| Identification |
|---|
| BMDB Protein ID
| BMDBP01936 |
| Secondary Accession Numbers
| None |
| Name
| 5-demethoxyubiquinone hydroxylase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| COQ7 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner. |
| Pathways
|
- Cofactor biosynthesis
- Ubiquinone Biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| COQ7 |
| Gene Sequence
|
>654 bp
ATGAGTTGTGCCCGGGCGTTGGCGGCTTGCTGCCTGTGGCGGCTGCGCACAGGCGCCCTG
CAGCCCCTCTCAGCCTATGGAAGAAGAATCAGTGTCAGATTTTGCAGTTCGGGAATGACC
TTAGACAATATCAATAGGGAAGCTGTGGATCGAATAATCCGGGTGGATCATGCAGGTGAA
TATGGAGCGAACCGCATCTATGCAGGGCAGATGGCCGTCCTGGGTCGGACAAGCATCGGG
CCGGTCATTCAGAAAATGTGGGACCAAGAAAAGGACCACTTGAAAAAGTTCAATGAGCTG
ATGGTTGCATTCAGGGTGCGGCCTACCGTCCTCATGCCCTTTTGGAACGTGGTGGGGTTT
GCACTGGGCGCCGGAACTGCCCTGCTTGGGAAGGAGGGCGCCATGGCCTGCACAGTGGCC
GTGGAAGAGTCCATCGCACACCACTACAACAACCAGATCAGGACGCTGATGGAGAAGGAG
CCTGAAAAATACGAGGAGCTTCTGCAGGTGATCAAGAAATTTCGGGATGAAGAGCTTGAG
CACCATGACATAGGCCTCGAACATGACGCAGAACTGGCTCCAGCATATGTCGTTCTGAAG
AGCGTTATCCAGGCAGGATGCAAAGTGGCGATATATTTATCAGAAAGACTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 217 |
| Molecular Weight
| 24361.0 |
| Theoretical pI
| 7.85 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ubiquinone biosynthesis protein COQ7 homolog
MSCARALAACCLWRLRTGALQPLSAYGRRISVRFCSSGMTLDNINREAVDRIIRVDHAGE
YGANRIYAGQMAVLGRTSIGPVIQKMWDQEKDHLKKFNELMVAFRVRPTVLMPFWNVVGF
ALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEKEPEKYEELLQVIKKFRDEELE
HHDIGLEHDAELAPAYVVLKSVIQAGCKVAIYLSERL
|
| External Links |
|---|
| GenBank ID Protein
| AAI09579.1 |
| UniProtKB/Swiss-Prot ID
| Q2TBW2 |
| UniProtKB/Swiss-Prot Entry Name
| COQ7_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109578 |
| GeneCard ID
| COQ7 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
