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BMDB Protein ID BMDBP01980
Secondary Accession Numbers None
Name Natriuretic peptides B
Synonyms Not Available
Gene Name NPPB
Protein Type Enzyme
Biological Properties
General Function Involved in hormone activity
Specific Function Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 16
Locus Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 129
Molecular Weight 14113.0
Theoretical pI 8.25
Pfam Domain Function Not Available
  • 1-26
Transmembrane Regions
  • 41-60
  • 80-100
  • 107-131
  • 175-203
  • 223-243
  • 262-286
  • 345-366
  • 387-410
  • 415-438
  • 540-562
  • 572-597
  • 631-648
Protein Sequence
>Natriuretic peptides B
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P13204
UniProtKB/Swiss-Prot Entry Name ANFB_BOVIN
PDB IDs Not Available
GenBank Gene ID DAAA02042958
GeneCard ID NPPB
GenAtlas ID Not Available
HGNC ID Not Available
General References Not Available