| Identification |
|---|
| BMDB Protein ID
| BMDBP01990 |
| Secondary Accession Numbers
| None |
| Name
| cAMP-responsive element modulator |
| Synonyms
|
Not Available
|
| Gene Name
| CREM |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein dimerization activity |
| Specific Function
| Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform 1 and isoform 2 are transcriptional activators. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 13 |
| Locus
| Not Available |
| SNPs
| CREM |
| Gene Sequence
|
>918 bp
ATGGTTTCTGTAGCTGGATCCAGCACCGGAAGAGGCTCCCCAGCTGTAACTCTAGTACAG
TTACCTTCCGGCCAGACCGTCCATGTCCAGGGAGTAATTCAGACACCACAGCCATCCGTT
ATTCAGTCACCACAAATACAAACTGTTCAGGTAGCAACCATTGCAGAAACAGATGAGTCT
GCAGAATCAGAAGGTGTAATTGATTCTCATAAACGTAGAGAAATCCTTTCACGAAGACCC
TCTTACAGAAAAATACTGAATGAACTTTCCTCTGATGTGCCTGGTGTACCCAAGATTGAA
GAAGAAAAATCAGAGGAAGAGGGAACACCACCTAACATCGCTGCTATGGCAGTGCCGACT
AGCATATATCAGACTAGCACGGGGCAATACATTGCTATAGCCCAAGGTGGAACAATCCAG
ATTTCTAACCCAGGATCTGATGGTGTTCAGGGACTGCAGGCATTAACAATGACAAATTCA
GGAGCTCCTCCACCAGGTGCTACAATTGTGCAGTACGCAGCACAGTCAGCAGATGGCACA
CAGCAGTTCTTTGTCCCAGGCAGCCAGGTGGTGGTTCAAGGTGAGGAAACTGAACTTGCC
CCAAGTCACATGGCTGCTGCCACTGGCGACATGCCGACTTACCAGATCCGAGCTCCGACT
ACTGCTTTGCCACAGGGAGTGGTGATGGCTGCCTCCCCTGGAAGCCTGCACAGTCCCCAG
CAGCTAGCAGAGGAAGCGACACGCAAACGGGAGCTGAGGCTAATGAAAAACAGGGAAGCT
GCTAAAGAATGTCGACGTCGAAAGAAAGAATATGTCAAGTGTCTGGAGAGTCGAGTCGCG
GTGCTGGAAGTTCAAAACAAGAAGCTTATAGAGGAACTGGAAACCTTGAAAGACATTTGC
TCTCCCAAAACAGATTAG
|
| Protein Properties |
|---|
| Number of Residues
| 360 |
| Molecular Weight
| 38694.0 |
| Theoretical pI
| 5.49 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>cAMP-responsive element modulator
MSKCGRKKYMKTNLRQMTMETIDSQQDGSLPDSVAESESAHMQTQTGQNSIPTLAQVSVA
GSSTGRGSPAVTLVQLPSGQTVHVQGVIQTPQPSVIQSPQIQTVQVATIAETDESAESEG
VIDSHKRREILSRRPSYRKILNELSSDVPGVPKIEEEKSEEEGTPPNIAAMAVPTSIYQT
STGQYIAIAQGGTIQISNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFV
PGSQVVVQDEETELAPSHMAAATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEE
ATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTD
|
| External Links |
|---|
| GenBank ID Protein
| AAI02678.1 |
| UniProtKB/Swiss-Prot ID
| Q1LZH5 |
| UniProtKB/Swiss-Prot Entry Name
| CREM_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102677 |
| GeneCard ID
| CREM |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
