| Identification |
|---|
| BMDB Protein ID
| BMDBP01382 |
| Secondary Accession Numbers
| None |
| Name
| CCN family member 2 |
| Synonyms
|
Not Available
|
| Gene Name
| CCN2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in heparin binding |
| Specific Function
| Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 9 |
| Locus
| Not Available |
| SNPs
| CCN2 |
| Gene Sequence
|
>1050 bp
ATGTCAGCCACCGGCCTGGGCCCGGTCCGCTGCGCCTTCGTGCTCCTGCTCGCCCTCTGC
AGCCGGCCCGCCTCCAGCCAGGACTGCTGCAGCGCCCCGTGCCAGTGCCCTGCCGGCCCG
GCGCCGCGCTGCCCCGCCGGCGTCAGCTTGGTGCTGGACGGCTGCGGCTGCTGCGTGTGC
GCCAAGCAGCTGAGCGAGTTGTGTACCGAGCGCGACCCCTGCGATCCGCACAAGGGCCTC
TTCTGCGACTTCGGCTCCCCAACCAACCGCAAGATCGGCGTGTGCACCGCTAAAGATGGT
GCCCCCTACATTTTCGGAGGAACTGTGTACCAGAGCGGAGAGTCTTTCCAGAGCAGCTGC
AAATACCAGTGCACGTGTCTGGACGGGTCGGTGGGCTGCGTGCCCCTATGCAGCGTGGAC
GTCCGCCTGCCCAGCCCCGACTGCCCCTTCCCACGGAGGGTCAAACTGCCCGGGAAATGC
TGCGAGGAATGGGTGTCCCGTGATGAGAAGGAGCACACCGTGGTCGGCCCTGCGCTGGCA
GCTTACCGGCTGGAAGACACGTTTGGCCCAGACCCAACCATGATCCGAGCCAACTGCCAG
GTCCAGACCACAGAGTGGAGTGCCTATTCCAAGACCTGCGGAATGGGCATCTCCACCCGG
GTTACCAATGACAACGCATTCTGCAGGCTGGAGAAGCAGAGCCGCCTCTGCATGGTCAGG
CCTTGCGAAGCTGACCTGGAGGAGAACATTAAGAAAGGCAAAAAGTGCATCCGGACTCCC
AAAATCTCCAAGCCTATCAAGTTTCAGCTTTCTGGCTGCACCAGCATGAAGACATACCGA
GCTAAATTCTTCGGAGTGTGCACAGACGGGCGGTGCTGCACCCCCCACAGAACCACCACC
CTTCCCGTGGAGTTCAAGTGTCCTGATGGGGAGGTCATGAAGAAGAGCATGATGTTCATC
AAGACCTGTGCCTGCCATTACAACTGCCCCGGAGACAATGACATCTTCGAGTCACTGTAC
TACAGGAAGATGTATGGAGACATGGCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 349 |
| Molecular Weight
| 37924.0 |
| Theoretical pI
| 7.89 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Connective tissue growth factor
MSATGLGPVRCAFVLLLALCSRPASSQDCSAPCQCPAGPAPRCPAGVSLVLDGCGCCRVC
AKQLSELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCVFGGTVYQSGESFQSSC
KYQCTCLDGSVGCVPLCSVDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKEHTVVGPALA
AYRPEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNAFCRLEKQSRLCMVR
PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT
LPVEFKCPDGEVMKKSMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
|
| External Links |
|---|
| GenBank ID Protein
| AAB66596.1 |
| UniProtKB/Swiss-Prot ID
| O18739 |
| UniProtKB/Swiss-Prot Entry Name
| CCN2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF000137 |
| GeneCard ID
| CCN2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
