| Identification |
|---|
| BMDB Protein ID
| BMDBP01977 |
| Secondary Accession Numbers
| None |
| Name
| V-type proton ATPase subunit a |
| Synonyms
|
Not Available
|
| Gene Name
| ATP6V0A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| ATP6V0A1 |
| Gene Sequence
|
>2499 bp
ATGGGGGAGCTTTTCCGGAGTGAAGAGATGACACTGGCCCAGCTTTTTCTACAGTCAGAA
GCTGCTTATTGTTGTGTCAGTGAATTAGGTGAACTTGGAAAGGTTCAGTTTCGTGATTTA
AATCCAGATGTGAACGTTTTCCAGAGGAAATTTGTGAATGAAGTTAGAAGATGTGAAGAA
ATGGACCGAAAGCTTCGATTTGTTGAGAAAGAGATAAGGAAAGCTAACATCCCAATTATG
GACACTGGTGAAAACCCAGAGGTGCCCTTCCCCCGGGACATGATTGACTTAGAGGCTAAT
TTTGAGAAGATTGAAAATGAACTGAAGGAAATCAACACAAACCAGGAAGCTCTGAAGAGA
AATTTCCTAGAACTAACTGAATTAAAATTTATACTTCGCAAAACTCAACAGTTTTTTGAT
GAGATGGCGGATCCAGACCTGTTGGAAGAGTCCTCGTCCCTCTTGGAGCCAAGCGAGATG
GGAAGAGGCACGCCCTTGAGACTTGGCTTCGTGGCTGGTGTGATTAACCGGGAGCGCATC
CCTACTTTTGAGCGCATGCTTTGGCGGGTGTGCCGGGGGAATGTGTTCCTGCGGCAGGCT
GAAATCGAGAACCCCCTGGAGGATCCTGTGACTGGAGACTACGTGCACAAGTCTGTGTTC
ATCATTTTCTTCCAAGGCGATCAGCTGAAAAACAGAGTCAAGAAAATCTGTGAAGGGTTC
CGGGCTTCACTCTATCCCTGTCCTGAGACGCCGCAGGAGAGAAAGGAGATGGCTTCTGGA
GTTAATACCAGGATTGATGATCTCCAAATGGTTCTGAACCAAACAGAGGATCACCGCCAG
AGGGTTCTTCAGGCTGCTGCCAAGAACATCCGTGTCTGGTTCATCAAGGTGCGGAAGATG
AAGGCCATCTACCATACTTTGAACCTGTGCAACATAGATGTGACCCAGAAGTGCCTAATT
GCGGAGGTCTGGTGCCCTGTCACTGACCTTGACTCCATCCAGTTTGCGCTCAGAAGGGGC
ACGGAGCACAGTGGTTCCACCGTGCCCTCCATTCTGAACAGGATGCAGACAAACCAGACT
CCCCCCACCTATAACAAGACCAACAAGTTCACGTATGGCTTTCAGAACATAGTGGATGCT
TATGGAATTGGAACTTACCGAGAGATAAATCCAGCTCCATACACCATCATCACTTTCCCT
TTCCTGTTTGCTGTGATGTTTGGTGACCTTGGCCATGGCATTTTGATGACTCTTTTTGCT
GTATGGATGGTGTTAAGAGAGAGCCGGATCCTCTCCCAGAAGAATGAGAATGAGATGTTC
AGCACTATATTCAGCGGCAGGTACATCATTCTGTTGATGGGCGTGTTCTCCATCTACACT
GGCCTCATCTATAACGACTGCTTTTCCAAGTCTCTTAATATCTTTGGGTCATCCTGGAGC
GTACGGCCGATGTTCGATATATACAACTGGACGGAAGAGACACTTCGGGGGAACCCTGTC
CTCCAGCTGAACCCAGCCGTCACTGGAGTTTTTGGTGGACCATATCCTTTTGGCATCGAT
CCAATTTGGAACATTGCTACCAATAAACTGACCTTCCTCAACTCCTTTAAGATGAAGATG
TCTGTTATCCTTGGTATCATCCACATGTTGTTTGGAGTCAGCCTGAGCCTTTTCAACCAC
ACCTACTTCAAGAAGCCCCTGAATATCTACTTTGGATTTATTTCAGAAATAATCTTCATG
ACCTCTTTGTTTGGTTACTTGGTTATCCTTATTTTTTACAAGTGGACGGCCTATAATGCT
AAGACATCGGAGAAAGCACCAAGCCTTCTGATCCATTTCATAAATATGTTCCTCTTTTCC
TATGGGGACTCTGGTAATTCAATGCTGTATTCTGGACAGAAAGGAATTCAGTGTTTCCTG
GTAGTGGTTGCACTGCTGTGTGTCCCTTGGATGCTACTGTTTAAACCACTGGTCCTTCGC
CGTCAGTATTTGAGGAGGAAGCATTTGGGAACTCTCAACTTTGGTGGGATCAGGGTGGGC
AACGGACCGACAGAGGAGGATGCTGAGATTATTCAGCATGACCAGCTCTCCACCCATTCA
GAGGACGCAGAGGAGTTTGATTTTGGGGACACCATGGTGCACCAGGCCATCCACACCATC
GAGTACTGCCTGGGCTGCATCTCCAACACCGCCTCCTACCTGCGGCTCTGGGCCCTCAGC
CTCGCTCATGCACAGTTGTCCGAGGTGCTTTGGACCATGGTGATCCACATCGGCCTGAAG
GTGAAGAGCCTGGCCGGGGGCTTGGCGCTGTTCTTCATCTTTGCCGCCTTCGCCACCCTG
ACTGTGGCCATCCTCCTGATCATGGAGGGCCTCTCAGCCTTTCTCCATGCGCTGCGGTTA
CACTGGGTGGAGTTCCAGAACAAGTTCTACAGCGGGACTGGCTTCAAGTTCCTGCCTTTC
TCCTTTGAGCACATCCGGGAAGGGAAGTTTGATGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 832 |
| Molecular Weight
| 95649.0 |
| Theoretical pI
| 6.89 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 401-425
- 445-464
- 542-563
- 569-593
- 634-658
- 765-788
|
| Protein Sequence
|
>ATP6V0A1 protein
MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
NFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPSEMGRGTPLRLGFVAGVINRERI
PTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGF
RASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKM
KAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQT
PPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDLGHGILMTLFA
VWMVLRESRILSQKNENEMFSTIFSGRYIILLMGVFSIYTGLIYNDCFSKSLNIFGSSWS
VRPMFDIYNWTEETLRGNPVLQLNPAVTGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKM
SVILGIIHMLFGVSLSLFNHTYFKKPLNIYFGFISEIIFMTSLFGYLVILIFYKWTAYNA
KTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLR
RQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTI
EYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLKVKSLAGGLALFFIFAAFATL
TVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDD
|
| External Links |
|---|
| GenBank ID Protein
| AAI53214.1 |
| UniProtKB/Swiss-Prot ID
| A7Z016 |
| UniProtKB/Swiss-Prot Entry Name
| A7Z016_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC153213 |
| GeneCard ID
| ATP6V0A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
