| Identification |
|---|
| BMDB Protein ID
| BMDBP01972 |
| Secondary Accession Numbers
| None |
| Name
| V-type proton ATPase subunit a |
| Synonyms
|
Not Available
|
| Gene Name
| TCIRG1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 29 |
| Locus
| Not Available |
| SNPs
| TCIRG1 |
| Gene Sequence
|
>2493 bp
ATGGGCTCCATGTTCCGGAGCGAGGAGGTGGCACTGGTCCAGCTCTTCCTGCCCACAGCT
GCCGCCTACACCTGCGTGAGCCAGCTCGGGGAGCTGGGCCTGGTGGAGTTCAGGGATCTC
AACGCCTCGGTGAGTGCCTTCCAGAGACGCTTCGTGGTGGACGTTCGGCGCTGTGAAGAG
TTGGAGAAGACCTTCACCTTCCTGCAGGAGGAGGTGCGGCGGGCTGGGCTGATGCTGCCT
CTGCCCGAGGCGGGGCTGCCGGCGCCCCCGCCCCGCGACCTTCTGCGCATCCAGGAGGAG
ACTGACCGCCTGGCTCAGGAGCTCCGGGACGTGCGGGGCAACCAGCAGGCCCTGCGGGCC
CAGTGGCACCAGCTGCAGCTCCACTCTGCCGTGCTGGGCCAGGGCCACAGTCCCCCGTCG
GTGGCCACTCACACCGATGGGCCCTCGGAAAGGACCCCCCTGCTCCAGGCCCCCGGAGGG
CCGCACCAGGACCTGAGGGTCAACTTCGTGGCCGGTGCGGTGGAACCCCACAAGGCCGCG
GCCCTGGAGCGCCTGCTCTGGAGGGCCTGCCGCGGCTTCCTCATCGCCAGCTTCCGGGAG
ACGGAGCAGCAGCTGGAGGACCCAGTGACGGGTGAGCCTGCCACGTGGATGACCTTCCTC
ATCTCCTACTGGGGCGGGCAGATAGGGCAGAAGATCCGCAAGATCACTGACTGCTTCCAC
TGCCATGTCTTCCCGTTTGCGGAGGAGGAGGCAGCCCGGCATGCAGCCCTGCAGCAGCTG
CAACAGCAGAGCCAGGAGCTGCAGGAGGTCCTGGGGGAGACGGAGCGCTTCCTGAGCCAG
GTGCTGGGCCGCGTGCAGAGGCTGCTGCCGCCCTGGCAAGTGCAGATCCGCAAGATGAAG
GCCGTGTACCTGGCCCTCAACCAGTGCAGCGTGAGCTCCACGCACAAGTGCCTCATCGCC
GAGGCCTGGTGTGCCACACGTGACCTGCCCACCCTGCAGCAGGCCCTGCAGGACAGCTCG
AGCGAGGCAGGTGTGAGCGCCGTGGTTCACTGCATCCCCTGCCGGGACATGCCCCCCACG
CTCATCCGTACCAACCGCTTCACGGCCAGCTTCCAGGGCATCGTGGACGCCTATGGTGTG
GGCCGCTACCAGGAGGTCAACCCCGCACCCTACACCATCATCACCTTCCCCTTCCTCTTT
GCTGTCATGTTCGGTGACGTGGGCCACGGGCTGCTCATGTTCCTCTTCGCCCTGGCCATG
GTGCTGGCCGAGAACCAGCCGGCTGTGAAGTCAGCGCAGAACGAGATCTGGAGGACCTTC
TTCGGGGGCCGCTACCTGCTGCTGCTCATGGGCCTGTTCTCCGTCTACACTGGCTTCATT
TACAATGAGTGCTTCAGCCGTGCCACGGCCATCTTCCCCTCGGGCTGGAGCGTGGCGGCC
ATGGCCAACCAGTCCGGCTGGAGCGATGCCTTCCTGGCCCAGCACCAGCTGCTTGCCCTG
GACCCCAACGTCACTGGCGTCTTCCTGGGACCCTACCCCTTTGGCATTGACCCTGTCTGG
AGCCTGGCCGTCAACCACCTGAGCTTCCTCAACTCCTTCAAGATGAAGATGTCCATCATC
CTGGGGGTCACCCACATGACCTTTGGGGTGGTCCTGGGAGTCTTCAACCACGTGCACTTC
GGCCAGTGGCACCGGCTGCTGCTGGAGACCCTCCCCGAGCTGGTCTTCCTGCTGGGGCTG
TTCGGCTACCTGGTCTTCCTGGTCGTCTACAAGTGGCTGAGCTTCACGGCCGCCAGCGCT
GCCACAGCCCCCAGCATCCTGATCCACTTCATCAACATGTTCCTCTTCTCGCGCAGCCGC
ACCAACAAGCCGCTCTTCCAGGGGCAGGAGGTGGTGCAGTCCACCCTGGTGGTCCTGGCC
CTGGCCACGGTGCCTGTGCTGCTGCTGGGCACTCCCCTGTTCCTGCGCCGGAGGCACCAG
CGTCGCCAGTCTTCCCGGAGGCGGCAACCGCTGGATGAGGACAAGGCCGGGCTCCTGGGC
CAGCCCGACGTGTCTGTGGCCAGTCAGAACTGTGATGAGGAGAAGGCCGGATGCCTCGGG
GACCAAGAGGAGGAAGAGTTTGTCCTGTCCGAGGTGTTCATGCACCAGGCCATCCACACC
ATCGAGTTCTGCCTCGGCTGCATCTCCAACACGGCCTCCTACTTGCGCCTCTGGGCCCTA
AGCCTGGCCCACGCCCAACTGTCGGAGGTCCTGTGGGCCATGGTGATGCGAGTTGGCTTG
GGCCTGGGTGGCAAGATGGGCGTGGAGGCCCTGGTGCTGGTCCCCGTCTTTGCCGCCTTC
GCCGTGATGACCGTGGCCATCCTGCTGGTGATGGAGGGGCTCTCGGCCTTCCTGCACGCG
CTGCGGCTGCACTGGGTGGAGTTCCAGAACAAGTTCTACTCGGGCTCCGGCTACAAGCTG
AGCCCCTTCACCTTTGCCGTGGAGGATGAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 830 |
| Molecular Weight
| 92645.0 |
| Theoretical pI
| 6.74 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 398-423
- 444-461
- 507-527
- 539-558
- 570-590
- 597-616
- 636-655
- 737-758
- 770-791
|
| Protein Sequence
|
>T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
MGSMFRSEEVALVQLFLPTAAAYTCVSQLGELGLVEFRDLNASVSAFQRRFVVDVRRCEE
LEKTFTFLQEEVRRAGLMLPLPEAGLPAPPPRDLLRIQEETDRLAQELRDVRGNQQALRA
QWHQLQLHSAVLGQGHSPPSVATHTDGPSERTPLLQAPGGPHQDLRVNFVAGAVEPHKAA
ALERLLWRACRGFLIASFRETEQQLEDPVTGEPATWMTFLISYWGGQIGQKIRKITDCFH
CHVFPFAEEEAARHAALQQLQQQSQELQEVLGETERFLSQVLGRVQRLLPPWQVQIRKMK
AVYLALNQCSVSSTHKCLIAEAWCATRDLPTLQQALQDSSSEAGVSAVVHCIPCRDMPPT
LIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAM
VLAENQPAVKSAQNEIWRTFFGGRYLLLLMGLFSVYTGFIYNECFSRATAIFPSGWSVAA
MANQSGWSDAFLAQHQLLALDPNVTGVFLGPYPFGIDPVWSLAVNHLSFLNSFKMKMSII
LGVTHMTFGVVLGVFNHVHFGQWHRLLLETLPELVFLLGLFGYLVFLVVYKWLSFTAASA
ATAPSILIHFINMFLFSRSRTNKPLFQGQEVVQSTLVVLALATVPVLLLGTPLFLRRRHQ
RRQSSRRRQPLDEDKAGLLGQPDVSVASQNCDEEKAGCLGDQEEEEFVLSEVFMHQAIHT
IEFCLGCISNTASYLRLWALSLAHAQLSEVLWAMVMRVGLGLGGKMGVEALVLVPVFAAF
AVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGSGYKLSPFTFAVEDE
|
| External Links |
|---|
| GenBank ID Protein
| AAI14744.1 |
| UniProtKB/Swiss-Prot ID
| Q1RMS1 |
| UniProtKB/Swiss-Prot Entry Name
| Q1RMS1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC114743 |
| GeneCard ID
| TCIRG1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
