Showing Protein Mitochondrial 2-oxoglutarate/malate carrier protein (BMDBP01814)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01814 |
| Secondary Accession Numbers | None |
| Name | Mitochondrial 2-oxoglutarate/malate carrier protein |
| Synonyms | Not Available |
| Gene Name | SLC25A11 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in binding |
| Specific Function | Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Involved in the regulation of apoptosis. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | Not Available |
| SNPs | SLC25A11 |
| Gene Sequence |
>945 bp ATGGCGGCGACGGCGAGTCCCGGGGCTTCTGGGATGGACGGGAAGCCCCGTACCTCCCCT AAGTCCGTCAAGTTCCTGTTTGGGGGCCTGGCCGGGATGGGAGCTACAGTTTTTGTGCAG CCCTTGGACCTGGTGAAGAACCGGATGCAGCTGAGTGGGGAAGGAGCCAAGACACGAGAG TACAAAACCAGCTTCCATGCCCTCATCAGCATCCTGAGGGCAGAAGGGCTTAGGGGCATT TACACCGGGCTATCAGCTGGCCTGTTGCGCCAGGCCACCTACACTACTACTCGTCTTGGT ATCTATACTGTGCTGTTTGAGCGCCTGACTGGGGCTGATGGTACACCCCCTGGCTTTCTG CTGAAGGCTGTGATTGGCATGACTGCAGGTGCAACTGGTGCCTTTGTGGGAACACCAGCT GAAGTGGCTCTTATCCGCATGACCGCTGATGGCCGGCTTCCAGTTGACCAGCGTCGTGGC TACAAAAACGTGTTTAATGCCCTGTTTCGAATTGTCCAGGAAGAGGGGGTCCCCACACTA TGGAGGGGCTGCATCCCTACCATGGCTCGGGCTGTCGTCGTCAACGCTGCCCAGCTTGCC TCCTACTCCCAGTCCAAGCAGTTTTTACTGGACTCAGGCTACTTCTCTGACAACATCCTG TGCCACTTCTGTGCTAGCATGATCAGTGGCCTGGTCACCACTGCTGCCTCCATGCCCGTG GACATTGTCAAGACCCGGATCCAGAACATGCGGATGATTGACGGGAAGCCAGAATACAAG AATGGGCTGGATGTGCTGGTGAAGGTCGTGCGCTACGAGGGCTTCTTCAGCCTGTGGAAG GGCTTTACACCATACTATGCCCGCCTGGGCCCCCACACTGTCCTCACTTTCATCTTCTTG GAGCAGATGAACAAGGCCTACAAGCGTCTCTTCCTCAGTGGCTGA |
| Protein Properties | |
| Number of Residues | 314 |
| Molecular Weight | 34172.0 |
| Theoretical pI | 10.35 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
|
| Protein Sequence |
>Mitochondrial 2-oxoglutarate/malate carrier protein MAATASPGASGMDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTRE YKTSFHALISILRAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTL WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV DIVKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL EQMNKAYKRLFLSG |
| External Links | |
| GenBank ID Protein | CAA46906.1 |
| UniProtKB/Swiss-Prot ID | P22292 |
| UniProtKB/Swiss-Prot Entry Name | M2OM_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | X66115 |
| GeneCard ID | SLC25A11 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |