| Identification |
|---|
| BMDB Protein ID
| BMDBP02262 |
| Secondary Accession Numbers
| None |
| Name
| Sodium channel subunit beta-4 |
| Synonyms
|
Not Available
|
| Gene Name
| SCN4B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| SCN4B |
| Gene Sequence
|
>687 bp
ATGCCCGGGGCTCGGGACCAAGGCGCAGCCCGGGCGAGATGGCTGGGCATTGGGCTTTTG
GGTCTCTTCCTGCTCCCGGTGTCCCTGTCGCTGGAGGTGTCAGTGGGAAAGGCCACCACC
ATCTACGCTGTCAACGGCACGGAGATCCTGCTACCCTGCACCTTCTCCAGCTGCTTTGGC
TTCGAGAACCTACACTTCTGGTGGTCCTACAACAGCAGTGATACATACAAGATCCTCATA
GATGGGACTGTGAAGAATGAGAAATCGGACCCCAAGGTGAAATTGAAAGATGATGACCGC
ATCACTCTGGAGGGCTCCACAAAGGAGAAAATGAACAATATTTCCATTTCGCTGAAGAAC
CTGGAGTTCAGCGACACGGGCAAATACACCTGCCACGTGAAGAACCCCAAGGAGAATGAT
TTTCAGCACCAGGCCACCATCTTCCTCCAAGTTGTTGATAAATTGGAAGAAGTGGACAAC
ACTGTGACCCTCATCATCCTGGGTGTCGTGGGCGGGGTCATTGGGCTCCTCATCTTCATC
CTGCTGGTTAAGAAGTTCATTGCCTTCATCATCAAGAAGACTCAGGAGAAGAAGAAGGAG
TGCCTCGTGAGTTCCTCAGGGAACGATAATACCGAGAATGGGTTGCCCGGCTCCAAGGCG
GAGGAGAAAGCACCAACCAAAGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 228 |
| Molecular Weight
| 25144.0 |
| Theoretical pI
| 7.94 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Sodium channel subunit beta-4
MPGARDQGAARARWLGIGLLGLFLLPVSLSLEVSVGKATTIYAVNGTEILLPCTFSSCFG
FENLHFWWSYNSSDTYKILIDGTVKNEKSDPKVKLKDDDRITLEGSTKEKMNNISISLKN
LEFSDTGKYTCHVKNPKENDFQHQATIFLQVVDKLEEVDNTVTLIILGVVGGVIGLLIFI
LLVKKFIAFIIKKTQEKKKECLVSSSGNDNTENGLPGSKAEEKAPTKV
|
| External Links |
|---|
| GenBank ID Protein
| AAI23480.1 |
| UniProtKB/Swiss-Prot ID
| Q08E08 |
| UniProtKB/Swiss-Prot Entry Name
| SCN4B_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC123479 |
| GeneCard ID
| SCN4B |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
