| Identification |
|---|
| BMDB Protein ID
| BMDBP01608 |
| Secondary Accession Numbers
| None |
| Name
| Prostaglandin E2 receptor EP4 subtype |
| Synonyms
|
Not Available
|
| Gene Name
| PTGER4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in prostaglandin E receptor activity |
| Specific Function
| Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 20 |
| Locus
| Not Available |
| SNPs
| PTGER4 |
| Gene Sequence
|
>1479 bp
ATGTCCATTCCCGGGACCAATGCATCATCCTCCCAGGCCTCCAACCCACTGAACAGCCCA
GTGACCATCCCGGCGGTGATGTTCATCTTCGGGGTCGTGGGCAACCTGGTGGCCATCGTG
GTGCTCTGTAAATCGCGCAAGGAGCAGAAGGAGACAACTTTCTACACACTGGTATGCGGG
CTGGCGGTCACCGACCTGCTGGGTACGTTGCTGGTGAGCCCGGTGACCATCGCCACCTAC
TTGAAGGGCCAATGGCCCGGGGGCCACGCGCTGTGCGAATACAGCACCTTCATCCTGCTC
TTCTTTGGCCTGTCGGGGCTCAGCATCATCTGTGCGATGAGTATTGAGCGCTACCTGGCC
ATCAACCACGCCTACTTCTACAGCCACTACGTGGACAAGCGGCTGGCGGGGCTCACGCTC
TTCGCGGTCTACGCGTCCAACGTGCTCTTCTGCGCGCTGCCCAGCATGGGCCTGGGCAGT
TCGCGGCTGCAGTACCCGGCCACCTGGTGCTTCATCGACTGGACCACCAACGTGACAGCG
CACGCCGCCTTCTCCTACATGTATGCGGGCTTCAGTTCCTTCCTCATCCTCGCCACCGTG
CTCTGCAACGTGCTCGTGTGCGGCGCGCTGCTCCGCATGCACCGCCAGTTCATGCGCCGC
ACCTCGCTGGGCACCGAGCAGCAGCACCACGCGGCCGCCGCCGCCGTCGCCTTGGCCCCG
ACAGCCTGCCGGGCTCCCCCGGCCGCCTCCTCCCCCGCCCTGCCGCGCCTCAGCGACTTT
CGCCGCCGCCGGAGCTTCCGCCGCATCGCGGGCGCCGAGATCCAGATGGTCATCTTACTC
ATCGCCACCTCTCTGGTGGTGCTCATCTGCTCCATCCCGCTTGTGGTGCGAGTGTTCGTC
AACCAGTTATATCGGCCACAACTGGAGCCAGTCATCGGCAAAAACCCTGATTTGCAGGCC
ATCCGAATTGCTTCTGTGAGCCCCATTCTGGACCCCTGGATATACATCCTCCTGCGGAAG
ACAGTGCTCAGTAAAGCCATAGAGAAGATCAAATGCCTCTTCTGCCGCATCGGCGGGTCG
CGCCGGGAGCGTTCGGGGCCGCACTGCTCAGACAGCAGAAGGACGTCCTCCGCCGTGTCC
GGCCACTCCCGCTCCTTCCTCTCCCGGGAGCTGAAAGAGATCAGCAGCACGTCGCAGACC
CTCCTGTACACGCCAGAACTCAGTGAAAACGGCCTCGGGGGAGGCAGGAATCTGCTGCCA
GGTGTGCCCGGCGTGGGCCTGACCCAAATAGACAGCACGTCGCTTAGGACTCTGCGAATA
TCGGAGACCTCAGACTCCTCACAGGGGCAGGACTCGGAGAGCTTCTTACTGGTGGACGAG
GTTGGCGGGAGCTGCAGGGCTGGGCCCGCCCCTAAGGGGAGCTCCCTGCAAGTCACGTTT
CCCAGTGAAACGCTGAACTTATCAGAAAAATGTATATAG
|
| Protein Properties |
|---|
| Number of Residues
| 492 |
| Molecular Weight
| 53298.0 |
| Theoretical pI
| 9.29 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 20-43
- 56-79
- 97-115
- 136-160
- 185-211
- 274-301
- 319-338
|
| Protein Sequence
|
>Prostaglandin E2 receptor EP4 subtype
MSIPGTNASSSQASNPLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYLKGQWPGGHALCEYSTFILLFFGLSGLSIICAMSIERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPSMGLGSSRLQYPATWCFIDWTTNVTA
HAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQQHHAAAAAVALAP
TACRAPPAASSPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFV
NQLYRPQLEPVIGKNPDLQAIRIASVSPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGS
RRERSGPHCSDSRRTSSAVSGHSRSFLSRELKEISSTSQTLLYTPELSENGLGGGRNLLP
GVPGVGLTQIDSTSLRTLRISETSDSSQGQDSESFLLVDEVGGSCRAGPAPKGSSLQVTF
PSETLNLSEKCI
|
| External Links |
|---|
| GenBank ID Protein
| AAN01235.1 |
| UniProtKB/Swiss-Prot ID
| Q8MJ08 |
| UniProtKB/Swiss-Prot Entry Name
| PE2R4_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF539403 |
| GeneCard ID
| PTGER4 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
