| Identification |
|---|
| BMDB Protein ID
| BMDBP02109 |
| Secondary Accession Numbers
| None |
| Name
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| SDHA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
| Pathways
|
- Carbohydrate metabolism
- Fumarate from succinate (eukaryal route): step 1/1
- Tricarboxylic acid cycle
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| SDHA |
| Gene Sequence
|
>2037 bp
ATGTCCGCCCTCCGGAGCAGTCAGCCGGTCCCGCGCGGACCGCCGGGGGTTGCCGCTGTG
TCGCGCTTGTGGCGCGCCCGGCGCCTGGCGCTGACCTGCACGAAGTGGCCGGCAGCATGG
CAGACAGGAACCCGCAGTTTTCACTTCACCGTTGATGGCAATAAGAGGTCGTCCGCTAAA
GTTTCAGATGCGATTTCTGCGCAGTATCCAGTTGTGGACCATGAGTTTGATGCCGTGGTG
GTTGGTGCCGGGGGGGCAGGCCTGCGGGCCGCGTTCGGCCTCTCTGAAGCAGGTTTCAAC
ACGGCCTGCGTCACGAAGCTCTTCCCCACCAGATCCCACACTGTCGCGGCCCAGGGAGGG
ATCAATGCCGCCCTGGGGAACATGGAGGAGGACAACTGGCGGTGGCACTTCTACGACACC
GTGAAAGGCTCCGACTGGCTGGGGGACCAGGACGCCATCCACTACATGACGGAGCAGGCC
CCCGCCTCTGTGGTGGAGCTGGAGAATTACGGCATGCCCTTTAGCAGAACTGAAGATGGC
AAGATCTACCAGCGTGCCTTTGGCGGACAGAGCCTCAAGTTCGGGAAGGGTGGGCAGGCC
CATCGCTGCTGCTGCGTGGCCGACCGCACGGGCCACTCGCTGCTGCACACGTTGTATGGA
AGGTCTCTGCGCTATGACACCAGCTACTTTGTGGAGTACTTTGCTCTGGACCTCCTGATG
GAGAGCGGGGAGTGCCGCGGTGTGATCGCTCTGTGCATAGAAGACGGGTCCATCCACCGC
ATCAGGGCCAGGAACACTGTCATCGCCACCGGAGGCTACGGGCGCACCTACTTCAGCTGC
ACGTCCGCCCACACCAGCACCGGGGACGGCACTGCCATGGTGACCAGGGCTGGCCTGCCC
TGCCAGGACCTGGAGTTCGTGCAGTTCCACCCCACAGGCATATATGGCGCTGGCTGTCTC
ATCACAGAGGGCTGTCGTGGAGAGGGGGGCATCCTCATCAACAGCCAGGGTGAGAGGTTC
ATGGAGCGCTACGCCCCCGTCGCTAAGGACCTGGCGTCCAGGGATGTCGTGTCCCGGTCC
ATGACCCTGGAAATCCGCGAGGGAAGAGGCTGTGGGCCCGAGAAGGACCATGTGTACCTG
CAGCTGCACCACCTGCCCCCAGCACAGCTGGCTATGCGCCTGCCTGGCATCTCAGAGACG
GCCATGATCTTCGCGGGCGTGGACGTCACCAAGGAGCCCATCCCCGTGCTTCCCACCGTG
CACTACAACATGGGTGGCATCCCCACCAACTACAAGGGGCAGGTTCTGAGGCACGTGAAT
GGCCAGGACCAGGTTGTGCCTGGCCTGTACGCATGCGGGGAGGCTGCCTGCGCCTCGGTG
CATGGTGCCAACCGTCTGGGTGCAAACTCGCTCCTGGACCTGGTTGTCTTCGGCCGGGCG
TGCGCCCTGAGCATCGCAGAGTCCTGCAGACCCGGAGATAAAGTTCCCTCGATTAAACCA
AATGCTGGGGAAGAATCTGTCATGAATCTTGACAAATTGAGATTTGCCAATGGAAGCATA
AGAACATCGGAACTGCGACTCAACATGCAGAAGTCGATGCAGAGCCATGCCGCGGTGTTC
CGTGTGGGGAGTGTGCTGCAGGAAGGCTGTGAGAAGATCAGCAGCCTCTACGGAGACCTG
CGGCATCTGAAGACGTTCGACAGGGGAATGGTCTGGAACACTGACCTGGTGGAGACCCTG
GAGCTGCAGAACCTGATGCTTTGTGCTCTGCAGACCATCTACGGAGCGGAGGCCCGGAAG
GAGTCGCGCGGCGCCCACGCCAGGGAGGACTTCAAGGAGAGGGTTGACGAGTACGATTAC
TCCAAGCCCATCCAGGGGCAGCAGAAGAAGCCCTTTGAGCAGCACTGGAGGAAGCACACG
CTCTCCTACGTTGACATCAAGACTGGGAAGGTCACCCTGGAGTACAGACCTGTAATCGAC
AGAACTTTGAACGAGACTGACTGCGCCACTGTTCCCCCAGCCATCCGCTCCTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 678 |
| Molecular Weight
| 74407.0 |
| Theoretical pI
| 7.87 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>SDHA protein
MSALRSSQPVPRGPPGVAAVSRLWRARRLALTCTKWPAAWQTGTRSFHFTVDGNKRSSAK
VSDAISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGG
INAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLM
ESGECRGVIALCIEDGSIHRIRARNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLP
CQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRGCGPEKDHVYLQLHHLPPAQLAMRLPGISETAMIFAGVDVTKEPIPVLPTV
HYNMGGIPTNYKGQVLRHVNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRA
CALSIAESCRPGDKVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVF
RVGSVLQEGCEKISSLYGDLRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARK
ESRGAHAREDFKERVDEYDYSKPIQGQQKKPFEQHWRKHTLSYVDIKTGKVTLEYRPVID
RTLNETDCATVPPAIRSY
|
| External Links |
|---|
| GenBank ID Protein
| AAI05358.1 |
| UniProtKB/Swiss-Prot ID
| Q2HJI1 |
| UniProtKB/Swiss-Prot Entry Name
| Q2HJI1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC105357 |
| GeneCard ID
| SDHA |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
