| Identification |
|---|
| BMDB Protein ID
| BMDBP01407 |
| Secondary Accession Numbers
| None |
| Name
| Fibroblast growth factor 5 |
| Synonyms
|
Not Available
|
| Gene Name
| FGF5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in growth factor activity |
| Specific Function
| Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| FGF5 |
| Gene Sequence
|
>813 bp
ATGAGCTTGTCCTTCCTCCTCCTCCTCTTCCTCAGCCACCTGATCCTCAGCGCCTGGGCT
CAAGGGGAGAAGCGCCTCGCACCCAAAGGGCAGCCCGGACCTGCTGCCACCGAGAGGAAC
CCGGGAGGCGCCAGCAGCCGCCGGAGCAGCAGTAGCACCGCGACTTCCTCTTCTTCCCCT
GCCTCCTCCTCCTCCGCGGCTTCTCGGGGCGGCCCAGGAAGCAGCTTGGAGCAGAGCAGC
TTCCAGTGGAGCCCCTCGGGGCGCCGGACCGGCAGCCTCTACTGCAGAGTGGGCATCGGT
TTCCATCTGCAGATCTACCCGGATGGCAAAGTCAACGGCTCCCACGAAGCCAATATGTTA
AGTATTTTGGAAATATTTGCTGTGTCTCAGGGGATTGTAGGAATACGAGGAGTTTTCAGC
AACAAATTTTTAGCGATGTCAAAAAAAGGAAAACTCCATGCAAGTGCCAAATTTACAGAT
GACTGCAAGTTCAGGGAGCGATTTCAAGAAAACAGCTATAATACCTATGCCTCTGCGATA
CACAGAACTGAAAAGACGGGGCGGGAGTGGTACGTGGCCCTGAACAAGAGGGGGAAGGCT
AAACGGGGCTGTAGCCCCCGGGTTAAACCTCAGCACGTCTCTACCCACTTTCTGCCAAGA
TTCAAGCAATTGGAGCAGCCGGAACTTTCTTTCACAGTTACTGTTCCCGAAAAGAAAAAG
CCACCTAATCCTGTCAAGCCAAAGGTTCCCCTTTCCGCACCTCGGAGAAGTCCTAACACC
GTGAAATACAGACTCAAGTTTCGCTTTGGTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 270 |
| Molecular Weight
| 29641.0 |
| Theoretical pI
| 11.33 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 113-133
- 138-158
- 214-234
- 237-257
- 379-399
- 415-435
- 453-473
- 519-539
|
| Protein Sequence
|
>Fibroblast growth factor 5
MSLSFLLLLFLSHLILSAWAQGEKRLAPKGQPGPAATERNPGGASSRRSSSSTATSSSSP
ASSSSAASRGGPGSSLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANML
SILEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAI
HRTEKTGREWYVALNKRGKAKRGCSPRVKPQHVSTHFLPRFKQLEQPELSFTVTVPEKKK
PPNPVKPKVPLSAPRRSPNTVKYRLKFRFG
|
| External Links |
|---|
| GenBank ID Protein
| ABK34274.1 |
| UniProtKB/Swiss-Prot ID
| A0MTF4 |
| UniProtKB/Swiss-Prot Entry Name
| FGF5_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| EF042192 |
| GeneCard ID
| FGF5 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
