| Identification |
|---|
| BMDB Protein ID
| BMDBP01363 |
| Secondary Accession Numbers
| None |
| Name
| Molybdenum cofactor sulfurase |
| Synonyms
|
Not Available
|
| Gene Name
| MOCOS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in lyase activity |
| Specific Function
| Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 24 |
| Locus
| Not Available |
| SNPs
| MOCOS |
| Gene Sequence
|
>2550 bp
ATGCAAAGCAGACAACCACGGGCACTGCTTCCCCGGTCCCCAGGAACTGTCTATCTTGAC
CATGCAGGAACCACATTGTTCCCCCAGAGCCAGATTACAAGCTTCATGAAAGATCTCATG
GAAAACGTTTATGGTAACCCTCACAGCCAGAACATCAGCAGCAAGCTCACCCATGACACG
GTGGAACAGGTGCGCTTCAGGATCCTGGCGCACTTCCACACCTCCCCGGAGGACTATACG
GTGATTTTCACCTCCGGGAGCACGGCTGCTCTTAAGCTGGTGGCAGAGGCTTTCCCGTGG
GTGTCCCCAGGCCCGGAGGGCAGCGGCAGCTGCTTCTGTTACCTCACCGACAGCCACACG
TCCGTGGTGGGCATGAGGAAGATCACCGCGGCCATGAACGTCTCTTCCATCCCCGTCAGG
CCAGAGGACATGTGGTCGGCCGAGAGACAGGACGCGGCTGCGGCCGGGGACCCCGCCGGC
CAGCCTCCGCATCTCTTCTGCTACCCGGCCCAGAGTAACTTTTCCGGAACCAGATACCCG
CTGTCCTGGATAGGCGAGGTCAAGTCCGGGCGGAGGCGCCCTGCGAGCCGGCCTGGGAAG
TGGTTCGTGCTGCTGGACGCGGCCGCCTTCGTGGGCACCTCGCCTCTGGACCTGTCGGTT
CACCAGGCCGACTTTGTCCCCATCTCCTTCTATAAGATCTTTGGCTTCCCCACTGGCCTG
GGCGCTCTGCTGGTGAATAACCGTTTGGCTGCTCTGCTGAGGAAAACCTACTTCGGAGGA
GGCACGGCCGCTGCGTACCTCGCGGGAGACGACTTCTACGTCCCGAGAGAGTCGGTGGCT
GAGAGGTTTGAAGATGGCACCATCTCCTTTCTTGACGTGATAGCACTAAAACATGGATTT
GATGCCCTAGAGCGCCTCACAGGTGGGATGGAGAGCATCCGGCAGCACACGTTTACCCTG
GCTCAGTACACCTACACTGCCTTGTCTTCCCTGCGGTACCCCAACGGAGCCCCTGTGGTG
CAGATTTATAGTGACTCTGACTTCAGCAGCCCAGAGGTGCAGGGTCCGGTCATCAGCTTC
AACGTGCTCGATGACCATGGGAACGTCGTTGGTTACTCCCAGGTGGATAAAATGGCCAGC
CTTCACAACATCCATGTGCGAACCGGCTGCTTCTGTAACACTGGGGCCTGCCAGAGGCAC
CTGGGGATAAGTGATGAGATGGTGAAGAAGCATCTTCAGGCTGGTCATGTCTGCGGAGAC
GATGTGGACCTCATAGACGGGCAGCCGACGGGCTCTGTGAGGATTTCTTTTGGATACATG
TCTACGCTTGAGGATGCCCAGGCCTTCCTCAGGTTCATCATAGCAACCCGACTGCACTCG
TCTCATGGCCAGCCTCTCCCTCTGGCCACCCCGGGGGAGGCTGGAGCCCCACCAGAAGAC
AGCGAGGCTCAGAACGCCATGCCTGCCGCCCGCGCCAGAGGTAGCTCCTCACCTCAGGAA
GACACTTCCCCACACTCCGGGGTTTGGAACAACTCACCCACCGCTGTGGACGCAGAGGGT
CTGTGTCCGCCCCTGCTGGAGGCCACTGGAACCCAGCAGACCACTTCAGAGAAAGCTGCT
GATGTCCCAGATGGGGACCTCAGGTCACACGTCATCACCAACCTTTTCCTCTACCCAATC
AAGTCCTGTGCAGCATTTGAGGTGATCAGGTGGCCTCTAGGAAGTCAAGGGCTGCTGTAT
GACCGAAGCTGGATGGTTGTGAATCACAACGGCATTTGCCTGAGTCAGAAACAGGAGCCC
CGGCTCTGCCTGATCCAGCCCTTCATTGACCTGCAGCGGAGGATCATGGTCATCAAAGCC
CAAGGGATGGAGCCTATAGAGGTGCCTCTTGAGGAGAACAGTGAGCAGGTTCAGATTTGC
CAAAGCAAAGTCTGTGCGGACAGGGTAAACACATATGATTGTGGAGAAAAAATTTCCAAC
TGGCTGTCAAAGTTTTTTGGCCGTCCCTATCATTTGATCAAACAAAGTTCAGACTTTCAA
AGAAATGCAAAGAAGAAACATGGCAAAGATCAGTCTGCTCACACGACAGCCACCCTTTCT
CTGGTGAATGAGGCACAGTATCTGCTGATAAACAGATCCAGTATTTTGGAACTTCAGCAG
CAATTAAGCACAAGCTGTGAGAATGGCAAAGAAGAATTATTCCCAATGAACAATCTCATC
TCACGGTTCCGTGCCAATATTATTACCAATGGAACAAGGGCTTTTGAAGAAGAGAAATGG
GATGAAATTTCAATTGGTTCCTTGCGTTTCCAGGTTTTGGGACCTTGTCACAGATGTCAG
ATGATTTGCATCGATCAGCAAACTGGACAACGAAACCAAGATGTTTTCCAAAAGCTTTCT
GAGAGGCGAGAGAGAAAGGTGAAGTTTGGAGTGTACCTGATGCATACGTCTTTGGATTTA
TCTTCTCCATGTTACCTCTCCGTAGGATCTCAGGTGCTCCCTCTGCTGAAAGAAAACATG
GAACACCACGATATACCGGCTACCGAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 882 |
| Molecular Weight
| 97205.0 |
| Theoretical pI
| 6.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Molybdenum cofactor sulfurase
MAGGAAHPGAELLPFARFLDSSLQPLVYGYGRGTLHELRAREFGRLAGTVYLDHAGTTLF
PQSQITSFMKDLMENVYGNPHSQNISSKLTHDTVEQVRFRILAHFHTSPEDYTVIFTSGS
TAALKLVAEAFPWVSPGPEGSGSCFCYLTDSHTSVVGMRKITAAMNVSSIPVRPEDMWSA
ERQDAAAAGDPAGQPPHLFCYPAQSNFSGTRYPLSWIGEVKSGRRRPASRPGKWFVLLDA
AAFVGTSPLDLSVHQADFVPISFYKIFGFPTGLGALLVNNRLAALLRKTYFGGGTAAAYL
AGDDFYVPRESVAERFEDGTISFLDVIALKHGFDALERLTGGMESIRQHTFTLAQYTYTA
LSSLRYPNGAPVVQIYSDSDFSSPEVQGPVISFNVLDDHGNVVGYSQVDKMASLHNIHVR
TGCFCNTGACQRHLGISDEMVKKHLQAGHVCGDDVDLIDGQPTGSVRISFGYMSTLEDAQ
AFLRFIIATRLHSSHGQPLPLATPGEAGAPPEDSEAQNAMPAARARGSSSPQEDTSPHSG
VWNNSPTAVDAEGLCPPLLEATGTQQTTSEKAADVPDGDLRSHVITNLFLYPIKSCAAFE
VIRWPLGSQGLLYDRSWMVVNHNGICLSQKQEPRLCLIQPFIDLQRRIMVIKAQGMEPIE
VPLEENSEQVQICQSKVCADRVNTYDCGEKISNWLSKFFGRPYHLIKQSSDFQRNAKKKH
GKDQSAHTTATLSLVNEAQYLLINRSSILELQQQLSTSCENGKEELFPMNNLISRFRANI
ITNGTRAFEEEKWDEISIGSLRFQVLGPCHRCQMICIDQQTGQRNQDVFQKLSERRERKV
KFGVYLMHTSLDLSSPCYLSVGSQVLPLLKENMEHHDIPATE
|
| External Links |
|---|
| GenBank ID Protein
| BAA98138.1 |
| UniProtKB/Swiss-Prot ID
| Q9N0E7 |
| UniProtKB/Swiss-Prot Entry Name
| MOCOS_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB036422 |
| GeneCard ID
| MOCOS |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
