Identification
BMDB Protein ID BMDBP02066
Secondary Accession Numbers None
Name L-selectin
Synonyms Not Available
Gene Name SELL
Protein Type Enzyme
Biological Properties
General Function Involved in protein binding
Specific Function Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 16
Locus Not Available
SNPs SELL
Gene Sequence
>1113 bp
ATGCTATGTCCATGGAAATGTCAAAATGCTCAGAGGGGCTTATGGAATGTCTTTAAACTG
TGGGTCTGGATTATGCTCTGTTGTGATTTCTTTGCTCATCATGGCACCGATTGCTGGACT
TACCATTATTCCAAAAGACCCATGCCCTGGGAAAAGGCTAGAGCGTTCTGCAGGGAAAAT
TACACAGATTTAGTTGCCATACAAAACAAGGGAGAGATCGAATACCTGAATAAGACACTT
CCCTTCAGCCGTACTTACTACTGGATTGGAATCCGGAAAGTAGAAGGGGTGTGGACTTGG
GTGGGAACCAACAAATCTCTCACTGAAGAAGCAAAGAACTGGGGTGCAGGGGAGCCCAAC
AACAGGAAGAGTAAGGAGGACTGTGTGGAAATCTATATCAAGAGGAACAAAGACTCGGGG
AAATGGAATGATGATGCCTGCCACAAAGCAAAGACAGCCCTCTGCTACACAGCTTCTTGT
AAACCCTGGTCATGCAGCGGCCATGGACAATGTGTGGAAGTCATCAATAATTACACCTGC
AACTGTGATTTGGGGTACTACGGGCCTGAGTGTCAGTTCGTGACTCAATGTGTGCCTTTG
GAGGCCCCAAAGCTGGGTACCATGGCCTGCACTCACCCTTTGGGGAACTTCAGCTTCATG
TCGCAGTGTGCCTTCAACTGCTCCAAGGGAACAGACATGATTGGGGTTGAAGAAACCACT
TGTGCACCATTTGGAAATTGGTCATCTCCAGAACCAACCTGTCGAGTGATTCAATGTGAG
CCTCTAACAGAACCCGATTTGGGAACCATGGACTGTAATCACCCCCTTGTCGACTTTGGC
TTTTCCTCCACATGCACCTTCAGTTGTTCAGAAGAAGCTGAGTTAACTGGGGAGAAAAAA
ACTATCTGTGGATTGTCTGGAAATTGGTCCAGCCCTAGTCCAAGATGTCAAAAAATAAAC
AGGACTATCTCAATAAATGAAGAGAGTGATTATAACCCCCTCTTCATCCCGGTGGCAGTT
ATGGTTACTGCATTCTCTGGGTTGGCATTTATCATTTGGCTGGCAAGGAGATTAAAAAGA
AAAAGCAAAAAGGTCTCGGAGAAGCATGGTTGA
Protein Properties
Number of Residues 370
Molecular Weight 41971.0
Theoretical pI 7.65
Pfam Domain Function Not Available
Signals
  • 1-28
Transmembrane Regions
  • 334-354
Protein Sequence
>L-selectin
MLCPWKCQNAQRGLWNVFKLWVWIMLCCDFFAHHGTDCWTYHYSKRPMPWEKARAFCREN
YTDLVAIQNKGEIEYLNKTLPFSRTYYWIGIRKVEGVWTWVGTNKSLTEEAKNWGAGEPN
NRKSKEDCVEIYIKRNKDSGKWNDDACHKAKTALCYTASCKPWSCSGHGQCVEVINNYTC
NCDLGYYGPECQFVTQCVPLEAPKLGTMACTHPLGNFSFMSQCAFNCSKGTDMIGVEETT
CAPFGNWSSPEPTCRVIQCEPLTEPDLGTMDCNHPLVDFGFSSTCTFSCSEEAELTGEKK
TICGLSGNWSSPSPRCQKINRTISINEESDYNPLFIPVAVMVTAFSGLAFIIWLARRLKR
KSKKVSEKHG
GenBank ID Protein CAA44676.1
UniProtKB/Swiss-Prot ID P98131
UniProtKB/Swiss-Prot Entry Name LYAM1_BOVIN
PDB IDs Not Available
GenBank Gene ID X62882
GeneCard ID SELL
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available