Showing Protein Selenoprotein K (BMDBP01622)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01622 |
| Secondary Accession Numbers | None |
| Name | Selenoprotein K |
| Synonyms | Not Available |
| Gene Name | SELENOK |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in selenium binding |
| Specific Function | Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection of cells from ER stress-induced apoptosis. Protects cells from oxidative stress when overexpressed in cardiomyocytes (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 22 |
| Locus | Not Available |
| SNPs | SELENOK |
| Gene Sequence |
>279 bp ATGGTTTACATCTCGAATGGACAAGTGTTGGACAGCAGGAGTCAGTCCCCATGGAGATTA TCTTTTATAACAGATTTCTTCTGGGGAATAGCTGAGTTTGTGGTTTTGTTTTTCAGAACT CTGCTTCAACAAGATGTGAAAAAGAGAAGAGGCTACGGAAGCTCATCTGATTCCAGATAT GATGACGGAAGAGGGCCACCAGGAAACCCCCCCAGAAGAAGAATGGGTCGAATTAATCAT CTGCAGGGCCCTAATCCTCCTCCAATGGCCGGTGGATGA |
| Protein Properties | |
| Number of Residues | 95 |
| Molecular Weight | 10805.0 |
| Theoretical pI | 11.61 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Selenoprotein K MVYISNGQVLDSRSQSPWRLSFITDFFWGIAEFVVLFFRTLLQQDVKKRRGYGSSSDSRY DDGRGPPGNPPRRRMGRINHLQGPNPPPMAGGUGR |
| External Links | |
| GenBank ID Protein | AAI08151.1 |
| UniProtKB/Swiss-Prot ID | Q32PE3 |
| UniProtKB/Swiss-Prot Entry Name | SELK_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC108150 |
| GeneCard ID | SELENOK |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |