| Identification |
|---|
| BMDB Protein ID
| BMDBP02052 |
| Secondary Accession Numbers
| None |
| Name
| Pulmonary surfactant-associated protein D |
| Synonyms
|
Not Available
|
| Gene Name
| SFTPD |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 28 |
| Locus
| Not Available |
| SNPs
| SFTPD |
| Gene Sequence
|
>1110 bp
ATGCTTCTCCTCCCTCTCTCCGTGCTGCTCCTGCTCACACAGCCCTGGAGATCCCTGGGA
GCAGAAATGAAGATCTATTCCCAGAAAACAATGGCCAACGCCTGTACCCTGGTCATGTGT
AGCCCCCCGGAGGATGGTTTGCCTGGTCGTGATGGACGAGATGGGAGAGAAGGCCCCCGG
GGGGAGAAGGGAGATCCAGGTTCACCAGGACCTGCAGGACGAGCAGGAATGCCTGGACCA
GCTGGCCCTATTGGGCTGAAAGGAGACAATGGCTCTGCTGGAGAACCCGGACCAAAGGGA
GACACTGGACCACCTGGGCCTCCAGGTATGCCTGGACCAGCTGGAAGAGAGGGCCCCTCA
GGGAAGCAGGGGAGCATGGGACCTCCAGGCACACCAGGCCCCAAAGGAGACACTGGGCCC
AAAGGAGGAGTGGGTGCCCCAGGCATTCAGGGCTCCCCAGGCCCTGCAGGTCTCAAAGGA
GAGAGAGGTGCCCCTGGTGAGCCCGGAGCCCCTGGACGTGCTGGGGCACCAGGGCCTGCT
GGAGCCATAGGTCCACAGGGGCCTTCAGGTGCCAGGGGCCCCCCAGGACTGAAGGGAGAC
AGAGGTACTCCTGGAGAAAGAGGAGCAAAGGGGGAGAGTGGGCTTGCAGAGGTCAATGCT
CTCAGGCAGCGGGTGGGAATCTTAGAGGGACAACTACAACGGCTCCAGAATGCCTTCTCT
CAGTATAAGAAAGCGATGCTCTTCCCTAATGGCCGGAGTGTCGGGGAGAAGATCTTTAAG
ACGGTAGGCTCTGAAAAAACGTTTCAGGATGCCCAGCAGATCTGCACACAGGCTGGAGGA
CAGTTGCCCTCCCCACGTTCTGGAGCTGAAAACGAGGCCTTGACTCAGCTGGCCACAGCC
CAGAACAAGGCTGCTTTCCTGAGCATGAGCGACACCAGGAAGGAGGGTACTTTCATCTAC
CCCACGGGGGAGCCCCTGGTCTATTCCAACTGGGCCCCCCAGGAGCCCAACAATGATGGC
GGCTCAGAGAACTGTGTGGAGATCTTTCCCAATGGCAAGTGGAATGACAAAGTCTGCGGA
GAGCAGCGCCTCGTGATCTGCGAGTTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 369 |
| Molecular Weight
| 37405.0 |
| Theoretical pI
| 8.35 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Pulmonary surfactant-associated protein D
MLLLPLSVLLLLTQPWRSLGAEMKIYSQKTMANACTLVMCSPPEDGLPGRDGRDGREGPR
GEKGDPGSPGPAGRAGMPGPAGPIGLKGDNGSAGEPGPKGDTGPPGPPGMPGPAGREGPS
GKQGSMGPPGTPGPKGDTGPKGGVGAPGIQGSPGPAGLKGERGAPGEPGAPGRAGAPGPA
GAIGPQGPSGARGPPGLKGDRGTPGERGAKGESGLAEVNALRQRVGILEGQLQRLQNAFS
QYKKAMLFPNGRSVGEKIFKTEGSEKTFQDAQQICTQAGGQLPSPRSAAENEALTQLATA
QNKAAFLSMSDTRKEGTFIYPTGEPLVYSNWAPQEPNNDGGSENCVEIFPNGKWNDKVCG
EQRLVICEF
|
| External Links |
|---|
| GenBank ID Protein
| CAA53510.1 |
| UniProtKB/Swiss-Prot ID
| P35246 |
| UniProtKB/Swiss-Prot Entry Name
| SFTPD_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X75911 |
| GeneCard ID
| SFTPD |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
