Showing Protein Differentially expressed in FDCP 8 homolog (BMDBP02307)
Identification | |
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BMDB Protein ID | BMDBP02307 |
Secondary Accession Numbers | None |
Name | Differentially expressed in FDCP 8 homolog |
Synonyms | Not Available |
Gene Name | DEF8 |
Protein Type | Enzyme |
Biological Properties | |
General Function | Involved in diacylglycerol binding |
Specific Function | Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. |
Pathways | Not Available |
Reactions | Not Available |
GO Classification | Not Available |
Cellular Location | Not Available |
Gene Properties | |
Chromosome Location | 18 |
Locus | Not Available |
SNPs | DEF8 |
Gene Sequence |
>1344 bp ATGGAATATGACGAGAAGCTCGCCCGGTTCCGGCAGGTCCATCTCAACCCCTTCAACAAG CAGCAGCATGAGCAGGGGGCTGGCGAGGAGGCCCCGGGCATTACTTCTCAAGCACGCCTG CCTGAGCTGCCTCCCGGGGAACCAGAGTTCCGCTGCCCAGAGCGTGTGATGGATCTTGGC CTGTCTGAGGACCACTTCGCTCGCCCCGTGGGCCTGTTCCTGGCGTCTGATGTCCAGCAG CTGCGGCAGGCCATCCAGGAGTGCAAGCAGGTCATCCTGGACCTTCCAGAGCACTCAGAG AAGCAGAAGGACGCCGTGGTGAGACTCATCCATCTCCGGCTGAAGCTTCAGGAGCTGAAG GACCCCAATGAGGATGAGCCCAACATTCGAGTCCTTCTCGAGCACCGCTTCTACAAGGAG AAGAGCAAGAGTGTGAAGCAGACATGTGACAAGTGTAACACAGTCATCTGGGGCCTCATT CAGACCTGGTACACCTGCACAGGGTGTTATTACCGCTGTCACAGCAAGTGTTTGAACCTC ATCTCCAAGCCCTGTGTGCGGTCCAAAGTCAGCCACCAGGCCGAGTATGAGCTGAACATC TGCCCTGAGGCAGGCTTGGACAGCCAGGATTACCGCTGTGCGGAGTGCCGAGCACCCATC TCTCTGCGGGGCGTGCCCAGCGAGGCCCGGCAGTGCGACTACACTGGCCAGTACTACTGC AGTCACTGCCACTGGAACGATCTGGCTGTCATCCCAGCGCGTGTGGTGCACAACTGGGAC TTCGAGCCGCGCAAGGTGTCCCGTGGCAGCATGCGCTACCTGGCGTTGATGATGTCGAGG CCAGTGCTCCGGCTCCGGGAGATCAATCCTCTGCTGTTCAACTATGTGGAGGAGCTGGTA GAGATCCGGAAGCTGCGCCAGGATATCTTGCTCATGAAGCCATATTTTATCACCTGCAGG GAGGCCATGGCAGCGCGCCTGCTCCTGCAGCTCCAGGACCGGCAGCACTTTGTGGAGAAC GATGAGATGTACTCGGTGCAGGACCTGCTGGACACGCACACGGGCCGGCTGGGCTGCTCA CTGGCTGAGACCCACACGCTGTTTGCCAAGCACATCAAACTGGACTGTGAGCGGTGCCAG GCCAAGGGCTTTGTGTGCGAGCTCTGCCGGGAGGGAGATGTGCTATTCCCCTTCGACAGC CACACATCCGTGTGCGCCGACTGCTCTGCTGTCTTCCACAGGGACTGCTACTACGACAAT TCCACCACATGCCCTAGGTGTGCGCGCCTCACCCTGCGGAAGCAGTCGCTCTTCCGGGAG CCTGGTCCAGACCTGGACGCCTGA |
Protein Properties | |
Number of Residues | 447 |
Molecular Weight | 51847.0 |
Theoretical pI | 6.93 |
Pfam Domain Function | Not Available |
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Differentially expressed in FDCP 8 homolog MEYDEKLARFRQVHLNPFNKQQHEQGAGEEAPGITSQARLPELPPGEPEFRCPERVMDLG LSEDHFARPVGLFLASDVQQLRQAIQECKQVILDLPEHSEKQKDAVVRLIHLRLKLQELK DPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTVIWGLIQTWYTCTGCYYRCHSKCLNL ISKPCVRSKVSHQAEYELNICPEAGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYC SHCHWNDLAVIPARVVHNWDFEPRKVSRGSMRYLALMMSRPVLRLREINPLLFNYVEELV EIRKLRQDILLMKPYFITCREAMAARLLLQLQDRQHFVENDEMYSVQDLLDTHTGRLGCS LAETHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRDCYYDN STTCPRCARLTLRKQSLFREPGPDLDA |
External Links | |
GenBank ID Protein | AAI42175.1 |
UniProtKB/Swiss-Prot ID | A5PJM7 |
UniProtKB/Swiss-Prot Entry Name | DEFI8_BOVIN |
PDB IDs | Not Available |
GenBank Gene ID | BC142174 |
GeneCard ID | DEF8 |
GenAtlas ID | Not Available |
HGNC ID | Not Available |
References | |
General References | Not Available |