| Identification |
|---|
| BMDB Protein ID
| BMDBP01926 |
| Secondary Accession Numbers
| None |
| Name
| Protein SCO1 homolog, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| SCO1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in copper ion binding |
| Specific Function
| Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| SCO1 |
| Gene Sequence
|
>918 bp
ATGGCAGGGCTGTTGCTCGCGCCCGGCCGGATAATGCGGCTTCCGGGCAGCCAACTTTGG
CGTCTCTTTCCTCGCGGATTCGGGGTTTGGGGCCCAGGGAAGGAGACCGCTAGCGTCTTG
CTAGGGCGGCTCTGCGCGAGGCCAGAGGAGGCATGGCGGGCCTCGGGGCTCGCTGCCTGC
TGCCTGGGGAGCCGCCCCCTCAGCACTGCAATGCCGCCCCCGCCCGGGTCGTCAGGACCG
GAGTGGAAGGGCAGCGGAGACCCCATGCGCCCCTCGAAGCCCGGGCCTGTTTCCTGGAAG
TCTTTAGCCGTCACGTTTGCTATTGGAGGAGCTTTATTGGCTGGAATGAAGTACTTCAAG
AAAGAAAAGACGGAGAAACTGGAGAAGGAACGGCATCGGAGCATTGGAAAGCCTTTACTT
GGGGGCCCATTTTCCCTCACAACTCATACTGGCGAGCCCAAAACTGATAAGGACTACCTG
GGTCAATGGGTATTGATTTATTTTGGTTTTACTCATTGTCCAGATATCTGTCCAGAAGAA
CTAGAAAAAATGATTCAAGTCGTGGATGAAATAGACAGTATTCCAACTCTGCCAAATTTA
ACTCCACTTTTCATCACTATTGACCCAGAGAGGGACACAAAAGAAGCCATCGCCAATTAT
GTAAAAGAATTTTCTCCCAAACTGATTGGCTTGACTGGCACAAAAGAAGAGATCGATCAA
GTGGCCAGAGCATTCAGAGTATATTACAGCCCTGGCCCCAAGGACGAAGATGAGGACTAC
ATAGTTGATCATACAATCATAATGTACTTGATTGGACCAGATGGTGAATTTCTAGATTAT
TTTGGCCAGAACAAGAAGAATGCAGAAATAGCTGGTTCAATTGCTGCACACATGAGGACC
CACAGGAAAAAGAGCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 305 |
| Molecular Weight
| 33658.0 |
| Theoretical pI
| 8.2 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein SCO1 homolog, mitochondrial
MAGLLLAPGRIMRLPGSQLWRLFPRGFGVWGPGKETASVLLGRLCARPEEAWRASGLAAC
CLGSRPLSTAMPPPPGSSGPEWKGSGDPMRPSKPGPVSWKSLAVTFAIGGALLAGMKYFK
KEKTEKLEKERHRSIGKPLLGGPFSLTTHTGEPKTDKDYLGQWVLIYFGFTHCPDICPEE
LEKMIQVVDEIDSIPTLPNLTPLFITIDPERDTKEAIANYVKEFSPKLIGLTGTKEEIDQ
VARAFRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKKNAEIAGSIAAHMRT
HRKKS
|
| External Links |
|---|
| GenBank ID Protein
| AAI26614.1 |
| UniProtKB/Swiss-Prot ID
| A1A4J8 |
| UniProtKB/Swiss-Prot Entry Name
| SCO1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC126613 |
| GeneCard ID
| SCO1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
