGGCEQYCGADPGAGRFCWCHEGYALQADGVSCAPTVEYPCGKIPV LEKRNGSKPQGRIVGGHVCPKGECPWQAMLKLNGALLCGGTLVGPAWVVSAAHCFERLRS RGNLTAVLGEHDLSRVEGPEQERRVAQIIVPKQYVPGQTDHDVALLQLAQPVALGDHVAP LCLPDPDFADQTLAFVRFSAVSGWGQLLERGVTARKLMVVLVPRLLTQDCLQQSRQRPGG PVVTDNMFCAGYSDGSKDACKGDSGGPHATRFRGTWFLTGVVSWGEGCAAAGHFGIYTRV SRYTAWLRQLMGHPPSRQGFFQVPLLP |
| External Links | |
| GenBank ID Protein | AAX46431.1 |
| UniProtKB/Swiss-Prot ID | P22457 |
| UniProtKB/Swiss-Prot Entry Name | FA7_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BT021584 |
| GeneCard ID | F7 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |