Showing Protein Membrane-associated progesterone receptor component 1 (BMDBP01473)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01473 |
| Secondary Accession Numbers | None |
| Name | Membrane-associated progesterone receptor component 1 |
| Synonyms | Not Available |
| Gene Name | PGRMC1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in heme binding |
| Specific Function | Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | Not Available |
| Locus | Not Available |
| SNPs | PGRMC1 |
| Gene Sequence |
>585 bp ATGGCTGCCGAGGATGTGGCGGCGACCGGCGCAGACACGAGCGAGCTCGAGAGCGGCGGG CTGCTGCAAGAGATTTTCACGTCGCCGCTCAACCTGCTGCTCCTTGGCCTTTGCATCTTT CTGCTCTACAAGATCGTGCGCGGGGACCAGCCGGCGGCCAGCGATAGCGACGACGACGAG CCGCCCCCGCTGCCCCGCCTTAAGCGGCGCGACTTCACCCCTGCCGAGCTGCGGCGCTTC GACGGCGTACAGGACCCGCGTATACTCATGGCCATCAATGGCAAGGTGTTCGACGTAACC AAAGGCCGCAAGTTCTACGGGCCTGAGGGGCCGTATGGAGTCTTTGCTGGAAGAGATGCA TCCAGAGGCCTTGCCACCTTTTGCCTGGATAAGGAAGCGCTGAAGGATGAGTACGATGAC CTTTCCGACCTCACTCCTGCCCAGCAGGAGACCCTGAGTGACTGGGACTCTCAGTTCACT TTCAAGTACCATCATGTGGGCAAACTGCTGAAGGACGGGGAGGAGCCCACCGTGTACTCA GACAAGGAGGAGCCAAAAGATGAGAGCACTCGGAAGAATGATTAA |
| Protein Properties | |
| Number of Residues | 194 |
| Molecular Weight | 21622.0 |
| Theoretical pI | 4.33 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Membrane-associated progesterone receptor component 1 MAAEDVAATGADTSELESGGLLQEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASDSDDDE PPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDA SRGLATFCLDKEALKDEYDDLSDLTPAQQETLSDWDSQFTFKYHHVGKLLKDGEEPTVYS DKEEPKDESTRKND |
| External Links | |
| GenBank ID Protein | AAI18445.1 |
| UniProtKB/Swiss-Prot ID | Q17QC0 |
| UniProtKB/Swiss-Prot Entry Name | PGRC1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC118444 |
| GeneCard ID | PGRMC1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |