Showing Protein Cyclic AMP-dependent transcription factor ATF-1 (BMDBP01989)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01989 |
| Secondary Accession Numbers | None |
| Name | Cyclic AMP-dependent transcription factor ATF-1 |
| Synonyms | Not Available |
| Gene Name | ATF1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in protein dimerization activity |
| Specific Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity). |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 5 |
| Locus | Not Available |
| SNPs | ATF1 |
| Gene Sequence |
>813 bp ATGGAAGATTCTCACAAGAGTAACACTTCAGAGACAGCACCTCAATCTGGTTCCACAGTT CAGGCAGCTCATATTTCTCATATTGCTCAACAGGTATCATCTTTATCAGAGAGTGAGGAG TCTCAGGACTCATCTGACAGCATAGGCTCCTCACAGAAAACCCACGGGATCCTAGCACGG CGCCCATCTTACAGAAAGATTTTGAAAGACCTATCTTCTGAAGATATACGGGGCAGAAAA GGAGACGGAGAAAACCCTGGAGTCTCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATC TATCAGACCAGCACCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGCTGGCC AGTCCAGGCACAGATGGAGTACAGGGCCTTCAGACATTAACCATGACAAATTCAGGCAGT ACTCAGCAAGGTACAACAATTCTCCAGTACGCACAGACTTCTGATGGACAACAAATACTT GTGCCCAGCAACCAGGTTGTTGTACAAACTGCGTCAGGAGATATGCAGACATATCAGATC CGTACTACACCTTCAGCTACTTCACTACCACAGACTGTGGTGATGACATCTCCCGTGACC CTTACATCTCAGACATCCAAGACAGATGACCCCCAACTGAAAAGAGAAATAAGGTTGATG AAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTG GAAAATCGAGTCGCAGTTCTGGAAAATCAAAACAAAACTCTAATAGAAGAGTTAAAAACT TTGAAGGATCTTTATTCTAATAAAAGTGTTTGA |
| Protein Properties | |
| Number of Residues | 270 |
| Molecular Weight | 29261.0 |
| Theoretical pI | 8.64 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Cyclic AMP-dependent transcription factor ATF-1 MEDSHKSNTSETAPQSGSTVQAAHISHIAQQVSSLSESEESQDSSDSIGSSQKTHGILAR RPSYRKILKDLSSEDIRGRKGDGENPGVSAVTSMSVPTPIYQTSTGQYIAIAPNGALQLA SPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQI RTTPSATSLPQTVVMTSPVTLTSQTSKTDDPQLKREIRLMKNREAARECRRKKKEYVKCL ENRVAVLENQNKTLIEELKTLKDLYSNKSV |
| External Links | |
| GenBank ID Protein | AAI23856.1 |
| UniProtKB/Swiss-Prot ID | Q08DA8 |
| UniProtKB/Swiss-Prot Entry Name | ATF1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC123855 |
| GeneCard ID | ATF1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |