Showing Protein Calpain-1 catalytic subunit (BMDBP01316)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01316 |
| Secondary Accession Numbers | None |
| Name | Calpain-1 catalytic subunit |
| Synonyms | Not Available |
| Gene Name | CAPN1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 29 |
| Locus | Not Available |
| SNPs | CAPN1 |
| Gene Sequence |
>2151 bp ATGGCCGAGGAGTTCATCACTCCGGTGTACTGCACCGGGGTGTCTGCACAAGTGCAGAAG CAGCGGGCCAAGGAGCTGGGCCTGGGCCGCCATGAAAATGCCATCAAGTACCTGGGCCAG GATTACGAGCAGCTGCGGGTTCACTGCCTGCAAAGAGGGGCCCTTTTCCGTGACGAGGCT TTCCCCCCAGTGCCCCAGAGCCTGGGCTTCAAGGAGCTGGGCCCCAACTCCTCCAAAACC TATGGCATCAAGTGGAAGCGTCCCACGGAGCTGTTCTCAAACCCCCAGTTCATCGTGGAT GGAGCCACCCGCACGGACATCTGCCAGGGCGCACTGGGGGACTGTTGGCTCCTGGCTGCC ATCGCCTCCCTTACCCTCAATGACACCCTCCTGCACCGAGTAGTTCCACATGGCCAAAGC TTCCAGGATGGCTACGCTGGCATCTTCCATTTCCAGCTGTGGCAGTTTGGTGAGTGGGTG GATGTGGTGGTGGATGACCTGCTGCCCACCAAGGACGGGAAGCTGGTGTTTGTGCACTCT GCCCAAGGCAACGAGTTCTGGAGCGCCCTGCTGGAGAAAGCCTATGCCAAGGTGAACGGC AGCTACGAGGCCCTCTCAGGAGGCAGCACATCTGAGGGCTTTGAGGACTTCACCGGCGGA GTCACCGAGTGGTACGAGCTGCGCAAGGCGCCCAGCGACCTCTACAACATCATCCTCAAG GCCCTGGAGCGTGGCTCCCTGCTGGGCTGCTCCATCGATATCTCCAGCATTCTGGACATG GAGGCTGTCACCTTCAAGAAGCTGGTGAAGGGCCACGCCTACTCTGTGACCGGGGCCAAA CAGGTGAACTACCAGGGCCAGATGGTGAACCTGATCCGGATGCGGAACCCCTGGGGCGAG GTGGAGTGGACAGGAGCCTGGAGTGACGGCTCCTCGGAGTGGAACGGCGTGGACCCTTAC ATGCGGGAGCAGCTCCGGGTCAAGATGGAGGATGGGGAGTTCTGGATGTCATTCCGAGAC TTCATGCGTGAATTCACCCGCCTGGAGATCTGCAACCTGACACCCGACGCGCTCAAGAGC CAGAGGTTCCGCAACTGGAACACCACCCTGTATGAGGGCACCTGGCGGCGGGGGAGCACC GCGGGGGGCTGCCGCAACTACCCAGCCACTTTCTGGGTGAACCCCCAGTTCAAGATCCGG CTGGAGGAGACGGATGACCCGGACCCCGACGACTACGGGGGTCGCGAGTCAGGCTGCAGC TTCCTGCTCGCCCTCATGCAGAAGCACCGCCGTCGGGAGCGCCGTTTCGGCCGTGACATG GAGACCATAGGCTTCGCTGTCTACGAGGTCCCTCCGGAGCTGATGGGCCAGCCGGCCGTG CATCTGAAGCGGGACTTCTTCCTGTCCAACGCCTCCCGGGCCCGGTCCGAGCAGTTCATC AACCTGCGGGAGGTCAGCACCCGCTTCCGCCTGCCGCCTGGGGAGTACGTGGTGGTGCCC TCCACCTTCGAGCCCAACAAGGAAGGTGACTTTGTGCTGCGTTTCTTCTCAGAGAAGAGC GCAGGGACCCAAGAGCTGGATGACCAGGTCCAGGCCAATCTCCCCGACGAGCAAGTGCTC TCAGAAGAGGAGATTGATGAGAACTTCAAGTCCCTCTTCAGACAACTGGCAGGGGAGGAC ATGGAGATCAGCGTCAAGGAGCTGCGGACCATCCTCAACAGGATCATCAGCAAACACAAA GACCTGCGGACCACGGGCTTCAGCCTGGAGTCCTGCCGCAGCATGGTCAACCTCATGGAT CGCGACGGCAATGGCAAACTGGGCCTGGTGGAGTTCAACATCCTATGGAACCGGATCCGG AATTACCTGTCCATCTTCCGGAAGTTTGACCTGGACAAGTCGGGCAGCATGAGTGCCTAT GAAATGCGGATGGCCATTGAGTTTGCAGGCTTCAAGCTCAACAAGAAGCTGTACGAGCTC ATTATCACCCGCTACTCGGAGCCCGACCTGGCCGTGGACTTCGACAACTTCGTGTGCTGC CTGGTGCGGCTGGAGACCATGTTCCGGTTTTTCAAAACTCTGGACACTGATCTGGATGGA GTGGTGACCTTTGACTTGTTTAAGTGGTTACAGCTGACCATGTTTGCGTGA |
| Protein Properties | |
| Number of Residues | 716 |
| Molecular Weight | 82207.0 |
| Theoretical pI | 5.26 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Calpain-1 catalytic subunit MAEEFITPVYCTGVSAQVQKQRAKELGLGRHENAIKYLGQDYEQLRVHCLQRGALFRDEA FPPVPQSLGFKELGPNSSKTYGIKWKRPTELFSNPQFIVDGATRTDICQGALGDCWLLAA IASLTLNDTLLHRVVPHGQSFQDGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHS AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYNIILK ALERGSLLGCSIDISSILDMEAVTFKKLVKGHAYSVTGAKQVNYQGQMVNLIRMRNPWGE VEWTGAWSDGSSEWNGVDPYMREQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS QRFRNWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDPDPDDYGGRESGCS FLLALMQKHRRRERRFGRDMETIGFAVYEVPPELMGQPAVHLKRDFFLSNASRARSEQFI NLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTQELDDQVQANLPDEQVL SEEEIDENFKSLFRQLAGEDMEISVKELRTILNRIISKHKDLRTTGFSLESCRSMVNLMD RDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIEFAGFKLNKKLYEL IITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA |
| External Links | |
| GenBank ID Protein | AAF64504.2 |
| UniProtKB/Swiss-Prot ID | Q27970 |
| UniProtKB/Swiss-Prot Entry Name | CAN1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF248054 |
| GeneCard ID | CAPN1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |