Identification
BMDB Protein ID BMDBP02153
Secondary Accession Numbers None
Name Glucagon
Synonyms Not Available
Gene Name GCG
Protein Type Enzyme
Biological Properties
General Function Involved in hormone activity
Specific Function Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 2
Locus 2q21-q22
SNPs GCG
Gene Sequence
>543 bp
ATGAAAAGCCTTTACTTTGTGGCTGGATTGTTTGTAATGCTGGTACAAGGCAGCTGGCAA
CGTTCCCTTCAGAACACAGAGGAGAAATCCAGTTCATTCCCAGCTCCCCAGACCGACCCG
CTCGGCGATCCAGATCAGATCAATGAAGATAAGCGCCACTCGCAGGGCACATTCACCAGT
GACTACAGCAAGTACCTGGACTCCAGGCGTGCCCAGGACTTCGTGCAGTGGTTGATGAAT
ACCAAGAGAAACAAGAATAACATTGCCAAACGTCATGATGAATTTGAGAGACATGCTGAA
GGGACCTTTACCAGTGATGTAAGTTCTTATTTGGAAGGCCAAGCTGCCAAGGAATTCATT
GCTTGGCTGGTGAAAGGCCGAGGAAGGCGAGATTTCCCAGAAGAAGTCAACATCGTTGAA
GAACTCCGCCGCAGACACGCCGATGGCTCTTTCTCTGATGAGATGAACACTGTTCTCGAT
AGTCTTGCCACCCGAGACTTTATAAACTGGTTGCTTCAGACGAAAATTACTGACAGGAAG
TAA
Protein Properties
Number of Residues 180
Molecular Weight 20944.0
Theoretical pI 6.53
Pfam Domain Function Not Available
Signals
  • 1-20
Transmembrane Regions
  • 53-73
Protein Sequence
>Glucagon
MKSLYFVAGLFVMLVQGSWQRSLQNTEEKSSSFPAPQTDPLGDPDQINEDKRHSQGTFTS
DYSKYLDSRRAQDFVQWLMNTKRNKNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFI
AWLVKGRGRRDFPEEVNIVEELRRRHADGSFSDEMNTVLDSLATRDFINWLLQTKITDRK
GenBank ID Protein AAA30538.1
UniProtKB/Swiss-Prot ID P01272
UniProtKB/Swiss-Prot Entry Name GLUC_BOVIN
PDB IDs
GenBank Gene ID K00107
GeneCard ID GCG
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available