Identification
BMDB Protein ID BMDBP01817
Secondary Accession Numbers None
Name Alpha-2A adrenergic receptor
Synonyms Not Available
Gene Name ADRA2A
Protein Type Enzyme
Biological Properties
General Function Involved in alpha2-adrenergic receptor activity
Specific Function Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 26
Locus Not Available
SNPs ADRA2A
Gene Sequence Not Available
Protein Properties
Number of Residues 452
Molecular Weight 49252.0
Theoretical pI 10.27
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 49-74
  • 86-111
  • 122-144
  • 165-188
  • 208-232
  • 393-417
  • 428-448
Protein Sequence
>Alpha-2A adrenergic receptor
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSG
QPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATA
AELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSS
EHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAK
ASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCN
SSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
GenBank ID Protein AAC24958.1
UniProtKB/Swiss-Prot ID Q28838
UniProtKB/Swiss-Prot Entry Name ADA2A_BOVIN
PDB IDs
GenBank Gene ID U79030
GeneCard ID ADRA2A
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available