Identification
BMDB Protein ID BMDBP01403
Secondary Accession Numbers None
Name C-X-C motif chemokine 6
Synonyms Not Available
Gene Name CXCL6
Protein Type Enzyme
Biological Properties
General Function Involved in chemokine activity
Specific Function Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7) (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 6
Locus Not Available
SNPs CXCL6
Gene Sequence
>339 bp
ATGAGACTGCTATCCAGCCGCGCTGCCCGCGTCTCCGGCCCTTCGGGCTCCCTGTGCGCG
CTGCTCGCGCTGCTGCTGCTGACGCCGCCCGGGCCCCTCGCCAGCGCCGGTCCTGTCGCG
GCCGTTGTGAGAGAGCTGCGTTGTGTGTGTTTAACCACCACACCGGGAATTCATCCCAAA
ACGGTCAGTGATCTGCAGGTGATCGCCGCGGGACCGCAGTGCTCCAAGGTGGAAGTGATA
GCCACCTTGAAGAATGGAAGGGAAGTCTGTCTGGACCCAGAAGCTCCTTTGATCAAAAAG
ATCGTTCAGAAAATATTGGACAGTGGAAAGAACAATTGA
Protein Properties
Number of Residues 112
Molecular Weight 11589.0
Theoretical pI 9.62
Pfam Domain Function Not Available
Signals
  • 1-36
Transmembrane Regions
  • 94-114
  • 118-138
  • 140-160
  • 202-222
  • 223-243
  • 269-289
  • 354-374
  • 391-411
  • 428-448
  • 454-474
  • 495-515
Protein Sequence
>C-X-C motif chemokine 6
MRLLSSRAARVSGPSGSLCALLALLLLTPPGPLASAGPVAAVVRELRCVCLTTTPGIHPK
TVSDLQVIAAGPQCSKVEVIATLKNGREVCLDPEAPLIKKIVQKILDSGKNN
GenBank ID Protein AAG35212.1
UniProtKB/Swiss-Prot ID P80221
UniProtKB/Swiss-Prot Entry Name CXCL6_BOVIN
PDB IDs Not Available
GenBank Gene ID AF149249
GeneCard ID CXCL6
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available