Showing Protein cAMP-responsive element modulator (BMDBP01990)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01990 |
| Secondary Accession Numbers | None |
| Name | cAMP-responsive element modulator |
| Synonyms | Not Available |
| Gene Name | CREM |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in protein dimerization activity |
| Specific Function | Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform 1 and isoform 2 are transcriptional activators. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 13 |
| Locus | Not Available |
| SNPs | CREM |
| Gene Sequence |
>918 bp ATGGTTTCTGTAGCTGGATCCAGCACCGGAAGAGGCTCCCCAGCTGTAACTCTAGTACAG TTACCTTCCGGCCAGACCGTCCATGTCCAGGGAGTAATTCAGACACCACAGCCATCCGTT ATTCAGTCACCACAAATACAAACTGTTCAGGTAGCAACCATTGCAGAAACAGATGAGTCT GCAGAATCAGAAGGTGTAATTGATTCTCATAAACGTAGAGAAATCCTTTCACGAAGACCC TCTTACAGAAAAATACTGAATGAACTTTCCTCTGATGTGCCTGGTGTACCCAAGATTGAA GAAGAAAAATCAGAGGAAGAGGGAACACCACCTAACATCGCTGCTATGGCAGTGCCGACT AGCATATATCAGACTAGCACGGGGCAATACATTGCTATAGCCCAAGGTGGAACAATCCAG ATTTCTAACCCAGGATCTGATGGTGTTCAGGGACTGCAGGCATTAACAATGACAAATTCA GGAGCTCCTCCACCAGGTGCTACAATTGTGCAGTACGCAGCACAGTCAGCAGATGGCACA CAGCAGTTCTTTGTCCCAGGCAGCCAGGTGGTGGTTCAAGGTGAGGAAACTGAACTTGCC CCAAGTCACATGGCTGCTGCCACTGGCGACATGCCGACTTACCAGATCCGAGCTCCGACT ACTGCTTTGCCACAGGGAGTGGTGATGGCTGCCTCCCCTGGAAGCCTGCACAGTCCCCAG CAGCTAGCAGAGGAAGCGACACGCAAACGGGAGCTGAGGCTAATGAAAAACAGGGAAGCT GCTAAAGAATGTCGACGTCGAAAGAAAGAATATGTCAAGTGTCTGGAGAGTCGAGTCGCG GTGCTGGAAGTTCAAAACAAGAAGCTTATAGAGGAACTGGAAACCTTGAAAGACATTTGC TCTCCCAAAACAGATTAG |
| Protein Properties | |
| Number of Residues | 360 |
| Molecular Weight | 38694.0 |
| Theoretical pI | 5.49 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>cAMP-responsive element modulator MSKCGRKKYMKTNLRQMTMETIDSQQDGSLPDSVAESESAHMQTQTGQNSIPTLAQVSVA GSSTGRGSPAVTLVQLPSGQTVHVQGVIQTPQPSVIQSPQIQTVQVATIAETDESAESEG VIDSHKRREILSRRPSYRKILNELSSDVPGVPKIEEEKSEEEGTPPNIAAMAVPTSIYQT STGQYIAIAQGGTIQISNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFV PGSQVVVQDEETELAPSHMAAATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEE ATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTD |
| External Links | |
| GenBank ID Protein | AAI02678.1 |
| UniProtKB/Swiss-Prot ID | Q1LZH5 |
| UniProtKB/Swiss-Prot Entry Name | CREM_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC102677 |
| GeneCard ID | CREM |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |