| Identification |
|---|
| BMDB Protein ID
| BMDBP01986 |
| Secondary Accession Numbers
| None |
| Name
| Cyclic AMP-responsive element-binding protein 3-like protein 3 |
| Synonyms
|
Not Available
|
| Gene Name
| CREB3L3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein dimerization activity |
| Specific Function
| Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds the cAMP response element (CRE). Activates transcription through box-B element and CRE. Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| CREB3L3 |
| Gene Sequence
|
>1371 bp
ATGGATGGGGACTTAGCTATTGGAAAGATGGCTTCCTCCACCAGTCCCATGGGCCCTATC
GACAGCCTGGAACTCCTGGATCTACTGTTTGACCGGCAGGACGGCGTCCTGAGACACGTA
GAGCTGGGAGAGGACTGGGGCCATGGGGAGGACCAGGTCCTGCCAGGTGCGGACTCTGAT
GACTTCCTCAACTCCATCCTGGGTTCTGGAGATTCAGATTCCCCAACCTGGTCCCCCGCG
GCCAGTGACAGTGGCATCTCAGAAGATCTGCCCTCTGACACCCAGGACACACCTCCACAC
GGTGGGGTGCCTGCCACCCCTGCCGGCTGCCATAGTGTGGAGTCTGGCAAGGGGCCCTGC
CCCTCCTACCATCCTGGCCCCACCTGCCCTGCCAGGCACCTCGGGCCAGTGGCCCCAAGG
CTTGAGACTTCTGTTGCCATAGACCTGGAAATGTGGAGCCCAGGCGTCTATGCTGAGGAG
CAGACCGACCTGGCTGACTCGCCCTCACGCTACAACCTCACAGTCAAGGACCTCCTCCTC
TCCAGCAGCAGCGGGGACCTGCAGCAACATCACCTGGCAGCCCCCCACCTGTTGCGACCT
GGGACTGGGCACTGCCAGGAGCTGGTGCTGACGGAGGATGAGAAGAAGCTACTAGCCAAA
GAAGGCATCACTCTGCCCACTCAGCTGCCCCTTACCAAGTATGAGGAGCGAATGCTGAAA
AAGATCCGCCGGAAAATCCGAAACAAACAGTCAGCTCAAGAAAGCCGGAAAAAGAAGAAG
GAATACATTGATGGCCTGGAGACTCGGATGTCAGCTTGTACCGCCCAGAATCAGGAACTT
CAGAGGAAGGTCTTGCATCTCGAAAAGCAGAACCTGTCTCTCTTGGAACAGCTGAAGAAA
CTCCAGGCCATTGTGGTCCAGTCTACCAGCAAATCGGCACAGACGGGCACTTGCATAGCA
GTCCTGCTCTTCTCCTTCGCCCTCATCGTCCTCCCCTCCATCAGCCCTTTCGCCTCCAAC
AGAGCCGAGAGCCCCGGAGACTTCGCACCTGTGCGAGTTTTCTCCAGAACTCTACACAAC
GACGCGGCATCCCGGGTGGCTCCCGACACTGCACCAGGCTCTGAGGCCCCCGGACCCGGG
CCCAACACTGGTGCACTTCAGGAAAGGTCTCCAGGCAGCCCTCCGGGGGAATGGGAATCC
CAGGACACACGTGCTCTGGACAACTCGACAGAGGATCTGGACAACTCAACTCTGGTCCAG
GGCAACTCTGTGAAGGAACTGGACCAGGCCACCCTACTGGACTGTGCCCCACCTGAGCCA
GCAGTCAGCCCGGGCCACGTGGGGCTGGAGGCAGCAGGGGGGGAGCTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 456 |
| Molecular Weight
| 48689.0 |
| Theoretical pI
| 4.65 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cyclic AMP-responsive element-binding protein 3-like protein 3
MDGDLAIGKMASSTSPMGPIDSLELLDLLFDRQDGVLRHVELGEDWGHGEDQVLPGADSD
DFLNSILGSGDSDSPTWSPAASDSGISEDLPSDTQDTPPHGGVPATPAGCHSVESGKGPC
PSYHPGPTCPARHLGPVAPRLETSVAIDLEMWSPGVYAEEQTDLADSPSRYNLTVKDLLL
SSSSGDLQQHHLAAPHLLRPGTGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYEERMLK
KIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLLEQLKK
LQAIVVQSTSKSAQTGTCIAVLLFSFALIVLPSISPFASNRAESPGDFAPVRVFSRTLHN
DAASRVAPDTAPGSEAPGPGPNTGALQERSPGSPPGEWESQDTRALDNSTEDLDNSTLVQ
GNSVKELDQATLLDCAPPEPAVSPGHVGLEAAGGEL
|
| External Links |
|---|
| GenBank ID Protein
| AAI03321.1 |
| UniProtKB/Swiss-Prot ID
| Q3SYZ3 |
| UniProtKB/Swiss-Prot Entry Name
| CR3L3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC103320 |
| GeneCard ID
| CREB3L3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
