Showing Protein Solute carrier family 2, facilitated glucose transporter member 4 (BMDBP02025)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02025 |
| Secondary Accession Numbers | None |
| Name | Solute carrier family 2, facilitated glucose transporter member 4 |
| Synonyms | Not Available |
| Gene Name | SLC2A4 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Carbohydrate transport and metabolism |
| Specific Function | Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | Not Available |
| SNPs | SLC2A4 |
| Gene Sequence |
>1530 bp ATGCCGTCGGGCTTCCAACAGATCGGCTCTGAAGATGGGGAGCCCCCTCGGCAGCGAGTC ACTGGGACCTTGGTCCTTGGCGTATTCTCCGCTGTTCTTGGCTCCCTGCAGTTTGGCTAC AACATTGGGGTCATCAATGCCCCCCAGAAGGTGATTGAACAGAGCTACAATGAGACCTGG CTGGGGAGGCAGGGGCCTGAGGGACCCGGCTCCATCCCACCAGGCACACTTACCACACTC TGGGCTCTCTCCGTGGCCATCTTCTCTGTGGGTGGCATGATCTCATCCTTCCTGATTGGC ATCATCTCTCAGTGGCTGGGAAGGAAGAGGGCCATGCTGTTCAGCAACGCCCTGGCAGTG CTGGGGGGCACCCTCATGGGCCTGGCCAAGGCAGCTGCCTCCTATGAGATGCTCATTCTT GGACGGTTCTTCATTGGAGCCTACTCAGGACTGACGTCGGGACTGGTACCCATGTACGTG GGGGAGATTGCCCCTACTCACCTGCGGGGCGCCCTGGGGACACTCAATCAACTAGCCATC GTCACTGGCATCCTAATCGCCCAGGTGCTAGGTTTGGAGTCCATGCTGGGCACAGCCACC TTATGGCCACTCCTCCTGGGCATCACCGTGCTGCCTGCCCTCCTGCAGATGGTCCTGCTG CCCCTCTGCCCGGAAAGCCCCCGCTACCTCTACATCATCCGGAACCTGGAGGGGCCCGCC AGAAAGAGTCTGAAGCGCCTGACGGGGTGGGCCGACGTGTCTGAGGTGTTGGCTGAGCTG AAGGAGGAGAAGCGGAAGCTGGAGCGTGAGCGGTCCCTGTCCTTGCTCCAGCTCCTGGGC AGCCACACCCATCGGCAGCCCCTCGTCATCGCCATTGTGCTGCAGCTGAGCCAGCAGCTC TCAGGCATCAATGCGGTTTTCTATTATTCCACCAGCATCTTTGAGTCAGCGGGGGTAGAG AAACCAGCCTATGCCACCATTGGAGCCGGCGTGGTCAACACAGTCTTCACCTTAGTCTCG GTGTTCTTGGTGGAACGGGCTGGGCACCGGACCCTCCATCTCCTGGGCCTGGCAGGCATG TGTGCCTGCGCCATCTTGATGACTGTGGCTCTGCTTCTGCTGGAGCGGGTTCCAGCCATG AGCTATGTCTCCATTGTGGCCATCTTTGGCTTCGTGGCCTTCTTTGAAATTGGCCCTGGC CCCATCCCCTGTTTCATCGTGGCCGAGCTCTTCAGCCAGGGGCCCCGCCCAGCGGCCATG GCAGTGGCTGGGTTCTCCAACTGGACATGCAACTTCATCATCGGCATGGGTTTCCAGTAT GTGGCGGATGCTATGGGTCCCTACGTCTTTCTTCTATTCGCGGTCCTCCTGCTTGGCTTC TTCATCTTCACCTTCTTAAAAGTGCCTGAAACCCGAGGCAGGACGTTTGACCAGATCTCA GCCGTTTTCCACCGGACACCTTCTCTTCTGGAGCAGGAAGTGAAACCCAGCACAGAACTG GAGTACTTAGGGCCAGATGAGCATGACTGA |
| Protein Properties | |
| Number of Residues | 509 |
| Molecular Weight | 55084.0 |
| Theoretical pI | 7.54 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Solute carrier family 2, facilitated glucose transporter member 4 MPSGFQQIGSEDGEPPRQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW LGRQGPEGPGSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLFNNALAV LGGTLMGLAKAAASYEMLILGRFFIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI VTGILIAQVLGLESMLGTATLWPLLLGITVLPALLQMVLLPLCPESPRYLYIIRNLEGPA RKSLKRLTGWADVSEVLAELKEEKRKLERERPLSLLQLLGSHTHRQPLVIAIVLQLSQQL SGINAVFYYSTSIFESAGVEKPAYATIGAGVVNTVFTLVSVFLVERAGRRTLHLLGLAGM CGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM AVAGFSNWTCNFIIGMGFQYVADAMGPYVFLLFAVLLLGFFIFTFLKVPETRGRTFDQIS AVFHRTPSLLEQEVKPSTELEYLGPDEHD |
| External Links | |
| GenBank ID Protein | BAA21105.1 |
| UniProtKB/Swiss-Prot ID | Q27994 |
| UniProtKB/Swiss-Prot Entry Name | GLUT4_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | D63150 |
| GeneCard ID | SLC2A4 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |