| Identification |
|---|
| BMDB Protein ID
| BMDBP02085 |
| Secondary Accession Numbers
| None |
| Name
| Sodium-coupled neutral amino acid transporter 2 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC38A2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| SLC38A2 |
| Gene Sequence
|
>1521 bp
ATGAAGAAAGCTGAAATGGGAAGGTTCAATATTTCCCCAGATGAGGACAGCAGCAGCTAT
AGTTCCAACAGCGACTTCAACTACTCCTACCCCACCAAACAAGCTGCTCTGAAAAGCCAT
TATGCCGATGTAGATCCTGAAAACCAGAACTTTTTACTTGAATCGAATTTGGGGAAGAAG
AAGTATGAAACTGACTTTCATCCAGGTACTACTTCCTTTGGAATGTCAGTATTTAATCTG
AGCAATGCGATTGTGGGCAGTGGAATCCTTGGGCTTTCTTATGCCATGGCTAATACTGGA
ATTGCTCTTTTTATAATTCTGTTGACATTTGTGTCAATATTTTCCCTGTATTCTGTTCAT
CTCCTTCTGAAGACTGCCAATGAAGGAGGGTCTTTATTATATGAACAGCTGGGACATAAA
GCATTTGGAATGGTTGGGAAGCTCACAGCATCTGGATCCATTACAATGCAGAACATTGGA
GCTATGTCAAGCTACCTCTTCATAGTGAAATATGAGTTACCTTTGGTGATCCAGGCATTA
ATGAACATTGAAGATACAAATGGATTGTGGTATCTGAACGGTGACTATTTGGTTCTGCTG
GTATCACTGGTGCTCATTCTTCCCTTGTCACTGTTGAGGAATTTAGGATATTTGGGATAT
ACCAGTGGCCTTTCCTTGCTGTGTATGATGTTCTTTCTGATTGTGGTGATTTTCAAGAAA
TTTCAGATTTCTTGTCCTGCGGAAATTGCTTTTCTAGTTAATGAAACAGTAAACAGCAGC
TTAACACAGCCAGCAACTTTTCTACCTGATATGGGTTTTAATAGGACTGAAAGTGATTCT
TGCCAACCACGTTATTTTATCTTCAACTCACAGACTGTCTACGCTGTGCCAATTCTGACC
TTTTCATTTGTCTGTCATCCTGCTATTCTTCCTATTTATGAAGAGCTTAAAGGCCGCAGC
CGTCGAAGAATGATGAATGTGTCCAAGATTTCCTTTTTTGCTATGTTTCTCATGTACCTG
CTTGCTGCCCTCTTTGGATACCTGACATTTTACGGACACGTTGAGTCAGAATTGCTTCAT
ACCTACTCTTCTGTCATGGAAACTGATATTCTGCTTCTCATTGTCCGTTTGGCTGTGTTG
GTGGCTGTCACCCTGACAGTACCTGTTGTCATTTTCCCAATCCGGAGTTCCATAACTCAT
TTGCTGTGTGCATCGAAAGAGTTCAGTTGGTGGCGTCATAGTGTCATTACAGTGTCTATC
TTGGTGTTTACCAATTTGCTTGTCATCTTTGTACCAAATATTAGGGATATCTTTGGTTTC
ATTGGTGCATCTGCAGCTGCTATGTTGATTTTTATTCTTCCATCTGCATTCTATATCAAG
TTAGTGAAGAAAGAACCTATGAAGTCTGTACAAAAGATTGGGGCTATGTTCTTTCTGCTC
AGTGGCATAGTGGTGATGACCGGAAGCATGGCCTTGATTGTGTTGGATTGGGTCCACAAT
GCCCCAGGAGGTGGCCATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 506 |
| Molecular Weight
| 56214.0 |
| Theoretical pI
| 7.92 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 77-97
- 103-123
- 159-179
- 189-209
- 218-238
- 293-313
- 330-350
- 372-392
- 414-434
- 437-457
- 475-495
|
| Protein Sequence
|
>Sodium-coupled neutral amino acid transporter 2
MKKAEMGRFNISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKK
KYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVH
LLLKTANEGGSLLYEQLGHKAFGMVGKLTASGSITMQNIGAMSSYLFIVKYELPLVIQAL
MNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMMFFLIVVIFKK
FQISCPAEIAFLVNETVNSSLTQPATFLPDMGFNRTESDSCQPRYFIFNSQTVYAVPILT
FSFVCHPAILPIYEELKGRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLH
TYSSVMETDILLLIVRLAVLVAVTLTVPVVIFPIRSSITHLLCASKEFSWWRHSVITVSI
LVFTNLLVIFVPNIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMKSVQKIGAMFFLL
SGIVVMTGSMALIVLDWVHNAPGGGH
|
| External Links |
|---|
| GenBank ID Protein
| AAI33548.1 |
| UniProtKB/Swiss-Prot ID
| A2VE31 |
| UniProtKB/Swiss-Prot Entry Name
| S38A2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC133547 |
| GeneCard ID
| SLC38A2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
