| Identification |
|---|
| BMDB Protein ID
| BMDBP01595 |
| Secondary Accession Numbers
| None |
| Name
| Ribonuclease H2 subunit A |
| Synonyms
|
Not Available
|
| Gene Name
| RNASEH2A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Replication, recombination and repair |
| Specific Function
| Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| RNASEH2A |
| Gene Sequence
|
>900 bp
ATGGATCTCAGCGAGCTGGAAAGAGACAATACGGGCCGCTGTCGCCTGAGTTCGCCTGTG
CCTCCTGTGTGCCTCAAAGAGCCCTGCGTCCTGGGCGTCGATGAAGCAGGCCGGGGCCCG
GTGCTGGGCCCCATGGTCTATGCTATCTGCTATTGTCCCCTGTCCCGCCTGGAGGATCTG
GAGGCTCTGAAAGTGGCAGACTCAAAGACCCTGTCGGAGAGCGAGCGGGACAGGCTCTTT
GCGAAAATGGAGGAGGACGGGGACTTTGTGGGCTGGGCACTGGACGTGCTGTCTCCAAAC
CTCATCTCTACCAGCATGCTTGGGCGGGTGAAATACAACCTGAACGCCCTCTCTCATGAT
ACAGCCACTGGGCTAGTGCAGTTTGCGTTGGACCAGGGTGTGAACGTGGCCCAGGTGTTT
GTGGACACCGTGGGGCTCCCAGAGACATACCAGGAACGATTGCAGCAGCGTTTCCCTGGC
ATTGAGGTGACAGTCAAGGCCAAGGCAGATGCCCTCTACCCTGTGGTCAGTGCTGCCAGT
ATCTGTGCCAAGGTGGCCCGAGACCAGGCTGTGAAGAACTGGAAGTTTGTGGAGAAACTG
CAGGACCTGGACACTGATTATGGCTCGGGCTACCCTAATGATCCCAAGACGAAAGCCTGG
TTGAGGAAGCACGTGGACCCTGTGTTCGGCTTCCCCCAGTTTGTCCGCTTCAGCTGGCGC
ACAGCCCAGAGCATCCTGGAGAGTGAGGCGGAAGACGTGAAGTGGGAGGACTCAGAGACT
GGGGATCCGAAGGGACCTGGGAAGATCAAGTCCTACTTCAGTGAAAGCCCCCAAACCTGC
CTCCGCCTCCCCCATCGGTACTTCCAGGAGCGGGGCCTGGAGTCAGCCACTGTCCTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 299 |
| Molecular Weight
| 33300.0 |
| Theoretical pI
| 4.81 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ribonuclease H2 subunit A
MDLSELERDNTGRCRLSSPVPPVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLEDL
EALKVADSKTLSESERDRLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNALSHD
TATGLVQFALDQGVNVAQVFVDTVGLPETYQERLQQRFPGIEVTVKAKADALYPVVSAAS
ICAKVARDQAVKNWKFVEKLQDLDTDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWR
TAQSILESEAEDVKWEDSETGDPKGPGKIKSYFSESPQTCLRLPHRYFQERGLESATVL
|
| External Links |
|---|
| GenBank ID Protein
| AAI09683.1 |
| UniProtKB/Swiss-Prot ID
| Q2TBT5 |
| UniProtKB/Swiss-Prot Entry Name
| RNH2A_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109682 |
| GeneCard ID
| RNASEH2A |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
