Identification
BMDB Protein ID BMDBP01408
Secondary Accession Numbers None
Name Platelet factor 4
Synonyms Not Available
Gene Name PF4
Protein Type Enzyme
Biological Properties
General Function Involved in chemokine activity
Specific Function Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 6
Locus Not Available
SNPs PF4
Gene Sequence Not Available
Protein Properties
Number of Residues 88
Molecular Weight 9523.0
Theoretical pI 6.49
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 450-470
  • 479-499
  • 520-540
  • 551-571
  • 594-614
  • 638-658
  • 663-683
Protein Sequence
>Platelet factor 4
ESSFPATFVPLPADSEGGEDEDLQCVCLKTTSGINPRHISSLEVIGAGTHCPSPQLLATK
KTGRKICLDQQRPLYKKILKKLLDGDES
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P02777
UniProtKB/Swiss-Prot Entry Name PLF4_BOVIN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID PF4
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available