Showing Protein Cyclic AMP-responsive element-binding protein 1 (BMDBP01589)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01589 |
| Secondary Accession Numbers | None |
| Name | Cyclic AMP-responsive element-binding protein 1 |
| Synonyms | Not Available |
| Gene Name | CREB1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in protein dimerization activity |
| Specific Function | Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 2 |
| Locus | Not Available |
| SNPs | CREB1 |
| Gene Sequence |
>978 bp ATGGAATCTGGAGCAGAGAACCAGCAGAGTGGAGATGCAGCTGTAACAGAAGCTGAAAGC CAGCAAATGACAGTTCAAGCCCAGCCACAGATTGCCACATTAGCCCAGGTATCTATGCCA GCAGCTCACGCAACATCATCTGCTCCCACCGTAACTTTAGTACAGCTGCCCAATGGGACC AAGGTTCAAGTCCATGGAGTTATTCAGGCGGCCCAGCCATCAGTTATTCAGTCTCCACAA GTCCAGACAGTTCAGATTTCAACTATTGCAGAAAGTGAAGATTCACAGGAGTCAGTGGAT AGTGTAACCGATTCCCAAAAACGAAGAGAGATTCTTTCAAGGAGGCCTTCCTACAGGAAA ATTTTGAATGACTTATCTTCTGATGCACCAGGAGTGCCAAGGATTGAAGAAGAGAAATCT GAAGAGGAGACTTCAGCACCTGCCATCACCACTGTCACGGTGCCAACTCCGATTTATCAG ACTAGCAGTGGACAGTATATTGCCATTACCCAAGGAGGAGCAATACAACTGGCTAACAAT GGTACTGATGGGGTACAGGGCCTGCAGACATTAACCATGACCAATGCAGCTGCCACTCAG CCAGGTACTACCATCCTGCAGTATGCACAGACCACTGATGGACAGCAAATCCTAGTGCCC AGCAACCAAGTTGTTGTTCAAGCTGCCTCTGGAGATGTACAGACATACCAGATTCGCACA GCGCCCACTAGCACCATTGCCCCTGGAGTTGTTATGGCGTCTTCCCCAGCACTTCCTACA CAGCCTGCTGAAGAAGCGGCGCGAAAGAGAGAGGTTCGCCTCATGAAGAACAGGGAAGCA GCACGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTCTAGAAAACAGAGTGGCA GTGCTTGAAAATCAAAACAAGACACTGATTGAGGAGCTAAAAGCACTTAAGGACCTTTAC TGCCACAAATCAGATTAA |
| Protein Properties | |
| Number of Residues | 325 |
| Molecular Weight | 34877.0 |
| Theoretical pI | 4.93 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
|
| Protein Sequence |
>Cyclic AMP-responsive element-binding protein 1 MESGAENQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQ TVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRK ILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANN GTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRT APTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVA VLENQNKTLIEELKALKDLYCHKSD |
| External Links | |
| GenBank ID Protein | CAA40347.1 |
| UniProtKB/Swiss-Prot ID | P27925 |
| UniProtKB/Swiss-Prot Entry Name | CREB1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | X57031 |
| GeneCard ID | CREB1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |