Identification |
BMDB Protein ID
| BMDBP01992 |
Secondary Accession Numbers
| None |
Name
| Cyclic AMP-dependent transcription factor ATF-3 |
Synonyms
|
Not Available
|
Gene Name
| ATF3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein dimerization activity |
Specific Function
| This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 16 |
Locus
| Not Available |
SNPs
| ATF3 |
Gene Sequence
|
>546 bp
ATGATGCTTCAACACCCAGGCCAGGTCTCTGCCTCGGAAGTCAGTGCCTCTGCCTTCGTC
CCCTGCCTGTCCCCTCCTGGGTCACTGGTGTTTGAGGATTTTGCTAACCTGACACCCTTT
GTCAAGGAAGAGCTGAGGTTGGCCATCCAGAGCAAGCACCTCTGCCACCGGATGTCCTCG
GCGCTGGACTCCGTCACCGTCAGCGGCAGGCCCCTCGAGATGTCAGTCACCAAAGCCGAG
GTAGCCCCTGAAGAAGATGAAAGGAAAAAGAGGCGACGGGAAAGAAATAAGATTGCAGCC
GCCAAGTGCCGCAACAAGAAGAAGGAGAAGACAGAGTGCCTGCAGAAAGAGTCGGAGAAG
CTGGAGAGTGTGAATGCTGAGCTGAAGGCGCAGATTGAGGAGCTCAAGAACGAGAAGCAG
CATTTGATATACATGCTCAACCTGCACCGGCCCACGTGTATTGTCCGGGCTCAGAACGGG
CGGACTCCGGAAGATGAGAGGAACCTTTTTATCCAACAGATAAAGGAGGGAACATTGCAG
AGCTAA
|
Protein Properties |
Number of Residues
| 181 |
Molecular Weight
| 20567.0 |
Theoretical pI
| 8.76 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Cyclic AMP-dependent transcription factor ATF-3
MMLQHPGQVSASEVSASAFVPCLSPPGSLVFEDFANLTPFVKEELRLAIQSKHLCHRMSS
ALDSVTVSGRPLEMSVTKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEK
LESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQ
S
|
External Links |
GenBank ID Protein
| AAI12630.1 |
UniProtKB/Swiss-Prot ID
| Q2KII1 |
UniProtKB/Swiss-Prot Entry Name
| ATF3_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC112629 |
GeneCard ID
| ATF3 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |