| Identification |
|---|
| BMDB Protein ID
| BMDBP01571 |
| Secondary Accession Numbers
| None |
| Name
| Solute carrier family 22 member 16 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC22A16 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 9 |
| Locus
| Not Available |
| SNPs
| SLC22A16 |
| Gene Sequence
|
>906 bp
ATGGGGTCCAGCAACTTGGAGCTGATTTTTGACAGCGTGGGGCACTTCGGCAGATACCAA
ATATTCCTCTATTTTATATGTGCCTTCCAAAATATCTCTTGTGGTATCCACTACTTGGCT
TCTGTGTTCTTGTCAGTGTCCCCCCAGCATACCTGTAGGCCCCCAGGCAATGTGAGTCAG
GTTCTTTTCCAAGACCTCTCTACTTGGCAGTTGGAGGACATCTGGACCCAGTTCTCCGTA
GGCCGTGAGGATCGCATTCTCGTGCAGCTGCAGGATGGGGCGATCTGGGAGCTTACCAGC
TGTCAGAGGTTCCGGAGGGATGACCAGTCGAGCCTGGACTATGAGTACAGCGGCCAGAAG
AGCAGCTTCCCTTGCTTGGATGGCTACATCTACGACAGAAGCAAGTGGCTCAGCACTGTG
GTGACCCAGTGGGACCTGGTGTGTAACCGAGAGTGGTTTGGAAGGCTGATCCAGCCCACG
TTTATGTTTGGAGTCCTGCTGGGAGCAGTGATCTTTGGCTACCTCTCCGACAGGGCAGGA
AGACGACTTGTTTTGTGGGCCTCAAGCACCGGTGTATTTTTGTTTGGCATAGCGGCGGCA
TTCACATTTGATTATTACAGCTTCATAGTCGCACGCTTTCTTCTTGCTATCTCTGGAAGT
GGCTATCTCGTGGTGGTGTTTGTCTATGTGACAGAATTTGTCGGCATGAAGTCTCGGACG
TGGGCGTCCATCCACTTGCATTCCTTTTTTTGCTTTTGGAACCATGGTGGTGGCTTTGAC
GGGCTACTTCGTCAGGACCTGGTGGATCTATCAGATAGTCCTCTCCTCCGTGACTGTCCC
CTTTGTCTTGTGCTGTTGGATGCTCCCAGAGACACCTTTTTGGCTTATCTCAGGGGGAAA
ATATGA
|
| Protein Properties |
|---|
| Number of Residues
| 572 |
| Molecular Weight
| 64355.0 |
| Theoretical pI
| 6.59 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 21-41
- 156-176
- 183-203
- 208-228
- 244-264
- 268-288
- 359-379
- 389-409
- 416-436
- 441-461
- 476-496
- 503-523
|
| Protein Sequence
|
>Solute carrier family 22 member 16
MGSSNLELIFDSVGHFGRYQIFLYFICAFQNISCGIHYLASVFLSVSPQHTCRPPGNVSQ
VLFQDLSTWQLEDIWTQFSVGREDRILVQLQDGAIWELTSCQRFRRDDQSSLDYEYSGQK
SSFPCLDGYIYDRSKWLSTVVTQWDLVCNREWFGRLIQPTFMFGVLLGAVIFGYLSDRAG
RRLVLWASSTGVFLFGIAAAFTFDYYSFIVARFLLAISGSGYLVVVFVYVTEFVGMKSRT
WASIHLHSFFAFGTMVVALTGYFVRTWWIYQIVLSSVTVPFVLCCWMLPETPFWLISGGK
YEEAQKVIDTMAKWNRTRPCKLSEILSLDHDGSAGNKPSQVEKHTLSELFYDWSIGTRTL
ILWLIWFTGCLGFYTFSLNSVHLGGSEYLNLFLMGVVEIPAYVLVCLGMDRVGRRNILIF
SLLSSAVTSGVIMVIPKDYHVWLVVASMAGKFFIGAAFGLIYLYTAELYPTIVRSLAVGS
GSTVGRVGSIVAPLCIYLSSVWIFMPQLLVGTLALVSGVLTFLLPETLRRPLTTTWEETE
KESSSGKLLSTTSNTVLENVTVENSEDSSLNK
|
| External Links |
|---|
| GenBank ID Protein
| AAI18254.1 |
| UniProtKB/Swiss-Prot ID
| Q17QN9 |
| UniProtKB/Swiss-Prot Entry Name
| S22AG_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC118253 |
| GeneCard ID
| SLC22A16 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
