| Identification |
|---|
| BMDB Protein ID
| BMDBP01995 |
| Secondary Accession Numbers
| None |
| Name
| Cyclic nucleotide-gated cation channel beta-1 |
| Synonyms
|
Not Available
|
| Gene Name
| CNGB1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cAMP binding |
| Specific Function
| Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| CNGB1 |
| Gene Sequence
|
>4185 bp
ATGCTGGGCTGGGTCCAGAGGGTGCTGCCTCAGCCCCCAGGGACCCCTCAGAAGACCAAG
CAAGAGGAGGAGGGGACAGAACCAGAGCCAGAGTTGGAGCCGAAGCCTGAAACAGCTCCC
GAGGAGACTGAGCTAGAGGAAGTGTCCCTGCCACCAGAGGAGCCCTGCGTGGGGAAGGAA
GTGGCTGCGGTTACTCTGGGTCCTCAGGGAACCCAGGAGACTGCTCTCACTCCGCCCACA
TCCCTCCAGGCTCAGGTCTCTGTGGCTCCCGAAGCTCACAGCAGTCCCAGAGGCTGGGTG
CTGACCTGGCTCAGGAAGGGTGTGGAGAAGGTTGTCCCGCAGCCCGCCCACAGCAGCAGG
CCCTCCCAGAACATTGCTGCAGGCCTGGAGAGTCCAGATCAGCAGGCAGGAGCACAGATC
CTTGGGCAGTGCGGCACTGGGGGCTCAGATGAACCCAGTGAACCCTCCAGGGCCGAAGAC
CCCGGGCCTGGGCCCTGGCTCCTCCGGTGGTTCGAACAGAATCTGGAGAAAATGCTGCCT
CAGCCCCCGAAAATCTCTGAGGGCTGGAGAGATGAGCCTACAGATGCTGCCTTGGGTCCA
GAGCCCCCAGGACCCGCCTTGGAGATCAAGCCCATGCTGCAGGCCCAGGAGAGCCCCTCC
CTGCCAGCTCCTGGCCCCCCGGAGCCTGAGGAGGAACCGATCCCAGAGCCCCAGCCCACT
ATTCAAGCCTCCTCCCTGCCGCCCCCGCAGGACTCTGCCAGGTTGATGGCATGGATCCTG
CACAGGCTGGAGATGGCCCTGCCACAGCCAGTGATCCGTGGGAAGGGTGGGGAGCAGGAG
TCTGATGCCCCAGTGACATGTGACGTGCAGACCATCAGCATCCTCCCTGGAGAGCAAGAG
GAGTCGCATCTCATCCTAGAAGAGGTTGACCCTCACTGGGAGGAGGATGAACACCAGGAG
GGCAGCACCAGCACCAGCCCGCGGACCTCAGAGGCAGCTCCAGCTGATGAAGAGAAGGGC
AAGGTGGTGGAGCAGACGCCCAGGGAGCTGCCTCGGATTCAAGAGGAGAAAGAAGATGAG
GAGGAGGAGAAGGAAGACGGAGAGGAGGAAGAAGAGGAAGGCAGAGAGAAAGAGGAGGAA
GAAGGTGAAGAAAAAGAGGAGGAGGAAGGCAGAGAGAAAGAGGAGGAAGAAGGCGAAAAA
AAAGAGGAAGAAGGCAGAGAGAAAGAGGAGGAAGAAGGTGGAGAGAAAGAAGATGAAGAA
GGCAGAGAGAAAGAGGAGGAAGAAGGCAGAGGGAAAGAGGAAGAAGAAGGTGGAGAGAAA
GAGGAAGAAGAAGGCAGAGGGAAAGAGGAGGTGGAAGGCAGAGAGGAGGAGGAAGACGAA
GAGGAGGAGCAGGATCACAGTGTCCTGCTGGATAGTTATCTGGTGCCACAGAGCGAGGAG
GACCGGAGTGAAGAAAGTGAAACCCAGGACCAGAGTGAAGTGGGCGGAGCCCAGGCCCAG
GGCGAAGTGGGCGGCGCCCAGGCCCTGAGTGAAGAAAGTGAAACCCAGGACCAGAGTGAA
GTAGGCGGAGCCCAGGACCAGAGTGAAGTGGGCGGAGCCCAGGCCCAGGGCGAAGTGGGT
GGAGCCCAGGAGCAGGACGGAGTAGGCGGAGCCCAGGACCAGAGCACCTCACACCAGGAG
CTGCAAGAAGAGGCCTTGGCCGACAGCTCAGGAGTACCTGCCACAGAAGAGCACCCCGAA
CTGCAGGTGGAAGACGCTGATGCTGACAGTCGCCCCCTCATCGCGGAGGAGAACCCACCC
TCTCCCGTGCAGCTGCCCCTGTCTCCTGCCAAATCCGACACCCTTGCAGTCCCAGGATCA
GCCACAGGGAGCCTCAGGAAGAGGCTGCCTTCCCAAGATGATGAGGCTGAAGAGCTCAAG
ATGCTGTCACCGGCTGCATCCCCCGTGGTTGCCTGGTCGGACCCCACCAGCCCACAGGGC
ACTGATGACCAGGACCGTGCAACCTCGACAGCCAGCCAGAACAGTGCCATCATCAATGAC
CGGCTCCAGGAGCTGGTGAAGCTCTTCAAGGAGCGGACGGAGAAGGTGAAGGAGAAGCTC
ATCGACCCTGACGTCACCTCCGATGAGGAGAGCCCCAAGCCCTCCCCAGCCAAAAAAGCC
CCAGAGCCGGCCCCAGAAGTGAAGCCAGCTGAAGCGGGGCAGGTGGAAGAGGAACACTAC
TGTGAGATGCTCTGCTGCAAGTTCAAACGCCGCCCCTGGAAGAAGTACCAGTTTCCCCAG
AGCATCGACCCGCTGACCAACCTGATGTACATCTTGTGGCTGTTCTTCGTGGTGCTGGCC
TGGAACTGGAACTGCTGGCTGATTCCCGTGCGCTGGGCCTTCCCCTATCAGACGCCAGAC
AACATCCACCTCTGGCTGCTGATGGATTACCTGTGTGACCTCATCTACCTCCTGGACATC
ACCGTGTTCCAGATGCGCCTGCAGTTTGTCAGAGGCGGGGACATCATTACGGACAAAAAG
GAGATGCGCAACAATTACGTGAAATCTCAGCGCTTTAAGATGGACATGCTCTGCCTCTTG
CCCTTGGACTTACTCTACTTGAAATTCGGTGTGAATCCCCTCCTGCGCTTGCCCCGCTGT
TTGAAGTATATGGCCTTCTTTGAGTTTAACAACCGCCTGGAATCCATCCTCAGCAAAGCC
TACGTTTACAGGGTTATCAGGACCACAGCCTACCTGCTCTACAGCTTACATCTGAACTCA
TGTCTCTATTACTGGGCATCGGCCTATGAGGGCCTCGGCTCCACTCACTGGGTTTATGAT
GGCGTGGGAAACAGTTACATTCGCTGTTACTACTGGGCTGTGAAGACCCTCATCACCATC
GGCGGCCTGCCCGACCCCAGGACGCTCTTTGAAATTGTCTTCCAGGGTCTAAACTATTTC
ACGGGCGTCTTCGCTTTCTCCGTGATGATCGGACAGATGAGAGACGTAGTGGGGGCCGCC
ACCGCGGGACAGACCTACTACCGCAGCTGCATGGACAGCACCGTGAAGTATATGAACTTC
TACAAGATCCCCAGGTCCGTGCAGAACCGGGTCAAGACCTGGTACGAATACACCTGGCAC
TCCCAAGGCATGCTGGATGAGTCAGAGCTGATGGTGCAGCTTCCGGACAAGATGCGGCTG
GACCTCGCCATTGACGTGAACTATTCCATCGTCAGCAAAGTGGCACTCTTCCAGGGCTGT
GACCGGCAGATGATCTTTGACATGCTGAAGAGGCTGCGCTCTGTAGTCTACCTGCCCAAT
GATTACGTGTGCAAGAAGGGGGAGATAGGCCGGGAAATGTACATCATCCAGGCGGGGCAG
GTGCAGGTCTTGGGTGGCCCGGATGGGAAATCCGTGCTGGTGACGCTGAAGGCTGGATCT
GTGTTCGGAGAAATAAGCTTGCTGGCTGTAGGGGGCGGGAACCGGCGCACAGCTAACGTG
GTGGCCCATGGGTTTACCAACCTCTTCATTCTGGATAAGAAGGACCTGAATGAAATTCTG
GTGCATTATCCCGAGTCTCAGAAGTTGCTCCGCAAGAAGGCCAGGCGAATGCTGAGAAAT
AACAACAAGCCCAAGGAGAAGAGCGTGCTTATTCTCCCTCCGCGGGCAGGCACCCCCAAG
CTCTTCAATGCCGCCCTGGCCGCAGCAGGAAAGATGGGTGCCAAGGGAGGCAGAGGTGGC
AGGCTTGCCCTCCTCAGGGCTCGACTCAAGGAGCTGGCTGCGCTGGAGGCGGCCGCCAGA
CAGCAGCAGTTGCTGGAACAGGCCAAGAGCTCGGAAGACGCCGCCGTGGGAGAGGAGGGA
TCGGCCTCCCCAGAACAGCCTCCGCGTCCAGAGCCGCCGGCCCCAGAGGCCCCCGCACCA
GAACCGACGGCCCCAGAGCCCCTGGCCCCAGAGGCCCCCGCCCCAGAGGCCCCGGCCCCA
AGCTCTCCACCACCTGCCTCCCAGGAGAGGCCGGAGGGAGACAAGGACGCGGCGCGGCCA
GAAGAGCACCCGGTGCGGATCCACGTGACCCTGGGCCCGGATCCCAGCGAACAGATCCTG
TTGGTGGAGGTCCCTGAGAAGCAGGAGGAGAAGGAGAAAAAGGAGGAGGAGACAGAGGAA
AAGGAGGAAGGGGAGGAGGCGAGGAAGGAGAAAGAGGAGGAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 1394 |
| Molecular Weight
| 155065.0 |
| Theoretical pI
| 4.24 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 771-789
- 804-822
- 848-867
- 905-927
- 972-991
- 1076-1096
|
| Protein Sequence
|
>Cyclic nucleotide-gated cation channel beta-1
MLGWVQRVLPQPPGTPQKTKQEEEGTEPEPELEPKPETAPEETELEEVSLPPEEPCVGKE
VAAVTLGPQGTQETALTPPTSLQAQVSVAPEAHSSPRGWVLTWLRKGVEKVVPQPAHSSR
PSQNIAAGLESPDQQAGAQILGQCGTGGSDEPSEPSRAEDPGPGPWLLRWFEQNLEKMLP
QPPKISEGWRDEPTDAALGPEPPGPALEIKPMLQAQESPSLPAPGPPEPEEEPIPEPQPT
IQASSLPPPQDSARLMAWILHRLEMALPQPVIRGKGGEQESDAPVTCDVQTISILPGEQE
ESHLILEEVDPHWEEDEHQEGSTSTSPRTSEAAPADEEKGKVVEQTPRELPRIQEEKEDE
EEEKEDGEEEEEEGREKEEEEGEEKEEEEGREKEEEEGEKKEEEGREKEEEEGGEKEDEE
GREKEEEEGRGKEEEEGGEKEEEEGRGKEEVEGREEEEDEEEEQDHSVLLDSYLVPQSEE
DRSEESETQDQSEVGGAQAQGEVGGAQALSEESETQDQSEVGGAQDQSEVGGAQAQGEVG
GAQEQDGVGGAQDQSTSHQELQEEALADSSGVPATEEHPELQVEDADADSRPLIAEENPP
SPVQLPLSPAKSDTLAVPGSATGSLRKRLPSQDDEAEELKMLSPAASPVVAWSDPTSPQG
TDDQDRATSTASQNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKA
PEPAPEVKPAEAGQVEEEHYCEMLCCKFKRRPWKKYQFPQSIDPLTNLMYILWLFFVVLA
WNWNCWLIPVRWAFPYQTPDNIHLWLLMDYLCDLIYLLDITVFQMRLQFVRGGDIITDKK
EMRNNYVKSQRFKMDMLCLLPLDLLYLKFGVNPLLRLPRCLKYMAFFEFNNRLESILSKA
YVYRVIRTTAYLLYSLHLNSCLYYWASAYEGLGSTHWVYDGVGNSYIRCYYWAVKTLITI
GGLPDPRTLFEIVFQGLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNF
YKIPRSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYSIVSKVALFQGC
DRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKSVLVTLKAGS
VFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRN
NNKPKEKSVLILPPRAGTPKLFNAALAAAGKMGAKGGRGGRLALLRARLKELAALEAAAR
QQQLLEQAKSSEDAAVGEEGSASPEQPPRPEPPAPEAPAPEPTAPEPLAPEAPAPEAPAP
SSPPPASQERPEGDKDAARPEEHPVRIHVTLGPDPSEQILLVEVPEKQEEKEKKEEETEE
KEEGEEARKEKEEE
|
| External Links |
|---|
| GenBank ID Protein
| CAA61769.1 |
| UniProtKB/Swiss-Prot ID
| Q28181 |
| UniProtKB/Swiss-Prot Entry Name
| CNGB1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X89626 |
| GeneCard ID
| CNGB1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
