Showing Protein Unconventional myosin-Ic (BMDBP01330)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01330 |
| Secondary Accession Numbers | None |
| Name | Unconventional myosin-Ic |
| Synonyms | Not Available |
| Gene Name | MYO1C |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in actin binding |
| Specific Function | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | Not Available |
| SNPs | MYO1C |
| Gene Sequence |
>3087 bp ATGGAGAGCGCACTGACCGCCCGTGACCGGGTGGGGGTACAGGACTTCGTGCTGCTGGAG AACTTCACCAGCGAGGCCGCCTTCATCGAGAACCTGCGACGGCGCTTCCGGGAGAACCTG ATCTACACCTACATTGGCCCCGTGCTGGTCTCTGTCAACCCCTACCGAGACCTGCAGATC TACAGCCGACAGCACATGGAGCGTTACCGAGGCGTCAGCTTCTATGAGGTTCCACCTCAC CTGTTCGCGGTGGCTGACACTGTCTATCGGGCACTGCGCACGGAGCGCGGGGACCAGGCA GTGATGATCTCTGGGGAAAGCGGGGCAGGCAAGACCGAGGCCACCAAGCGGCTGCTGCAG TTCTATGCCGAGACCTGCCCAGCCCCTGAGCGGGGTGGTGCTGTGCGGGACCGGCTGCTG CAGAGCAACCCGGTGCTGGAGGCCTTTGGCAACGCGAAGACCCTCCGGAACGATAACTCC AGCAGGTTTGGGAAGTACATGGACGTGCAGTTTGACTTCAAGGGTGCCCCCGTGGGTGGC CACATCCTCAGTTACCTCCTGGAGAAGTCCCGGGTGGTGCACCAGAATCACGGGGAGAGG AACTTCCACATCTTCTACCAGCTGCTGGAGGGGGGTGAGGAGGAGACGCTGCGCAGGCTG GGCCTGGAACGGAACCCGCAGAGCTACCTGTACCTGGTGAAGGGCCAGTGCGCCAAAGTC TCCTCCATCAACGACAAGAGTGATTGGAAGGTGGTCAGGAAGGCCCTGACTGTCATCGAC TTCACCGAGGACGAGGTGGAGGACCTGTTAAGCATCGTGGCCAGCGTCCTGCATCTGGGC AACACCCACTTTGCCGCCGATGAGGAGAGCAACGCCCAGGTCACCACCGAGAACCAGCTC AAGTACCTGACCAGGCTCCTTGGTGTGGAAGGCTCAACGCTGCGGGAAGCCCTGACCCAC AGAAAGATCATCGCCAAGGGCGAAGAGCTCCTGAGCCCGCTGAACCTAGAACAGGCTGCA TATGCACGGGACGCCCTCGCCAAGGCTGTGTACAGTCGCACCTTTACCTGGCTGGTCGCG AAGATCAACAGGTCGCTGGCCTCCAAGGATGCCGAGAGCCCCAGCTGGCGGAGCACCACG GTCCTCGGGCTACTGGGCATTTACGGCTTTGAAGTGTTCCAGCACAACAGCTTTGAGCAG TTCTGCATCAATTACTGCAATGAGAAGCTACAGCAGCTCTTCATCGAGCTCACCCTCAAG TCAGAGCAGGAGGAGTATGAGGCCGAGGGCATCGCGTGGGAACCGGTCCAGTATTTCAAC AACAAGATTATCTGTGACCTGGTGGAGGAGAAGTTCAAAGGCATCATCTCCATTTTGGAC GAGGAGTGTCTGCGTCCCGGGGAGGCCACGGACCTGACCTTCCTGGAGAAGCTGGAGGAC ACAATCAAGCAGCATCCACACTTCCTGACGCACAAGCTGGCTGACCAGCGGACCAGGAAA TCTCTGGACCGCGGGGAGTTCCGCCTCCTGCACTATGCCGGGGAGGTGACCTACAACGTG ACCGGGTTTCTGGATAAAAACAACGACCTTCTCTTCCGGAACCTGAAGGAGACCATGTGC AGCTCGGAGAACCCCATCCTGGGCCAGTGCTTCGACCGGAGTGAGCTCAGCAGCAAGAAG CGGCCAGAGACGGTGGCCACCCAGTTCAAGATGAGCCTCCTGGAGCTGGTAGAGATCTTG AAGTCAAAGGAGCCTGCCTATGTCCGCTGCATCAAGCCCAATGACTCCAAGCAGCCCGGC CGCTTTGATGAGGTGCTAATCCGGCACCAGGTGAAGTACCTAGGGCTGATGGAGAACCTG CGTGTGCGCAGAGCCGGCTTTGCCTACCGCCGCAAATACGAGGCTTTCCTGCAGAGGTAC AAGTCACTGTGCCCAGAGACATGGCCCACGTGGACAGGACGCCGCCAGGATGGGGTGACT GTGCTGGTCAGGCACCTGGGCTACAAGCCGGAAGAGTACAAGATGGGCAGGACCAAGATC TTCATCCGCTTCCCCAAGACCCTGTTTGCCACAGAGGACGCCTTGGAGATCCGACGACAG AGCCTGGCCACGAAGATCCAGGCCACCTGGAGGGGCTTTCACTGCCGGCAGAAATTCCTC CGGGTGAAGCGATCAGCGATCTGCATCCAGTCGTGGTGGCGAGGAACGCTGGGCCGGAGG AAGGCGGCCAAGAGGAAGTGGGCGGCACAGACCATCCGGCGGCTCATCCAGGGCTTCATC CTGCGCCATGCGCCCCGTTGCCCTGAGAATGCCTTCTTCGTGGACCATGTGCGCACCTCT TTTCTGCTCAACCTTCGACGGCAGCTGCCCCGGAATATTCTGGACACTTCTTGGCCCACG CCCCCACCTGCCCTGCGTGAGGCCTCAGAGCTGCTGCGGGAGCTGTGCCGGAAGAACATG GTGTGGAAATACTGCCGGAGCATCAGCCCTGAATGGAAGCAGCAGCTGCAGCAAAAGGCC GTTGCGAGTGAGATCTTCAAGGGCAAGAAGGACAATTACCCCCAGAGTGTCCCCAGACTC TTCATCAGCACGCGGCTCGGTGCAGATGAGATCAACCCCAGAGTGCTGCAGGCCCTGGGC TCGGAGCCCATCCAGTACGCCGTGCCCGTCGTGAAGTACGACCGCAAGGGCTACAAGCCG CGCTCCCGGCAGCTGCTGCTGACGCCCAACGCCGTGGTCATTGTGGAGGACGCCAAGGTC AAGCAGAGGATTGAGTACACCAACCTGACCGGAATCTCCGTCAGCAGCCTGAGCGACAGC CTCTTTGTGCTCCACGTGCAGCGTGAGGACAATAAGCAGAAGGGGGACGTGGTGCTGCAG AGTGACCACGTGATCGAGACCCTGACCAAGACAGCCCTCAGCGCTGACCGAGTGAACAAC ATCAACATCAACCAGGGCAGCATCACGTTCGCAGGGGGGCCCGGCAGGGATGGCATCATT GACTTCACACCCGGCTCGGAGCTGCTCATCACCAAGGCCAAGAACGGGCACCTGGCTGTG GTGGCCCCGCGGCTGAACTCGCGGTGA |
| Protein Properties | |
| Number of Residues | 1063 |
| Molecular Weight | 121936.0 |
| Theoretical pI | 9.67 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Myosin-Ic MALQVELIPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSE AAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVA DTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPV LEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIF YQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDE VEDLLSIVASVLHLGNTHFAADEESNAQVTTENQLKYLTRLLGVEGSTLREALTHRKIIA KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVAKINRSLASKDAESPSWRSTTVLGLL DIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIIC DLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTIKQHPHFLTHKLADQRTRKSLDRG EFRLLHYAGEVTYNVTGFLDKNNDLLFRNLKETMCSSENPILGQCFDRSELSDKKRPETV ATQFKMSLLELVEILKSKEPAYVRCIKPNDSKQPGRFDEVLIRHQVKYLGLMENLRVRRA GFAYRRKYEAFLQRYKSLCPETWPTWTGRPQDGVTVLVRHLGYKPEEYKMGRTKIFIRFP KTLFATEDALEIRRQSLATKIQATWRGFHCRQKFLRVKRSAICIQSWWRGTLGRRKAAKR KWAAQTIRRLIQGFILRHAPRCPENAFFVDHVRTSFLLNLRRQLPRNILDTSWPTPPPAL REASELLRELCRKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTR LGADEINPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRIE YTNLTGISVSSLSDSLFVLHVQREDNKQKGDVVLQSDHVIETLTKTALSADRVNNININQ GSITFAGGPGRDGIIDFTPGSELLITKAKNGHLAVVAPRLNSR |
| External Links | |
| GenBank ID Protein | AAA17565.1 |
| UniProtKB/Swiss-Prot ID | Q27966 |
| UniProtKB/Swiss-Prot Entry Name | MYO1C_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | U03420 |
| GeneCard ID | MYO1C |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |