| Identification |
|---|
| BMDB Protein ID
| BMDBP01325 |
| Secondary Accession Numbers
| None |
| Name
| Galactoside 3(4)-L-fucosyltransferase |
| Synonyms
|
Not Available
|
| Gene Name
| FUT3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in 3-galactosyl-N-acetylglucosaminide 4-alpha- |
| Specific Function
| May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of sialyl Lewis X and Lewis X/SSEA-1 antigens. It may be involved in blood group Lewis determination. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links. |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| 7q15 |
| SNPs
| FUT3 |
| Gene Sequence
|
>1098 bp
ATGTATCCACCTGGTTGCGCCAAGGTGAAGTGTTCCTGGCACCACTGTCTTCCCGGGCTG
TTGCTGCAGCTGCTTCTGGCTCTGTGCTTCTTCTCTTATCTGCGTATGTCTCAAGAGAAG
CCCAAGCCCAAGCCCATGTGGGTCTCTGAACTGGGGGCCCCTTCCCAGGCCACTGAGGGG
TCCTCCGCCCACCTGCCTCTGCGTGTCCTGCTGTGGACATGGCCATTCAACCAGCCAGTG
GCTCTGTCCCGCTGCTCGGAGTTGTGGCCTGGCACAGCTGACTGCCAGCTGACCGTCAAC
CGAAGCGAGTACCCTCAAGCGGACGCGGTCCTCGTGCACCACCGGGAGGTCAGCCACCGG
CCCCAGATGCAGCTCCCGCCTTCCCCGCGGCCCCCTGGCCAGCGCTGGGTTTGGTTCAGC
ATGGAATCACCCAGCAACTGCTTGAAACTGAAGGACCTAGATGGTTACTTCAACCTCACC
ATGTCCTACCGCCGGGACTCAGATATCTTCATGCCCTACGGCTGGCTCGAGCCGTGGCCC
AGCCAGCCCGTGGAGACGCTGCTCAACATCTCGGCCAAGACCAAGTTGGTGGCCTGGGTG
GTGTCCAACTGGAATACAGACTCTATCAGGGTGCAATACTACAAGCTGCTGAAGCCACAC
CTCCAAGTGGACGTGTACGGACGCTTCCACACGCCACTGCCCCACGCGCTCATGGCCAAG
CAGCTGTCCCAGTACAAGTTCTACCTGGCTTTTGAGAACTCCCTGCACCCCGACTACATC
ACAGAGAAGCTGTGGAAGAACGCCCTGCAGGCATGGGCTGTGCCAGTGGTCCTGGGACCC
AGCCGGGTCAACTATGAACAGTTCCTGCCACCCAAAGCCTTCATCCACGTCGAAGACTTC
CAGAGCCCCAAGGACCTGGCACAGTACTTGCTAGCACTGGACAAGGACTACGCCAGCTAC
CTGAACTACTTCCGCTGGCGGGAGACACTGCGGCCTCGGTCCTTCTCCTGGGCCCTGATG
TTCTGTAAGGCCTGCTGGAAGCTGCAGCAGGAACCCAGGTACCAGACGGTGCCCAGTATC
GCGTCTTGGTTCCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 365 |
| Molecular Weight
| 42654.0 |
| Theoretical pI
| 9.11 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Galactoside 3(4)-L-fucosyltransferase
MYPPGCAKVKCSWHHCLPGLLLQLLLALCFFSYLRMSQEKPKPKPMWVSELGAPSQATEG
SSAHLPLRVLLWTWPFNQPVALSRCSELWPGTADCQLTVNRSEYPQADAVLVHHREVSHR
PQMQLPPSPRPPGQRWVWFSMESPSNCLKLKDLDGYFNLTMSYRRDSDIFMPYGWLEPWP
SQPVETLLNISAKTKLVAWVVSNWNTDSIRVQYYKLLKPHLQVDVYGRFHTPLPHALMAK
QLSQYKFYLAFENSLHPDYITEKLWKNALQAWAVPVVLGPSRVNYEQFLPPKAFIHVEDF
QSPKDLAQYLLALDKDYASYLNYFRWRETLRPRSFSWALMFCKACWKLQQEPRYQTVPSI
ASWFQ
|
| External Links |
|---|
| GenBank ID Protein
| CAA61079.1 |
| UniProtKB/Swiss-Prot ID
| Q11126 |
| UniProtKB/Swiss-Prot Entry Name
| FUT3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X87810 |
| GeneCard ID
| FUT3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
