| Identification |
|---|
| BMDB Protein ID
| BMDBP02270 |
| Secondary Accession Numbers
| None |
| Name
| Sodium-dependent phosphate transporter 2 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC20A2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Inorganic ion transport and metabolism |
| Specific Function
| Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage calcification and vascular calcification. Functions as a retroviral receptor (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 27 |
| Locus
| Not Available |
| SNPs
| SLC20A2 |
| Gene Sequence
|
>1938 bp
ATGGCGATGGACGAGTACCTGTGGATGGTCATCTTGGGTTTTATCATAGCTTTTATCTTG
GCGTTTTCTGTGGGTGCCAATGACGTTGCCAATTCGTTTGGTACCGCCGTGGGCTCGGGC
GTGGTGACCTTGAGGCAGGCCTGTATCCTGGCTTCCATCTTCGAAACCACCGGCTCGGTG
TTGCTGGGGGCCAAAGTCGGAGAGACCATCCGGAAGGGCATCATTGACGTGAACCTATAC
AACAACACCGTGGAGACGCTCATGGCCGGGGAGGTCAGTGCCATGGTCGGCTCAGCTGTC
TGGCAGCTCATTGCGTCCTTCCTGAGGTTCCCAATCTCGGGGACTCACTGTATCGTCGGG
GCCACCATAGGGTTCTCCCTCGTCGCAATTGGTACCCAAGGTGTGCAGTGGATGGAGCTG
GTCAAGATTGTTGCTTCTTGGTTTATATCTCCACTGTTGTCTGGTTTCATGTCTGGCGTG
CTGTTTGTACTGATCAGAATGTTCATCTTAAAAAAGGAGGACCCCGTTCCTAACGGCCTC
CGGGCGCTTCCCGTGTTCTACGCCGCCACCATCGCCATCAATGTCTTCTCCATCATGTAC
ACCGGAGCCCCAGTGATGGGCCTGGTCCTCCCCATGTGGGCGATCGCCCTCATCTCCTTC
GGGGTCGCGCTGCTGTTCGCCCTCTTCGTGTGGCTCTTTGTGTGTCCGTGGATGCGGAGG
AAGATAACAGGCAAATTACAAAAAGAATGTGCTTTATCAAGAGCCTCTGATGAAAGTCTC
AATAAAATTCAGGAAGTGGAGTCCCCAGTATTTAAAGAGCTGCCAGGTGCCAAGGCTCAC
GATGACAGCACTGTCCCCCTCACGGGCTCAGCTGCGGATCCCTCGGGGACCTCAGAAAGC
ATGTCGGGGGGTCACCACCCCCGGGCCCCATATGGCCGGGCGCTGTCCATGACGCACGGC
ACCACCAAGTCGCCCGTATCCAACGGGACCTTCGGCTTCGACGGCACGGCGCGGGCCGAC
GGCCACGTGTACCACACGGTGCACAAGGACTCGGGGCTCTACAAGGACCTGCTGCACCGC
ATCCGCGACGAGCGGCCGGCCGACGGGGCCCCGCGGCAGCTGCGGCGCAACAACAGCTAC
ACGTGCTACACCGCGGCCATCTGCGGGCTGCCCGGCCTGGCCACACGCCGCGGCGACACG
CCCGCGCCCGAGGACAGCGAGAAGCTGGTGGCCGATGCCGTGGCCTACTCGCGCCGCCGG
CTGCGCTACGACAGCTACTCCAGCTACTGCAACGCTGTGGCCGAGGCGGAGATCGAGGCC
GAGGAGGGCGGCGTGGAGGTCCGGCTGGCGCCCCCGCTGGCCGAGCCCGAGCCGCCGCGC
GACGACCCGGCGGACGAGGAGAAGGAGGAGAAGGACTCACCCGAGGTGCACCTGCTCTTC
CACTTCCTGCAGGTCCTCACCGCCTGCTTCGGCTCCTTCGCGCATGGCGGAAATGATGTG
AGTAATGCCATCGGGCCCCTGGTGGCTCTGTGGCTGATTTATGAACAAGGTGCGGTCCTG
CAAGAAGCCGCGACTCCCGTCTGGCTGCTGTTTTATGGAGGGGTTGGAATTTGTACGGGC
CTCTGGGTGTGGGGGAGACGAGTGATCCAGACCATGGGGAAGGACCTCACCCCCATCACG
CCGTCCAGCGGCTTCACCATCGAACTGGCCTCGGCCTTCACCGTGGTCATCGCCTCCAAC
ATCGGGCTGCCAGTCAGCACCACACACTGCAAGGTGGGCTCGGTGGTGGCGGTGGGCTGG
ATCCGCTCGCGGAAGGCCGTGGACTGGCGCCTCTTCCGCAACATCTTCGTGGCCTGGTTC
GTGACAGTGCCCGTGGCCGGGCTGTTCAGTGCTGCTATCATGGCTCTCCTCATCCACGGG
ATCCTTCCGTTCGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 645 |
| Molecular Weight
| 69610.0 |
| Theoretical pI
| 6.62 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 6-26
- 47-67
- 87-107
- 110-130
- 143-163
- 191-211
- 214-234
- 476-496
- 524-544
- 565-579
- 587-602
- 615-635
|
| Protein Sequence
|
>Sodium-dependent phosphate transporter 2
MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSV
LLGAKVGETIRKGIIDVNLYNNTVETLMAGEVSAMVGSAVWQLIASFLRFPISGTHCIVG
ATIGFSLVAIGTQGVQWMELVKIVASWFISPLLSGFMSGVLFVLIRMFILKKEDPVPNGL
RALPVFYAATIAINVFSIMYTGAPVMGLVLPMWAIALISFGVALLFALFVWLFVCPWMRR
KITGKLQKECALSRASDESLNKIQEVESPVFKELPGAKAHDDSTVPLTGSAADPSGTSES
MSGGHHPRAPYGRALSMTHGTTKSPVSNGTFGFDGTARADGHVYHTVHKDSGLYKDLLHR
IRDERPADGAPRQLRRNNSYTCYTAAICGLPGLATRRGDTPAPEDSEKLVADAVAYSRRR
LRYDSYSSYCNAVAEAEIEAEEGGVEVRLAPPLAEPEPPRDDPADEEKEEKDSPEVHLLF
HFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYEQGAVLQEAATPVWLLFYGGVGICTG
LWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGW
IRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAIMALLIHGILPFV
|
| External Links |
|---|
| GenBank ID Protein
| AAI26507.1 |
| UniProtKB/Swiss-Prot ID
| A1A4I1 |
| UniProtKB/Swiss-Prot Entry Name
| S20A2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC126506 |
| GeneCard ID
| SLC20A2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
