| Identification |
|---|
| BMDB Protein ID
| BMDBP02177 |
| Secondary Accession Numbers
| None |
| Name
| Gamma-aminobutyric acid receptor-associated protein |
| Synonyms
|
Not Available
|
| Gene Name
| GABARAP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein transport |
| Specific Function
| Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| GABARAP |
| Gene Sequence
|
>354 bp
ATGAAGTTCGTGTATAAAGAGGAGCATCCGTTCGAGAAGCGTCGCTCTGAGGGCGAAAAG
ATCCGAAAGAAATACCCGGACCGGGTCCCGGTAATAGTAGAAAAGGCTCCTAAAGCTCGG
ATAGGAGACCTGGACAAAAAGAAATACCTGGTGCCTTCTGATCTTACAGTTGGTCAGTTC
TACTTCTTAATCCGGAAGCGAATTCATCTCCGAGCAGAGGATGCCTTGTTTTTCTTCGTC
AACAACGTCATTCCGCCCACCAGTGCCACGATGGGTCAGCTGTACCAGGAACACCATGAA
GAAGACTTCTTTCTATACATTGCCTACAGTGATGAAAGTGTCTACGGTCTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 117 |
| Molecular Weight
| 13918.0 |
| Theoretical pI
| 9.21 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 72-90
- 96-118
- 143-165
- 185-205
- 212-233
- 286-304
- 324-344
- 364-386
- 407-425
- 431-457
- 469-491
|
| Protein Sequence
|
>Gamma-aminobutyric acid receptor-associated protein
MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
|
| External Links |
|---|
| GenBank ID Protein
| AAI03061.1 |
| UniProtKB/Swiss-Prot ID
| Q9GJW7 |
| UniProtKB/Swiss-Prot Entry Name
| GBRAP_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC103060 |
| GeneCard ID
| GABARAP |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
