Showing Protein P-selectin (BMDBP01890)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01890 |
| Secondary Accession Numbers | None |
| Name | P-selectin |
| Synonyms | Not Available |
| Gene Name | SELP |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Not Available |
| Specific Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes (PubMed:7683458). Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 16 |
| Locus | Not Available |
| SNPs | SELP |
| Gene Sequence |
>1941 bp ATGGCCAGCTGCCCAAAAGCCATCTGGAACTGGAGATTTCAGAGAGCGGTCTTCAGAACT GTCCAACTCCTTTGCTTCAGTGTCCTGATCTTCGAGGTAATAAACCAGAAAGAAGTATCA GCATGGACCTACCACTACAGCAATAAAACATATTCATGGAATTATTCCCGGGCATTCTGT CAGAAGTACTACACGGATTTAGTGGCCATCCAGAATAAAAACGAGATTGCTTATCTCAAC GAGACCATACCTTACTACAACTCTTACTACTGGATTGGTATTCGAAAGATCAACAATAAA TGGACCTGGGTGGGAACCAAAAAGACTCTCACTGAGGAGGCTGAGAACTGGGCTGACAAT GAGCCTAACAACAAGAGGAACAACCAGGACTGTGTGGAGATCTACATCAAGAGTCTGTCA GCCCCTGGCAAGTGGAATGATGAGCCCTGCTGGAAAAGAAAGCGAGCACTCTGCTATAGA GCCTCCTGCCAGGACATGTCCTGCAGCAAGCAAGGAGAGTGCATTGAGACCATTGGGAAC TACACCTGCTCCTGTTACCCTGGATTCTATGGACCGGAGTGTGAATATGTCAGAGAGTGC GGCGAGTTTGATCTTCCTCAACATGTGCACATGAACTGCAGCCACCCTCTTGGAAACTTC TCTTTCAACTCACACTGCAGCTTCCACTGCGCTGAAGGCTATGCGCTGAACGGACCCAGT GAGCTGGAGTGTTTGGCTTCTGGAATCTGGACGAATTCACCCCCACAGTGTGTAGCTGTC CAGTGCCCGGCTCTGAAGTCTCCGGAGCAAGGAAGCATGAGCTGTGTCCAGTCCGCGGAA GCATTCCAGCACCAGTCCAGCTGCAGCTTCAGCTGCGAAGAGGGATTCGCATTAGTTGGG CCAGAGGTAGTGCACTGCACAGCCTTGGGGGTGTGGACAGCCCCAACTCCGGTGTGTAAA GCATTGCAGTGCCAGGATCTTCCGACCTCAACTAAGGCCCGGGTGAACTGCTCGCATCCC TTTGGCGACTTTAGGTACCAGTCGACCTGTAGCTTCACCTGCGATGAAGGTTCATTCCTG GTGGGAGCAAGTGTGCTGCAATGCCTGGATACGGGGAACTGGGATGCTCCTTTTCCAGAA TGCCAAGCTGTTACCTGCGCAGCTCTGCCAAACCCTCAGAATGGAGAAAAGACTTGTGTC CAACCTCTTGGAGGTTCCAGTTATGAGTCCACATGCTGGTTCACATGTCATGAGGGATTC TCTTTATCCGGACCAGAAAGACTGGACTGTACTCCATCTGGACACTGGACGGGCTCCCCA CCAACGTGTGAAGAAGTGGACACAGTATCAGCTCCTGCTCCAGGGGTGCAATGCCCAACC CTCATCGCTCCGAAGCAGGGAACAATGTCCTGTCAGCACCATGTGAGGAACTTTGGTTTG AATACCACTTGCCACTTTGGATGCAAAGCTGGATTCACACTCCTGGGAGATAGTGCTCTC CAGTGCAGACCTTCCAGACAATGGACGGCAGCAGCTCCCACGTGCAGAGCTGTCAAATGC GCCAAGCTACCTGTTACTGAGCCAATAGTGATGAACTGCTCCAACCCTTGGGGAAATTTC AGCTATGGATCAACCTGCAGCTTCCATTGCCCAGAGGGTCAATTACTTAATGGCTCAGAA AGAACAGTATGCCAAGAGAATGGTCAGTGGTCAACGACCATGCCAACCTGTCAAGCAGGG CCACTGACTATCCAGGAAACCCTGACTTATGTTGGTGGAGCAGCAGCTGGTACAACAGGC TTAGTGACGGGTTCAATTCTCCTGGCTCTGCTAAGAAGGCGTTGCAGACAAAAAGATGAT GGAAAAAGCCCCTTGAACCCTCAAAGCCACCTAGGAACATACGGAGTTTTTACAAATGCT GCGTTTGACCCAAGCCCTTAA |
| Protein Properties | |
| Number of Residues | 646 |
| Molecular Weight | 71229.0 |
| Theoretical pI | 6.56 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>P-selectin MASCPKAIWNWRFQRAVFRTVQLLCFSVLIFEVINQKEVSAWTYHYSNKTYSWNYSRAFC QKYYTDLVAIQNKNEIAYLNETIPYYNSYYWIGIRKINNKWTWVGTKKTLTEEAENWADN EPNNKRNNQDCVEIYIKSLSAPGKWNDEPCWKRKRALCYRASCQDMSCSKQGECIETIGN YTCSCYPGFYGPECEYVRECGEFDLPQHVHMNCSHPLGNFSFNSHCSFHCAEGYALNGPS ELECLASGIWTNSPPQCVAVQCPALKSPEQGSMSCVQSAEAFQHQSSCSFSCEEGFALVG PEVVHCTALGVWTAPTPVCKALQCQDLPTSTKARVNCSHPFGDFRYQSTCSFTCDEGSFL VGASVLQCLDTGNWDAPFPECQAVTCAALPNPQNGEKTCVQPLGGSSYESTCWFTCHEGF SLSGPERLDCTPSGHWTGSPPTCEEVDTVSAPAPGVQCPTLIAPKQGTMSCQHHVRNFGL NTTCHFGCKAGFTLLGDSALQCRPSRQWTAAAPTCRAVKCAKLPVTEPIVMNCSNPWGNF SYGSTCSFHCPEGQLLNGSERTVCQENGQWSTTMPTCQAGPLTIQETLTYVGGAAAGTTG LVTGSILLALLRRRCRQKDDGKSPLNPQSHLGTYGVFTNAAFDPSP |
| External Links | |
| GenBank ID Protein | AAA30743.1 |
| UniProtKB/Swiss-Prot ID | P42201 |
| UniProtKB/Swiss-Prot Entry Name | LYAM3_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | L12041 |
| GeneCard ID | SELP |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |