Showing Protein Thrombospondin-1 (BMDBP01406)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01406 |
| Secondary Accession Numbers | None |
| Name | Thrombospondin-1 |
| Synonyms | Not Available |
| Gene Name | THBS1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties (By similarity). May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 10 |
| Locus | Not Available |
| SNPs | THBS1 |
| Gene Sequence |
>3513 bp ATGGGGCTGGCCTGGGGACTCGGTGTCCTGCTCCTGTTGCATGCCTGCGGCTCCAACCGC ATTCCAGAGTCTGGGGGAGACAACAGTGTGTTTGACATCTTTGAACTCACCGGAGCTGCC CGCAAGCGGTCTGGGCGCCGACTGGTGAAGGGCCCTGACCCTTCTAGCCCAGCTTTCCGC ATCGAGGATGCCAACCTGATCCCCCCTGTGCCTGACAAGAAGTTCCAAGACCTAGTGGAT GCTGTGCGGGCGGAGAAAGGTTTCCTCCTCCTGGCCTCCCTGAGGCAAATGAAGAAGACC CGGGGTACCCTGCTGGCTGTGGAGCGGAAAGACCACTCTGGCCAGGTCTTCAGCGTGATC TCCAATGGCAAGGCGGGCACCCTGGACCTGAGCCTGACCGTGCAGGGGAAGCAGCATGTG GTGTCGGTGGAAGAAGCACTCCTGGCGACTGGCCAGTGGAAGAGCATCACCCTGTTTGTG CAGGAGGACAGGGCCCAGCTGTACATCGACTGTGAGAAGATGGAGAATGCGGAGCTGGAT GTCCCCATCCAGAGCATCTTCACCAGGGACCTGGCCAGCATCGCCAGGCTCCGCATTGCC AAAGGAGGTGTCAACGACAATTTCCAGGGGGTGCTGCAGAATGTAAGGTTTGTCTTTGGA ACCACACCAGAAGACATCCTCAGGAACAAAGGCTGCTCCAGCTCTACCAGTGTCTTTGTC ACCCTTGACAACAACGTGGTGAATGGGTCCAGCCCTGCCATCCGCACCGACTACATTGGC CACAAGACAAAGGACCTGCAAGCCATCTGTGGCATCTCATGTGACGAGCTGTCCAGCATG GTCCTGGAGCTCAGGGGTCTACGCACCATCGTGACCACGCTGCAGGACAGTATCCGCAAA GTGACCGAAGAGAACAAAGAGCTGGCCAACGAGCTGAGGAGGCCCCCACTCTGCTACCAC AACGGAGTGCAGTACAGGACTGGCGACGAGTGGACGGTGGACAGCTGCACTGAGTGTCGC TGCCAGAACTCAGTTACCATCTGCAAAAAAGTGTCCTGTCCCATCATGCCCTGCTCCAAT GCCACAGTTCCGGATGGAGAATGCTGCCCACGGTGCTGGCCCAGCGACTCTGCAGACGAT GGCTGGTCCCCGTGGTCTGAGTGGACCTCTTGCTCTGTGACCTGTGGCAATGGAATCCAG CAGCGTGGCCGCTCCTGCGACAGCCTCAACAACAGATGCGAGGGCTCCTCTGTGCAGACG CGGACCTGCCACATCCAGGAGTGTGACAAGAGATTTAAACAGGATGGCGGCTGGAGCCAC TGGTCCCCATGGTCATCTTGCTCCGTAACATGTGGAGACGGTGTGATCACAAGGATCCGG CTCTGCAACTCCCCCAGCCCCCAGATGAATGGGAAGCCATGTGAGGGCAAAGCCCGGGAG ACCAAAGCCTGCCAGAAAGACTCCTGCCCCATCAATGGAGGCTGGGGACCTTGGTCACCA TGGGACATCTGTTCTGTCACCTGTGGAGGAGGGGTACAGAAACGTAGCCGGCTCTGCAAC AACCCCAAACCCCAGTTTGGAGGCAAGGACTGCGTTGGTGATGTGACAGAAAACCAGATC TGCAACAAGCAGGACTGTCCCATTGACGGATGCCTGTCCAATCCCTGCTTTGCTGGTGTC CAGTGTACCAGCTACCCTGATGGCAGCTGGAAGTGTGGTGCCTGTCCCCCAGGCTATAGT GGAGATGGAGTCGAGTGCAAAGACGTTGATGAGTGCAAAGAAGTCCCTGATGCCTGCTTC AACCACAATGGAGAGCACAGGTGTGAGAACACAGACCCCGGCTACAACTGCCTGCCCTGC CCACCGCGCTTCACTGGCTCGCAGCCCTTTGGCCGGGGCGTGGAACATGCCACCGCCAAC AAGCAGGTATGCAAGCCCCGAAACCCCTGCACAGACGGGACACACGACTGCAACAAGAAC GCCAAGTGCAACTACCTGGGCCACTACAGCGACCCCATGTACCGCTGCGAGTGCAAGCCT GGCTACGCCGGCAACGGCATCATCTGCGGGGAGGACACAGACCTGGACGGCTGGCCCAAT GAGGACCTGCTGTGCGTGGCCAACGCAACTTACCACTGCAGAAAGGATAATTGCCCCAAC CTTCCCAACTCAGGGCAGGAAGACTATGACAAGGATGGAATCGGCGATGCCTGCGATGAT GACGATGACAATGATAAGATTCCAGATGACAGGGACAACTGTCCATTCCATTACAACCCA GCCCAGTACGACTATGACAGAGATGACGTGGGAGACCGCTGTGACAACTGCCCCTACAAC CACAACCCAGACCAGGCTGACACAGATAACAATGGGGAAGGAGACGCCTGTGCAGCTGAC ATTGATGGGGACAGTATCCTCAATGAACGGGACAACTGCCAGTATGTCTACAATGTGGAC CAGAAAGACACTGACATGGACGGGGTTGGTGATCAGTGTGACAACTGCCCCCTGGAACAC AATCCAGACCAGCTCGACTCTGACTCGGACCGCATTGGAGACACCTGTGACAACAATCAG GATATTGATGAAGACGGCCACCAGAACAATCTGGACAACTGTCCCTACGTGCCCAACGCC AACCAGGCTGACCATGACAAGGATGGCAAAGGCGATGCCTGTGACCATGATGACGACAAT GATGGCATTCCTGATGACCGGGACAACTGCAGGCTGGTGCCCAATCCTGACCAGAAGGAC TCTGATGGTGATGGTCGAGGTGATGCTTGCAAAGATGATTTTGACCAGGACAAGGTGCCA GACATTGATGACATCTGTCCCGAAAATGTTGATATCAGTGAGACTGATTTCCGCCGATTC CAGATGATTCCTCTAGATCCCAAAGGGACATCCCAGAATGACCCTAACTGGGTTGTACGC CATCAGGGTAAAGAACTCGTCCAGACTGTCAACTGTGACCCTGGACTTGCTGTAGGTTAT GACGAATTTAACGCCGTGGACTTCAGTGGCACCTTCTTCATCAACACCGAGAGGGATGAC GACTATGCCGGCTTTGTGTTTGGCTACCAGTCCAGCAGCCGCTTCTATGTTGTGATGTGG AAGCAAGTCACTCAGTCCTACTGGGACACCAACCCCACGAGGGCTCAGGGGTACTCTGGA CTTTCCGTGAAGGTTGTAAACTCCACCACGGGGCCTGGCGAGCACCTGCGGAATGCCCTG TGGCACACAGGAAACACCTCTGGCCAGGTGCGCACACTGTGGCATGACCCTCGTCACATT GGCTGGAAAGATTTCACTGCCTACAGATGGCATCTGAGCCACAGGCCAAAGACAGGTTTC ATCAGAGTGGTAATGTATGAAGGGAAGAAAATCATGGCTGACTCAGGACCCATCTATGAC AAAACCTATGCTGGTGGGAGGCTAGGCTTGTTCGTCTTCTCTCAAGAAATGGTGTTCTTC TCCGACCTGAAATATGAATGCAGAGACTCCTAA |
| Protein Properties | |
| Number of Residues | 1170 |
| Molecular Weight | 129534.0 |
| Theoretical pI | 4.54 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Thrombospondin-1 MGLAWGLGVLLLLHACGSNRIPESGGDNSVFDIFELTGAARKRSGRRLVKGPDPSSPAFR IEDANLIPPVPDKKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAVERKDHSGQVFSVI SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSIFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVFV TLDNNVVNGSSPAIRTDYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELANELRRPPLCYHNGVQYRTGDEWTVDSCTECRCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSVTCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGKARE TKACQKDSCPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPKPQFGGKDCVGDVTENQI CNKQDCPIDGCLSNPCFAGVQCTSYPDGSWKCGACPPGYSGDGVECKDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGRGVEHATANKQVCKPRNPCTDGTHDCNKN AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLLCVANATYHCRKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDSILNERDNCQYVYNVDQKDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDQDKVPDIDDICPENVDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTSGQVRTLWHDPRHIGWKDFTAYRWHLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDS |
| External Links | |
| GenBank ID Protein | BAA21115.1 |
| UniProtKB/Swiss-Prot ID | Q28178 |
| UniProtKB/Swiss-Prot Entry Name | TSP1_BOVIN |
| PDB IDs | |
| GenBank Gene ID | AB005287 |
| GeneCard ID | THBS1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |