Identification
BMDB Protein ID BMDBP02026
Secondary Accession Numbers None
Name E-selectin
Synonyms Not Available
Gene Name SELE
Protein Type Enzyme
Biological Properties
General Function Involved in protein binding
Specific Function Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 16
Locus Not Available
SNPs SELE
Gene Sequence
>1458 bp
ATGATTGTGTCACAGTATCTCTCTGCTCTCACTTTTGTGCTTCTCCTGTTTAAAGAAAGT
AGAACCTGGTCTTACCATGCATCCACGGAAATGATGACTTTTGAGGAGGCCAGAGATTAT
TGCCAGAAAACTTACACAGCTCTAGTTGCAATTCAAAACCAGGAAGAGATTGAATACCTG
AACTCCACATTCAGCTATTCACCAAGTTACTACTGGATTGGAATCAGAAAGATCAACGGT
ACATGGACCTGGATAGGGACCAATAAGTCCTTGACCAAAGAAGCCACAAACTGGGCTCCA
GGTGAACCAAACAATAAGCAAAGTGATGAGGACTGTGTAGAGATCTATATTAAGAGAGAA
AAAGACTCAGGCAAGTGGAATGATGAGAAATGCACCAAACAGAAACTCGCCTTGTGTTAC
AAAGCTGCCTGTAACCCCACACCCTGCGGCAGCCATGGTGAATGTGTAGAGACCATCAAC
AACTACACTTGTCAGTGCCACCCTGGCTTCAAGGGCCTCAAATGTGAGCAAGTTGTGACC
TGTCCAGCACAGAAACATCCTGAGCATGGACATCTGGTTTGCAACCCTTTGGGGAAATTC
ACCTACAACTCTTCCTGCTCCATCAGCTGTGCAGAGGGCTACCTCCCAAGCAGCACAGAG
GCCACTCGGTGCATGTCCTCTGGAGAATGGAGCACTCCTCTCCCAAAATGCAATGTGGTT
AAGTGTGATGCTTTGTCAAATCTGGACAATGGAGTGGTAAACTGTTCCCCAAACCATGGA
AGCCTCCCATGGAACACCACCTGTACGTTTGAGTGTCAGGAAGGATATAAACTCACTGGA
CCCCAGCACCTACAGTGTACCTCCTCTGGGATTTGGGACAACAAGCAGCCAACATGTAAA
GCTGTAAGCTGTGCAGCCATCAGCCATCCTCAGAACGGCACTGTGAACTGTAGCCACTCC
GTGGTTGGAGACTTTGCCTTCAAGTCATCCTGCCACTTCACCTGTGCAGAGGGCTTCACG
TTGCAGGGGCCAACCCAGGTTGAATGCACTGCCCAGGGACAATGGACACAGCGGGTCCCA
GTTTGTGAAGTGGTACGATGTTCACGTTTGGACGTTTCTGGAAAGCTCAACATGAACTGC
AGTGGGGAGCCCGTGCTTGGCACTGAGTGTACGTTTGCATGTCCTGAAAGATGGACGCTC
AATGGCTCTGTAGTGCTGACCTGCGGTGCTACAGGACACTGGTCTGGGATGCTGCCAACC
TGTGAAGCTCCGACTGTGTCCCAAACTCCCTTGGCAGTTGGACTTTCTACTGCTGGAGTC
TCCCTTGTGACAATACCATCATTTCTCTTCTGGCTTCTGAAACGCCTTCAGAAGAAAGCA
AAAAAATTTTCTCCTGCCAGCAGCTGCTCAAGCCTGAAATCCAATGGATGCTACTCAACA
CCTTCCAAGTTAATTTAA
Protein Properties
Number of Residues 485
Molecular Weight 53200.0
Theoretical pI 7.47
Pfam Domain Function Not Available
Signals
  • 1-22
Transmembrane Regions
  • 431-453
Protein Sequence
>E-selectin
MIVSQYLSALTFVLLLFKESRTWSYHASTEMMTFEEARDYCQKTYTALVAIQNQEEIEYL
NSTFSYSPSYYWIGIRKINGTWTWIGTNKSLTKEATNWAPGEPNNKQSDEDCVEIYIKRE
KDSGKWNDEKCTKQKLALCYKAACNPTPCGSHGECVETINNYTCQCHPGFKGLKCEQVVT
CPAQKHPEHGHLVCNPLGKFTYNSSCSISCAEGYLPSSTEATRCMSSGEWSTPLPKCNVV
KCDALSNLDNGVVNCSPNHGSLPWNTTCTFECQEGYKLTGPQHLQCTSSGIWDNKQPTCK
AVSCAAISHPQNGTVNCSHSVVGDFAFKSSCHFTCAEGFTLQGPTQVECTAQGQWTQRVP
VCEVVRCSRLDVSGKLNMNCSGEPVLGTECTFACPERWTLNGSVVLTCGATGHWSGMLPT
CEAPTVSQTPLAVGLSTAGVSLVTIPSFLFWLLKRLQKKAKKFSPASSCSSLKSNGCYST
PSKLI
GenBank ID Protein AAA02991.1
UniProtKB/Swiss-Prot ID P98107
UniProtKB/Swiss-Prot Entry Name LYAM2_BOVIN
PDB IDs Not Available
GenBank Gene ID L12039
GeneCard ID SELE
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available