| Identification |
|---|
| BMDB Protein ID
| BMDBP02230 |
| Secondary Accession Numbers
| None |
| Name
| Lymphatic vessel endothelial hyaluronic acid receptor 1 |
| Synonyms
|
Not Available
|
| Gene Name
| LYVE1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cell adhesion |
| Specific Function
| Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| LYVE1 |
| Gene Sequence
|
>969 bp
ATGGCCAAGTTCTTCAGCCTGGGGTTGCTTCTTGCCTCCATCTGGACCACAAGGCTCCTG
GTCCAAGGCTCTCTCCGCTCAGAAGAAATTTCCATCTTGGGACCATGCAGAATCATGGGG
GTCACCCTAGTGACCAAAAAGACACAGCCGCTTCTGAATTTCACAGAAGCCCAGGAGGCC
TGTAGGCTCGTGGGACTCACTTTGGCCAGCCAAGACCAGGTTGAAGAAGCACGGAAATTT
GGCTTTGAGACTTGCAGCTATGGATGGGTTAAAAATCAGTTCGTGGTCATCCCTCGAATT
ATCTCCAACCCCAAGTGTGGGAAGAGTGGGGTAGGCGTCGTGATTTGGAGAAGTTCACTC
AGCAGTAGGCACAGGTCCTACTGCCACAACTCATCTGATATTTGGATTAACTCCTGCCTT
CCAGAAATTATCACCACCGATGATCCCTTATTCAACACTGAAACTGCAACATACACAACA
AAACTGATGGTCAGTGACAGTACACACTCAGAATTGTCTACTGATGGTCCTGACTATGTT
ACAACGACTGTGGCTCCCCCTCTGGCTTCCACGTCTACTCCACGGAAAAGAAAATTAATT
TGCATAACAGAAGCTTTTATGGACACTAGCGCCGTAGCTACAGAAAGAGAATCAGATATT
CAAAATAGACCAGCCTTCAAGAATGAAGCTGTTGGGTTTGGAGGTGTTCCCACTGCCCTG
CTGGTGCTTGCGCTCCTCTTCTTTGCTGCGGCAGCTGGCCTCGCAGTTTGCTACGTCAAA
AGGTATGTGAAGGCATTCCCTTTTACAAATAAGAACCAGCAGAAGGAAATGATAGAAACT
AAAGTAGTAAAAGAGGAGAAGGCCGATGATAGCAACCCTAATGAGGAATCAAAGAAAATG
AATAAAACGCCAGAGGAGCCCAAGAGTCCACCCAAAACCACAGTGCGATGCCTGGAAGCT
GAAGTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 322 |
| Molecular Weight
| 35561.0 |
| Theoretical pI
| 8.13 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Lymphatic vessel endothelial hyaluronic acid receptor 1
MAKFFSLGLLLASIWTTRLLVQGSLRSEEISILGPCRIMGVTLVTKKTQPLLNFTEAQEA
CRLVGLTLASQDQVEEARKFGFETCSYGWVKNQFVVIPRIISNPKCGKSGVGVVIWRSSL
SSRHRSYCHNSSDIWINSCLPEIITTDDPLFNTETATYTTKLMVSDSTHSELSTDGPDYV
TTTVAPPLASTSTPRKRKLICITEAFMDTSAVATERESDIQNRPAFKNEAVGFGGVPTAL
LVLALLFFAAAAGLAVCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKADDSNPNEESKKM
NKTPEEPKSPPKTTVRCLEAEV
|
| External Links |
|---|
| GenBank ID Protein
| AAQ85130.1 |
| UniProtKB/Swiss-Prot ID
| Q6UC88 |
| UniProtKB/Swiss-Prot Entry Name
| LYVE1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY372937 |
| GeneCard ID
| LYVE1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
