Identification
BMDB Protein ID BMDBP01992
Secondary Accession Numbers None
Name Cyclic AMP-dependent transcription factor ATF-3
Synonyms Not Available
Gene Name ATF3
Protein Type Enzyme
Biological Properties
General Function Involved in protein dimerization activity
Specific Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 16
Locus Not Available
SNPs ATF3
Gene Sequence
>546 bp
ATGATGCTTCAACACCCAGGCCAGGTCTCTGCCTCGGAAGTCAGTGCCTCTGCCTTCGTC
CCCTGCCTGTCCCCTCCTGGGTCACTGGTGTTTGAGGATTTTGCTAACCTGACACCCTTT
GTCAAGGAAGAGCTGAGGTTGGCCATCCAGAGCAAGCACCTCTGCCACCGGATGTCCTCG
GCGCTGGACTCCGTCACCGTCAGCGGCAGGCCCCTCGAGATGTCAGTCACCAAAGCCGAG
GTAGCCCCTGAAGAAGATGAAAGGAAAAAGAGGCGACGGGAAAGAAATAAGATTGCAGCC
GCCAAGTGCCGCAACAAGAAGAAGGAGAAGACAGAGTGCCTGCAGAAAGAGTCGGAGAAG
CTGGAGAGTGTGAATGCTGAGCTGAAGGCGCAGATTGAGGAGCTCAAGAACGAGAAGCAG
CATTTGATATACATGCTCAACCTGCACCGGCCCACGTGTATTGTCCGGGCTCAGAACGGG
CGGACTCCGGAAGATGAGAGGAACCTTTTTATCCAACAGATAAAGGAGGGAACATTGCAG
AGCTAA
Protein Properties
Number of Residues 181
Molecular Weight 20567.0
Theoretical pI 8.76
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 61-78
Protein Sequence
>Cyclic AMP-dependent transcription factor ATF-3
MMLQHPGQVSASEVSASAFVPCLSPPGSLVFEDFANLTPFVKEELRLAIQSKHLCHRMSS
ALDSVTVSGRPLEMSVTKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEK
LESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQ
S
GenBank ID Protein AAI12630.1
UniProtKB/Swiss-Prot ID Q2KII1
UniProtKB/Swiss-Prot Entry Name ATF3_BOVIN
PDB IDs Not Available
GenBank Gene ID BC112629
GeneCard ID ATF3
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available