| Identification |
|---|
| BMDB Protein ID
| BMDBP02176 |
| Secondary Accession Numbers
| None |
| Name
| Aquaporin-2 |
| Synonyms
|
Not Available
|
| Gene Name
| AQP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| AQP2 |
| Gene Sequence
|
>816 bp
ATGTGGGAACTCCGGTCCATAGCCTTCTCCAGGGCAGTGCTTGCAGAGTTCCTGGCCACA
CTCCTCTTTGTCTTCTTTGGCCTCGGCTCAGCCCTCAACTGGCCACAGGCCTTGCCCTCT
GTGCTGCAGATCGCCATGGCCTTCGGTCTGGCTATCGGCACCCTGGTGCAGGCTCTGGGC
CATGTCAGTGGGGCCCATATCAACCCCGCCGTGACTGTGGCCTGCCTGGTGGGCTGCCAC
GTCTCCTTTCTCCGCGCTGTCTTCTATGTGGCCGCCCAGCTGCTGGGGGCTGTGGCCGGG
GCCGCCCTGCTCCATGAGATCACACCACCAGCTATCCGAGGGGACCTGGCTGTCAATGCC
CTCAACAACAACTCGACAGCCGGCCAGGCCGTTACTGTGGAGCTTTTCCTGACACTGCAG
CTCGTGCTCTGTATCTTCGCCTCCACTGACGAGCGCCGTGGAGACAACGTGGGCACCCCT
GCCCTCTCCATCGGGTTCTCTGTGGCCCTGGGCCACCTCCTTGGGATCCACTACACTGGC
TGCTCCATGAATCCCGCCCGCTCCCTGGCTCCAGCTATCGTCACCGGCAAGTTTGACGAC
CACTGGGTCTTCTGGATCGGACCCTTGGTGGGCGCCATCGTGGCCTCGCTCCTCTACAAC
TACGTGCTGTTCCCGCCCGCCAAGAGCCTGTCGGAGCGCCTGGCGGTGCTGAAGGGGCTG
GAGCCCGACACCGACTGGGAGGAGCGCGAAGTGCGGCGGCGGCAGTCGGTGGAGCTGCAC
TCCCCGCAGAGCCTCCCGCGCGGCAGCAAGGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 271 |
| Molecular Weight
| 28890.0 |
| Theoretical pI
| 7.23 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 12-32
- 41-59
- 86-107
- 128-148
- 157-176
- 202-222
|
| Protein Sequence
|
>Aquaporin-2
MWELRSIAFSRAVLAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLAIGTLVQALG
HVSGAHINPAVTVACLVGCHVSFLRAVFYVAAQLLGAVAGAALLHEITPPAIRGDLAVNA
LNNNSTAGQAVTVELFLTLQLVLCIFASTDERRGDNVGTPALSIGFSVALGHLLGIHYTG
CSMNPARSLAPAIVTGKFDDHWVFWIGPLVGAIVASLLYNYVLFPPAKSLSERLAVLKGL
EPDTDWEEREVRRRQSVELHSPQSLPRGSKA
|
| External Links |
|---|
| GenBank ID Protein
| AAI51513.1 |
| UniProtKB/Swiss-Prot ID
| P79099 |
| UniProtKB/Swiss-Prot Entry Name
| AQP2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC151512 |
| GeneCard ID
| AQP2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
