| Identification |
|---|
| BMDB Protein ID
| BMDBP02083 |
| Secondary Accession Numbers
| None |
| Name
| Choline transporter-like protein 4 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC44A4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 23 |
| Locus
| Not Available |
| SNPs
| SLC44A4 |
| Gene Sequence
|
>2124 bp
ATGGGGGGAAAACAGGACCAGGACAAGGAGGCCTACGGGAAACCAGCCAAATATGACCCC
TCCTTTCGAGGCCCCATTAGGAACAGGAGCTGCACAGATATCATCTGCTGTGTGCTCTTC
TTCCTTTTCATTCTGGGTTACATCGCCGTGGGGATCTTGGCCTGGGTGTACGGAGACCCC
AAACAAGTCCTCTACCCCAGGAACTCCACGGGGGCCTATTGCGGGATCGGGGAAAACAAA
GAGAAACCATATCTCCTATATTTCAACATCTTCAGCTGCGTCCTAAACACTAATATCATC
GCGATCGCCCAGAATGGCCTGAAGTGCCCCACGCCCCAGGTGTGTGTATCTTCCTGCCCA
GAGGCCTCATGGACCGTGGAACCGAGACAGTTCTCACAGACGGTCGAACAGGTCTTCTAC
GCAGCAAATAGGAATTTCTGTCTGCCAGGGGTGCCTGGGAACATGCAAGTACTCCAAAGC
CTACAACAGGAGCTCTGCCCCAGTTTCCTCCTGCCTTCCACTCCAGCTCTGGGGCGCTGT
TTCCCATGGACCAATAGTACCGTGCCTGAGCTCCCAGGGATCTCCAACACATCCATCTCC
CAGAGCATCAGTGGTCTTCTCGACAGCCTCAATGCCCGTGACATCAGTGTCAAGATCTTT
GAAGATTTTGCCCAGTCCTGGTATTGGATTCTTATTGCACTAGGCCTGGCTTTGGTTCTG
AGCCTGCTGTTTATCTTGCTTCTACGGCTGGTGGCCGGGCCCCTGGTGTTTGTGCTGATC
ATAGGGGTGCTGGGCGTGCTGGCGTATGGCATCTACCACTGCTGGGAAGAATATCGCGTG
CTGCGGGACAAGGGTGCCTCCATCTCCCAGCTGGGCTTCACCACCAACCTCAGTGCCTAC
AGAAACGTTCAGGAGACCTGGCTAGCCGCCTTGATCATACTGGCTGTGCTCGAAGGCGTC
CTGCTGCTGATGCTCATCTTCCTGCGGCAGCGGATTTGCATCGCCATCGCCCTCCTGAAG
GAGGCCAGCAGGGCTGTAGGATACATAATGTCCACCATGTTCTACCCGCTGGTCACCTTC
GCCCTCCTGCTTGTCTGCATTGCCTACTGGGCTATAATCGCTCTATTCCTGGCCACATCG
GGGCAACCCCAGTACGTGTTCTGGGCGCCCAACAGCAGTTTGCCCGGCTGTGAGAAAGTG
CCCATGAATACATCATGCGACCCCATGGAGCAAGTGAACTCCTCTTGTCCCGGGCTGATG
TGCGTCTTCCAGGGCTACCAGTCCACAGGCCTGGCACAGCGTTCTCTCTTCAACTTGCAA
ATCTATGCAGTTCTGGGGCTATTCTGGACCATCAACTGGGTACTGGCCCTGGGCCAGTGT
GTCCTGGCTGGGGCCTTTGCTTCCTTTTACTGGGCCTTCCACAAGCCCCGGGACATCCCT
ACCTTTCCCCTGGGCTCTGCTTTCCTGCGCACACTCCGTTACCACACGGGATCACTAGCC
TTTGGAGCCCTCATTCTGACCCTGGTGCAGATAGCTCGGGTCATCCTGGAATACATTGAC
CACAAATTGAGAGGAGCCCAGAACCCATTGACTCGCTGTATCCTGTGCTGCTTCAAGTGC
TGCCTCTGGTGTTTGGAAAAGTTCATCAAGTTCCTGAACCGCAATGCATACATCATGATT
GCCATCTACGGGAAGAACTTCTGTGTCTCAGCCAAAAACGCCTTCATGCTGCTCATGCGG
AACATTGTCAGGGTGGTCGTCCTGGACAAAGTCACAGACCTGCTACTGTTCTTTGGGAAG
CTGCTGGTGGTTGGAGGTGTCGGGGTCCTGTCCTTCTTTTTCTTCACGGGTCGCATCCCT
AGTCTGGGTAAAACCTTTGAGAATCCTCAACTCAACTATTACTGGCTGCCCATCATGGTC
TCCATCCTAGGGGCCTACCTCATCGCCAGCGGCTTCTTCAGTGTTTTTGGAATGTGTGTG
GACACTCTCTTCCTCTGTTTCTTGGAAGACTTGGAGCGGAATGATGGCTCAGCAGACCGG
CCCTACTACATGTCCAAGAGCCTTCTGAAGATTCTTGGCAAGAAGAACAAGGGGACCCCG
GGAGACAAGAAGAGGAAGAAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 707 |
| Molecular Weight
| 78938.0 |
| Theoretical pI
| 8.75 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 34-54
- 228-248
- 251-271
- 308-328
- 357-377
- 453-473
- 499-519
- 558-578
- 595-615
- 636-656
|
| Protein Sequence
|
>Choline transporter-like protein 4
MGGKQDQDKEAYGKPAKYDPSFRGPIRNRSCTDIICCVLFFLFILGYIAVGILAWVYGDP
KQVLYPRNSTGAYCGIGENKEKPYLLYFNIFSCVLNTNIIAIAQNGLKCPTPQVCVSSCP
EASWTVEPRQFSQTVEQVFYAANRNFCLPGVPGNMQVLQSLQQELCPSFLLPSTPALGRC
FPWTNSTVPELPGISNTSISQSISGLLDSLNARDISVKIFEDFAQSWYWILIALGLALVL
SLLFILLLRLVAGPLVFVLIIGVLGVLAYGIYHCWEEYRVLRDKGASISQLGFTTNLSAY
RNVQETWLAALIILAVLEGVLLLMLIFLRQRICIAIALLKEASRAVGYIMSTMFYPLVTF
ALLLVCIAYWAIIALFLATSGQPQYVFWAPNSSLPGCEKVPMNTSCDPMEQVNSSCPGLM
CVFQGYQSTGLAQRSLFNLQIYAVLGLFWTINWVLALGQCVLAGAFASFYWAFHKPRDIP
TFPLGSAFLRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGAQNPLTRCILCCFKC
CLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGK
LLVVGGVGVLSFFFFTGRIPSLGKTFENPQLNYYWLPIMVSILGAYLIASGFFSVFGMCV
DTLFLCFLEDLERNDGSADRPYYMSKSLLKILGKKNKGTPGDKKRKK
|
| External Links |
|---|
| GenBank ID Protein
| AAI33404.1 |
| UniProtKB/Swiss-Prot ID
| A3KMY4 |
| UniProtKB/Swiss-Prot Entry Name
| CTL4_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC133403 |
| GeneCard ID
| SLC44A4 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
