Identification
BMDB Protein ID BMDBP02043
Secondary Accession Numbers None
Name Brevican core protein
Synonyms Not Available
Gene Name BCAN
Protein Type Enzyme
Biological Properties
General Function Involved in hyaluronic acid binding
Specific Function May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 3
Locus Not Available
SNPs BCAN
Gene Sequence
>2739 bp
ATGGCCCCACTGTTCCTGCCCCTCCTGGCAACCCTGGTTCTGGCCTGGATCCCTGTGGCC
TTGGCTGATGCTCTGGAAGGAGACAGCTCAGAGGACAGGGCCTTCCGCGTGCGCATCGCG
GGCGACGCGCCGCTGCAGGGCGTGCTGGGCGGCGCCCTCACCATCCCATGCCACGTTCAC
TACCTGCGGCCGTCGCCGAGCCGCCGGGCCGCGCAGGGCTCCCCGCGGGTTAAGTGGACC
TTCCTGTCCGGCGGCCGGGAGGCCGAGGTGCTAGTGGCGCGGGGCCTACGCGTCAAGGTG
AGCGAGGCCTACCGGTTCCGCGTGGCACTGCCTGCTTACCCGGCGTCACTCACCGACGTC
TCCCTGGTGCTGAGTGAGCTGCGGCCCAACGACTCAGGCATTTACCGCTGCGAGGTCCAG
CACGGCATCGACGACAGCAGCGACGCGGTGGAGGTCAAGGTCAAAGGGGTCGTCTTTCTC
TACCGGGAGGGCTCTGCCCGCTACGCTTTCTCCTTCGCTGGGGCCCAGGAGGCCTGTGCC
CGCATCGGAGCCCGAATCGCCACTCCGGAGCAGCTCTATGCCGCCTACCTCGGGGGCTAT
GAACAGTGTGACGCTGGCTGGCTGTCCGACCAGACCGTGAGGTATCCCATCCAGACGCCA
CGAGAGGCCTGTTATGGAGACATGGATGGCTTCCCTGGGGTCCGGAACTACGGAGTGGTC
GACCCCGATGACCTCTATGATGTTTACTGTTATGCTGAAGAACTAAATGGAGAGCTGTTC
CTGGGTGCCCCTCCAGACAAGCTGACCTTGGAGGAGGCGCGGACATACTGCCAGGAGCGG
GGTGCTAAGATTGCAACCACCGGCCAGCTGTATGCAGCCTGGGATGGTGGCCTGGACCGC
TGCAGCTCTGGCTGGCTGTCTGATGGCAGTGTGCGCTACCCCATCGTCACCCCCAGCCAG
CGCTGTGGTGGGGGCCTCCCTGGTGTCAAGACTCTCTTCCTCTTCCCCAACCAGACTGGC
TTCCCCAACAAGCACAGCCGCTTCAACGTCTACTGCTTCCGAGACTCTGCCCAGCCTTCT
GCCATCCCTGAGGCAGCCAACCCAGCCTCTCACCTGGCCTCTGATGCACTGGAAGCCATT
GTCACAGTGACTGAGACCCTGGAGGAACTGAAGCTGCCCCAGGAAGCTGTGGAAAGCGAG
TCCCGAGGAGCCATCTATTCCATCCCCATTATAGAGGATGGAGGTGGTGGGAGCTCCACT
CCAGAAGACCCAGCAGAGGCCCCTAGAACCCTCCTAGAATTCGAAACCCAATCCATTGTG
CCTCCATTGGGGTCCTCAGAAGAGGAAGGCAAGGTGTTGGAGCAAGAAGAGAAATACAGG
GGTGAAGAAGAGAAAGAAGAGGAAGAAGAAGAGGAGGAGGTGGAGGATGAGGCCCTGTGG
GCCTGGCCCAGTGAGCTCAGCAGCCTGGACCCAGAGGCCCCTCTCCCCACTGAGCCCGTT
CCAGAGGAGTCACTCACCCAGGCATCGCCTCCAGTGAGGGCTGCCCTCCAGCCTGGTGTA
TCACCACCACCCTATGATGAGCCAGAGGCTCCCAGGCCTCCAAGGGTCCTTGGACCACCC
ACCAAGACCCTGCCCACTCCTAGGGAGGGGAACCTGGCATCCCCCCCACCTTCCACTCTG
GTTGGGGCAAGAGAGATAGAGGAGGAGACTGGGGGTCCTGAGCTCTCTGGGGCCCCTCGA
GGAGAGAGTGAGGAGACAGGAAGCTCCGAGGATGCCCCTTCCCTGCTTCCAGCCACACGG
GCCCCTGGGGATACCAGGGATCTGGAGACCCCCTCTGAAGAGAATTCCAGAAGAACTGTC
CCAGCAGGGACTTCAGTGCGTGCCCAGCCAGTGCTGCCCACTGACAGTGCCAGCCGTGGT
GGAGTGGCCGTGGCCCCCTCATCAGGTGACTGTGTCCCCAGCCCCTGCCACAATGGCGGG
ACATGCTTGGAGGAGGAGGAGGGGGTCCGCTGCCTGTGTTTGCCTGGCTATGGGGGGGAC
CTGTGCGATGTTGGCCTCCACTTCTGCAGCCCCGGTTGGGACGCCTTCCAGGGTGCCTGC
TACAAGCACTTTTCTGCCCGAAGGAGCTGGGAGGAGGCGGAGAACAAGTGCCGGATGTAC
GGCGCGCACCTGGCCAGCATCAGCACGCCGGAGGAACAGGACTTCATCAACAATCGATAC
CGGGAGTACCAGTGGATCGGGCTCAATGACAGGACCATCGAAGGGGATTTCCTGTGGTCA
GATGGCGTCCCCCTGCTCTATGAGAACTGGAACCCTGGGCAGCCAGACAGCTACTTCCTG
TCCGGAGAGAACTGCGTGGTTATGGTGTGGCACGATCAGGGACAATGGAGTGATGTTCCC
TGCAACTACCACCTGTCCTACACCTGCAAGATGGGGCTGGTGTCCTGTGGGCCCCCACCA
GAGCTGCCCCTGGCTGAAGTGTTTGGCCGCCCACGGCTGCGCTATGAAGTCGACACAGTG
CTTCGTTACCGGTGCCGGGAGGGGCTGACCCAGCGCAACCTACCATTGATCCGCTGCCAG
GAGAATGGTCGCTGGGGGCTTCCCCAGATCTCCTGTGTGCCCCGCAGGCCTGCTCGAGCT
CTGCGCCCAGTAGAGGCCCAAGAAGGACGTCCGTGGAGGCTCGTGGGGCACTGGAAGGCA
CGGCTGAATCCCTCTCCCAATCCTGCTCCAGGTCCCTAA
Protein Properties
Number of Residues 912
Molecular Weight 99554.0
Theoretical pI 4.42
Pfam Domain Function Not Available
Signals
  • 1-22
Transmembrane Regions Not Available
Protein Sequence
>Brevican core protein
MAPLFLPLLATLVLAWIPVALADALEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVH
YLRPSPSRRAAQGSPRVKWTFLSGGREAEVLVARGLRVKVSEAYRFRVALPAYPASLTDV
SLVLSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACA
RIGARIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVV
DPDDLYDVYCYAEELNGELFLGAPPDKLTLEEARTYCQERGAKIATTGQLYAAWDGGLDR
CSSGWLSDGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPS
AIPEAANPASHLASDALEAIVTVTETLEELKLPQEAVESESRGAIYSIPIIEDGGGGSST
PEDPAEAPRTLLEFETQSIVPPLGSSEEEGKVLEQEEKYRGEEEKEEEEEEEEVEDEALW
AWPSELSSLDPEAPLPTEPVPEESLTQASPPVRAALQPGVSPPPYDEPEAPRPPRVLGPP
TKTLPTPREGNLASPPPSTLVGAREIEEETGGPELSGAPRGESEETGSSEDAPSLLPATR
APGDTRDLETPSEENSRRTVPAGTSVRAQPVLPTDSASRGGVAVAPSSGDCVPSPCHNGG
TCLEEEEGVRCLCLPGYGGDLCDVGLHFCSPGWDAFQGACYKHFSARRSWEEAENKCRMY
GAHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFL
SGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPELPLAEVFGRPRLRYEVDTV
LRYRCREGLTQRNLPLIRCQENGRWGLPQISCVPRRPARALRPVEAQEGRPWRLVGHWKA
RLNPSPNPAPGP
GenBank ID Protein CAA53481.1
UniProtKB/Swiss-Prot ID Q28062
UniProtKB/Swiss-Prot Entry Name PGCB_BOVIN
PDB IDs Not Available
GenBank Gene ID X75887
GeneCard ID BCAN
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available