Showing Protein Protein phosphatase 1 regulatory subunit 3B (BMDBP01321)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01321 |
| Secondary Accession Numbers | None |
| Name | Protein phosphatase 1 regulatory subunit 3B |
| Synonyms | Not Available |
| Gene Name | PPP1R3B |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Not Available |
| Specific Function | Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 27 |
| Locus | Not Available |
| SNPs | PPP1R3B |
| Gene Sequence |
>855 bp ATGGCCGTGGACATCGAGTGCCGGTACAGCTGCATGGCCCCCTCCTTGCGCAGAGAGCGG TTTGCCTTCCAGATTGCCCCAAAGCCAAGCAAACCTCTGAGGCCTTGTATTCAGCTGAGC GGCAAGAATGAAGCCAGTGGGACGGTGGCCCCGACGGTCCAGGAGAAAAAGGTGAAGAAG CGGGTGTCCTTCGCCGACAACCAGGGGCTGGCCCTGACGATGGTCAAAGTGTTCTCCGAG TTCGATGACCCGTTAGATATTCCGCTGAACATCACCGAGCTCCTGGACAGCATCGTGAGC CTGACAACAGCGGAGAGCGAGAGCTTTGTGCTAGATTTCTCGCAGCCATCAGCGGACTAC CTGGACTTCAGAAATCGGCTTCAGACCGACCACGTGTGCCTGGAGAACTGCGTTCTGAAG GACAGGTCCATTGCAGGCACCGTGAAGGTGCAGAACCTCGCGTTCGAGAAGACGGTGAAA GTCCGGATGACCTTTGACACCTGGAAGAGCTTCACAGACTTTCCCTGTTGGTACGTGAAG GACACGTACGCGGGTTCAGACAAGGACACGTTCTCCTTTGACATCAGCTTGCCTGAGAAA ATTCAGTCTTACGAGAGGATGGAGTTCGCCGTGTGCTATGAGTGCAATGGACAGACGTAC TGGGATAGCAACAAAGGCAAAAACTATAGGATCATCCGGGCGGAGCTGCAGTCTACCCAG GGAACAGCCCAGCCGCCAAACGGACCAGATTTTGAAATAGCCTTTGACCAGTTTGGAAGC CCTCGGTGTTCCTACGGTCTGTTTCCGGAGTGGCCTAGTTATTTAGGATACGAGAAGCTT GGGCCATACTACTAG |
| Protein Properties | |
| Number of Residues | 284 |
| Molecular Weight | 32383.0 |
| Theoretical pI | 4.94 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Protein phosphatase 1 regulatory subunit 3B MAVDIECRYSCMAPSLRRERFAFQIAPKPSKPLRPCIQLSGKNEASGTVAPTVQEKKVKK RVSFADNQGLALTMVKVFSEFDDPLDIPLNITELLDSIVSLTTAESESFVLDFSQPSADY LDFRNRLQTDHVCLENCVLKDRSIAGTVKVQNLAFEKTVKVRMTFDTWKSFTDFPCWYVK DTYAGSDKDTFSFDISLPEKIQSYERMEFAVCYECNGQTYWDSNKGKNYRIIRAELQSTQ GTAQPPNGPDFEIAFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY |
| External Links | |
| GenBank ID Protein | AAI48937.1 |
| UniProtKB/Swiss-Prot ID | A6QNP3 |
| UniProtKB/Swiss-Prot Entry Name | PPR3B_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC148936 |
| GeneCard ID | PPP1R3B |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |