| Identification |
|---|
| BMDB Protein ID
| BMDBP02286 |
| Secondary Accession Numbers
| None |
| Name
| Sodium channel subunit beta-1 |
| Synonyms
|
Not Available
|
| Gene Name
| SCN1B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in sodium channel activity |
| Specific Function
| Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| SCN1B |
| Gene Sequence
|
>657 bp
ATGGGGACGCTGCTGGCCTTTGTGGTCGGCGCCGCACTGGTGTCCTCAGCCTGGGGGGGC
TGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATCCTGTGC
ATCTCCTGCAAGCGCCGCAGTGAGACCAACGCTGAGACCTTCACTGAGTGGACTTTCCGC
CAGAAGGGCACAGAGGAGTTTGTCAAGATCCTGCGCTATGAGAACGAGGTGCTGCAACTG
GAAGAGGATGAACGCTTTGAGGGCCGCGTGGTGTGGAACGGCAGCCGGGGCACCAAAGAC
CTGCAGGACCTGTCCATCTTCATCACCAACGTCACCTACAACCACTCGGGCGACTATGAA
TGCCACGTGTACCGCCTGCTCTTCTTCGACAACTACGAGCACAACACCAGCGTTGTCAAA
AAGATCCACCTTGAGGTGGTGGACAAAGCCAACAGAGACATGGCGTCCATCGTGTCCGAG
ATCATGATGTACGTGCTCATCGTGGTGTTGACCATCTGGCTCGTGGCAGAGATGGTTTAC
TGCTACAAGAAGATTGCCGCTGCCACGGAGGCTGCCGCACAAGAGAATGCCTCGGAATAC
TTGGCCATCACCTCAGAAAGCAAAGAGAACTGTACGGGTGTCCAGGTGGCCGAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 218 |
| Molecular Weight
| 24711.0 |
| Theoretical pI
| 4.49 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Sodium channel subunit beta-1
MGTLLAFVVGAALVSSAWGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFR
QKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYE
CHVYRLLFFDNYEHNTSVVKKIHLEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVY
CYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE
|
| External Links |
|---|
| GenBank ID Protein
| AAI18259.1 |
| UniProtKB/Swiss-Prot ID
| Q17QN4 |
| UniProtKB/Swiss-Prot Entry Name
| SCN1B_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC118258 |
| GeneCard ID
| SCN1B |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
