Identification
BMDB Protein ID BMDBP02116
Secondary Accession Numbers None
Name Electron transfer flavoprotein subunit alpha, mitochondrial
Synonyms Not Available
Gene Name ETFA
Protein Type Enzyme
Biological Properties
General Function Energy production and conversion
Specific Function Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 21
Locus Not Available
SNPs ETFA
Gene Sequence
>1002 bp
ATGTTCCGAGCCGCGGCTCCTGGGCAGCTCCGGCGGGCGACCTCATTGCTACGATTTCAG
AGTACCCTGGTGATAGCTGAGCATGCAAATGATACCCTTGCTCCCATTACATTAAATACC
ATCACTGCAGCCAAACATCTTGGAGGTGAAGTGTCCTGTTTAGTAGCTGGAACCAAATGT
GACAAGGTGGCACAAGATCTCTGCAAAGTAGCAGGTGTGGCGAAAGTTCTGGTGGCTCAG
CATGACGCGTACAAAGGCCTCCTTCCAGAGGAACTGACACCATTGATTTTGGCAACTCAG
AAGCAGTTTAATCACACACACATCTGTGCTGGAGCATCTGCCTTTGGAAAGAACCTTTTG
CCCAGAATAGCAGCCAAACTTGATGTTGCCCCTATTTCTGACATCATTGCAATCAAATCA
CCTGACACATTTGTGAGAACCATTTATGCAGGAAATGCTATATGTACAGTGAAGTGTGAT
GAGAAAGTGAAGGTATTTTCTGTCCGAGGAACATCTTTTGAAGCTGCAGCAGCAAGTGGA
GGTAGTGCCAGTTCAGAAAAGGCATCAAGCACTTCCCCAGTAGGAATATCAGAATGGCTT
GACCAGAAATTAACAAAAAGTGATCGGCCAGAGCTCACAGGTGCCAAAGTGGTGGTGTCT
GGTGGTCGGGGTTTGAAGAGTGGAGAGAACTTTAAGTTATTGTATGATCTGGCAGATCAA
CTACATGCTGCAGTTGGTGCTTCTCGTGCTGCTGTTGATGCTGGCTTTGTTACCAATGAC
TTGCAAGTTGGACAGACAGGAAAAATAGTGGCACCAGAACTTTATATTGCTGTAGGAATA
TCTGGAGCCATCCAGCATTTAGCTGGGATGAAAGACAGCAAGACAATTGTGGCTATCAAC
AAAGACCCAGAAGCTCCAATTTTTCAAGTGGCAGATTATGGAATAGTTGCAGATCTATTT
AAGGTTGTTCCTGAAATGACTGAGCTATTGAAGAAGAAATGA
Protein Properties
Number of Residues 333
Molecular Weight 34961.0
Theoretical pI 8.78
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 34-57
Protein Sequence
>Electron transfer flavoprotein subunit alpha, mitochondrial
MFRAAAPGQLRRATSLLRFQSTLVIAEHANDTLAPITLNTITAAKHLGGEVSCLVAGTKC
DKVAQDLCKVAGVAKVLVAQHDAYKGLLPEELTPLILATQKQFNHTHICAGASAFGKNLL
PRIAAKLDVAPISDIIAIKSPDTFVRTIYAGNAICTVKCDEKVKVFSVRGTSFEAAAASG
GSASSEKASSTSPVGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQ
LHAAVGASRAAVDAGFVTNDLQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAIN
KDPEAPIFQVADYGIVADLFKVVPEMTELLKKK
GenBank ID Protein AAI05383.1
UniProtKB/Swiss-Prot ID Q2KJE4
UniProtKB/Swiss-Prot Entry Name ETFA_BOVIN
PDB IDs
GenBank Gene ID BC105382
GeneCard ID ETFA
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available