Identification
BMDB Protein ID BMDBP02271
Secondary Accession Numbers None
Name Electrogenic sodium bicarbonate cotransporter 1
Synonyms Not Available
Gene Name SLC4A4
Protein Type Enzyme
Biological Properties
General Function Involved in inorganic anion exchanger activity
Specific Function Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 6
Locus Not Available
SNPs SLC4A4
Gene Sequence Not Available
Protein Properties
Number of Residues 1079
Molecular Weight 121331.0
Theoretical pI 6.84
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 467-491
  • 502-520
  • 522-542
  • 551-571
  • 586-609
  • 693-710
  • 726-745
  • 780-807
  • 820-836
  • 838-855
  • 878-894
  • 902-918
Protein Sequence
>Electrogenic sodium bicarbonate cotransporter 1
MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHREKKEKERI
SENYSDKSDVENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDG
QEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLP
QLVEMIVDHQIETGLLKPDLKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTN
PDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDSPFI
AFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKA
KDRQDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTP
PDGGHGGGGHADCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLAT
VTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLF
NFSKDHNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDA
FKKMIKLADYYPINSNFKVGYNTQFSCVCMPPDPVNISVSNDTTLAPEDLPTISSSNMYH
NATFDWAFLTTKECLKYGGKLVGNNCGFVPDITLMSFILFLGTYTSSMALKKFKTSPYFP
TTARKLISDFAIILPILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVAPFGGNPWWV
YLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVVCSFMALPW
YVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFI
PMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLC
LALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKK
KKKKGSVDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC
GenBank ID Protein AAG29539.1
UniProtKB/Swiss-Prot ID Q9GL77
UniProtKB/Swiss-Prot Entry Name S4A4_BOVIN
PDB IDs Not Available
GenBank Gene ID AF308160
GeneCard ID SLC4A4
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available