| Identification |
|---|
| BMDB Protein ID
| BMDBP01929 |
| Secondary Accession Numbers
| None |
| Name
| Alpha-fetoprotein |
| Synonyms
|
Not Available
|
| Gene Name
| AFP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in copper ion binding |
| Specific Function
| Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| AFP |
| Gene Sequence
|
>1833 bp
ATGAAGTGGGTGGTATCATTCTTTTTACTTTTTCTACTAAATTTTAGCGATTCCAGAACA
ATGCATAAAAATGCATATGGAATAGATTCCATATTGGATTCTTCCCCATGTTCTTCAGGG
ACAAATTTAGTTGGCCTAGCTACCATATTTTTTGCCCAGTCTGTTCAAGGAGCCACTTAC
GAGGAAGTAAGTCAAATGGTGAAAGATGTATTGACTATAATAGAGAAACCCACTGGCAGT
AAGCAACCTGCTGGGTGTTTAGAGAACCAGGTATCTGCCTTTCTGGAAGAAATTTGCCGT
GAAAAGGAAATTCCTGAAAAGTATGGGCTTTCAGACTGCTGCAGCCGAACTGGAGAGGAA
AGACATGACTGTTTCTTGGCACACAAAAAGGCTGCTCCAGCTTCCATTCCACCCTTTCCA
GTTCTGGAACCTGTCACAAGTTGTAAATCGTACAAGGAAAATAGAGAGCTGTTCATAAAC
AGATACATCTATGAAATAGCAAGAAGGCACCCTGTCCTGTATGCACCAACAATTCTTTCT
GTGGCTAATCAATACAATAAAATTATTCCACATTGCTGCAAAGCTGAAAATGCCACTGAA
TGCTTCGAAACAAAGGTAACATCAATTACAAAAGAATTAAGAGAAAGCAGTTTGTTAAAT
CAGCATATATGTGCAGTAATGGGAAAATTTGGACCCCGGACCTTCCGAGCCATAACTGTT
ACTAAAGTGAGTCAAAAGTTTCCCAAAGCTAATTTTACTGAAATTCAGAAACTGGTCATG
GATGTGGCCCACATACATGAGGAATGCTGCAAAGGAAACGTGCTGGAGTGTCTGCAGGAT
GGGGAAAGAGTTATGTCCTACATATGTTCCCAACAAGATATTCTGTCAAGACAAATAGCA
GAGTGCTGCAAGTTGCCCACCACACTTGAACTTGGTCATTGCATAATTCATGCAGAAAAT
GATGACAAACCTGAAGGCTTATCTCCAAATGTAAATAGGTTTTTAGGAGACAGAGATTTC
AACCAACTTTCTTCAAGGGATAAAGATCTCTCCATGGCAAGATTTACATATGAATATTCA
AGAAGACACACTAAGCTTGCTGTTCCAATAATTCTAAGGGTTGCTAAAGGATATCAGGAA
TTACTGGAGAAGTGTTCCCAGTCTGAAAACCCTTCTGAATGCCAGGATAAAGGGGAAGAA
GAACTGGAGAAATATATCCAGGAGAGCCAAGCCCTGGCAAAGCGAAGCTGTGGTCTCTTT
CAGAAATTAGGAGAATATTACTTACAAAATGCGTTTCTTGTTGCTTACACAAAGAAGGCT
CCTCAGCTGACCTCGCCTGAGCTGATGGCCTTGACCAGGAAAATGGCGAACGCAGGAGCC
ATTTGTTGCCATCTCAGTGAGGACAAACAGCTGGCCTGTGGCGAGGGAGTGGCTGACCTT
ATTATAGGACACTTATGCATCAGACATGAAGAGAACCCCATAAACCCTGGTGTTGACCAG
TGCTGCACCTCTTCATACTCCAACAGGAGGCCATGCTTCAGCAGCTTGGTGGTGGATGAG
ACATACGTGCCTCCACCATTCTCCGATGACAAGTTCATCTTCCATAAGGATCTATGCCAA
GTTCAGGGTGTACCACTGCAGACAATGAAGCAACAGTTTCTCATTAACCTTGTGAAGCAG
AAGCCACAAATAACAGAGGAACAATTGGAGACGGTCGTTGCAGATTTCTCTGGCCTCCTG
GAAAAGTGTTGCCAAAGCCAAGAGCAGGAAGTCTGCTTTACAGAAGAGGGTCCAGCACTG
ATTTCAAAAACTCGTGCTGCTTTGGGAGTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 610 |
| Molecular Weight
| 68588.0 |
| Theoretical pI
| 6.24 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 269-290
- 296-316
- 328-348
- 476-496
|
| Protein Sequence
|
>Alpha-fetoprotein
MKWVVSFFLLFLLNFSDSRTMHKNAYGIDSILDSSPCSSGTNLVGLATIFFAQSVQGATY
EEVSQMVKDVLTIIEKPTGSKQPAGCLENQVSAFLEEICREKEIPEKYGLSDCCSRTGEE
RHDCFLAHKKAAPASIPPFPVLEPVTSCKSYKENRELFINRYIYEIARRHPVLYAPTILS
VANQYNKIIPHCCKAENATECFETKVTSITKELRESSLLNQHICAVMGKFGPRTFRAITV
TKVSQKFPKANFTEIQKLVMDVAHIHEECCKGNVLECLQDGERVMSYICSQQDILSRQIA
ECCKLPTTLELGHCIIHAENDDKPEGLSPNVNRFLGDRDFNQLSSRDKDLSMARFTYEYS
RRHTKLAVPIILRVAKGYQELLEKCSQSENPSECQDKGEEELEKYIQESQALAKRSCGLF
QKLGEYYLQNAFLVAYTKKAPQLTSPELMALTRKMANAGAICCHLSEDKQLACGEGVADL
IIGHLCIRHEENPINPGVDQCCTSSYSNRRPCFSSLVVDETYVPPPFSDDKFIFHKDLCQ
VQGVPLQTMKQQFLINLVKQKPQITEEQLETVVADFSGLLEKCCQSQEQEVCFTEEGPAL
ISKTRAALGV
|
| External Links |
|---|
| GenBank ID Protein
| AAI03124.1 |
| UniProtKB/Swiss-Prot ID
| Q3SZ57 |
| UniProtKB/Swiss-Prot Entry Name
| FETA_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC103123 |
| GeneCard ID
| AFP |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
