Showing Protein Profilin-2 (BMDBP01329)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01329 |
| Secondary Accession Numbers | None |
| Name | Profilin-2 |
| Synonyms | Not Available |
| Gene Name | PFN2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in actin binding |
| Specific Function | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 1 |
| Locus | Not Available |
| SNPs | PFN2 |
| Gene Sequence |
>423 bp ATGGCCGGTTGGCAGAGCTACGTGGATAACCTGATGTGCGATGGCTGCTGCCAGGAGGCC GCCATTGTCGGCTACTGCGACGCCAAATACGTCTGGGCAGCCACGGCCGGGGGCGTCTTC CAGAGCATTACGCCAGTAGAAATAGATATGATTGTAGGAAAAGACCGGGAAGGTTTCTTT ACCAATGGTTTGACTCTTGGCGCAAAGAAGTGCTCAGTGATCAGAGATAGCCTATACGTG GACGGTGACTGCACAATGGACATCCGGACAAAGAGTCAAGGTGGGGAGCCAACGTACAAC GTGGCCGTGGGCAGAGCTGGTAGAGTCTTGGTCTTTGTAATGGGAAAAGAAGGGGTCCAT GGAGGCGGATTGAATAAGAAGGCATACTCAATGGCAAAATACTTGAGAGACTCTGGGTTC TAG |
| Protein Properties | |
| Number of Residues | 140 |
| Molecular Weight | 15032.0 |
| Theoretical pI | 7.04 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Profilin-2 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPVEIDMIVGKDREGFF TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH GGGLNKKAYSMAKYLRDSGF |
| External Links | |
| GenBank ID Protein | AAI22617.1 |
| UniProtKB/Swiss-Prot ID | Q09430 |
| UniProtKB/Swiss-Prot Entry Name | PROF2_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC122616 |
| GeneCard ID | PFN2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |